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MAOI Magic for Bipolar 2?

30K views 6 replies 5 participants last post by  harrison  
#1 ·
Hey All,

I was just prescribed Parnate to deal with my treatment resistant depression and anxiety (possibly Bipolar 2), and I was wondering:

Do any of you out there have any experience taking MAOIs for Bipolar? If possible, please describe! What else do you take?





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Some background...My BPD is on the low scale, and my 'ups' are less of a problem than my horrendous downs. I also have ADHD.
 
#2 ·
I do not have experience with an MAOI but I do have bipolar and ADD. What I can say is that getting stabilized has helped my anxiety. Hasn't cured it, but has definitely made it more manageable. This is quite a specific question and maybe you should try posting in the medication section. Anyways, welcome!
 
#5 ·
Maois are supposed to be good for really bad depression so I imagine it should help with bad bipolar related depression as well. Have you ever tried lamictal? That's supposed to be good for bp2 depression as well. I was prescribed this but I read that hairloss is a common side effect from this drug and I don't want to make a bad problem worse!
 
#6 ·
Bronto you are lucky getting prescribed Parnate. Do you feel that your mood goes back to "normal" in between hypomanias and depressions?

I am bipolar 2 and I am taking 900 mg of lithium, 150 mg of Lamictal, 150 mg of Wellview trend, and right now I am on 30 mg of Parnate. I just reached this dose recently and I think some of thebenefits are still kicking in but I feel so much better.

I feel like bipolar 2 patients do not receive the right care. First there is an unwarranted fear of antidepressants making the situation worse. Although this is arguably true for bipolar one, I haven't seen any evidence of all that is true for bipolar 2. Many studies and literature blithely describe "bipolar" without differentiating 1 and 2.

The second problem I have seem is a myth that Bipolar depression does not respond to "antidepressants." I have seen a few studies that reach this conclusion and they all do not test whether "antidepressants" work, only whether SSRIs work. And of course the SSRIs do jack ****.

The recent trend is to put everyone on antipsychotics. The new generation of antipsychotics does not cause any dramatic problems, but there is a very significant risk of metabolic issues that lead to diabetes. This is like 20% of the people to take them. I think antipsychotics are over prescribed and the risks are underestimated.

This is why I say you are so lucky. I had to do my own research in order to get prescribed Parnate - and I am lucky enough that he is willing to work with me.

Feast your eyes on this metaanalysis: https://www.ncbi.nlm.nih.gov/m/pubmed/26479223/?i=5&from=/2053632/related
73% response rate is no joke. The average of the other therapies was like 27%. The Parnate group had 1/3 the switch rate into mania of the placebo group.

Of course I can't guarantee whether party is going to work for you individually, I would just suggest you consider the benefits, and if side effects bother you then be patient because they often go away in time.

If you have anymore questions I can probably answer some of them. It is clear from your post whether you have any specific issues you want to discuss. I just had to rant a little bit about the poor treatment quality that bipolars often receive.