It's wrong that SSRIs take 3 months to give any anxiety relief. Some positive effects can be seen within 2-4 weeks and maximum effect is seen after about 8-10 weeks for SA.I experienced major anxiety relief from Xanax while only side effects from the Lustral, which is normal since I read that I have to take Lustral for about 3 months to experience any positive effect.
The dose (50mg) was too low and I don't understand why your Pdoc didn't change your medication when it did not improve your condition. He just wasted your time.I kept taking Lustral for 5 months but I didn't notice any positive effect on SA whatsoever.
Your new Pdoc increased the dose of the Sertraline which is right. He also "augmented" it with Buspar, which didn't seem to help (Buspar on it's own is pretty useless for SA). Inderal is a beta blocker and helps with the physical symptoms of anxiety, 10mg is not a very high dose.I told my new p-doc about this and he insisted that I start taking Lustral again, which I did for the last three months. He upped my dose to 100mg and then to 150mg. He said that we can go all the way up to 300mg. He also prescribe me two meds: 10mg Inderal, and 10mg Buspar daily.
Evidence shows that you don't respond to Sertraline/Lustral even if taken at higher doses for long periods of time and "augmented" with Buspar. Your antidepressant has to be changed to eg. an SNRI like Effexor XR.My p-doc insists that I should keep taking it even though I didn't notice any effect after taking it for 5 months in a row (50mg) and then for 3 months in a row (100-150mg). The thing clearly isn't working!!
Doesn't pregabalin suffer from the same dependency issues as benzos? I've read reports of horrible withdrawal symptoms emerging. If had to be addicted to something, I'd much prefer benzos.Effexor was just an example as it is in a different substance class (SNRI), the point is: Get off the Sertraline. If your Pdoc gives you no benzos you may try Lyrica (Pregabalin). In the EU it is approved for Generalized Anxiety Disorder (GAD) and some controlled studies show it works for Social Anxiety Disorder as well. Reports on the SAS board are mixed.
Interesting. How effective did you find Lyrica for social anxiety?I have taken Lyrica for months and stopped "cold turkey" without any bad effects. I doubt Lyrica has the same abuse, tolerance or dependence issues as Benzos for most people. But it's quite possible that there exist scary reports on the internet from people who experience withdrawal or "discontinuation" syndromes after longterm use, so it's probably wise to taper down Lyrica over 2-4 weeks.
I thought it had a few mechanisms of action, one being glutamic acid decarboxylase potentiation (increased GABA).Pregabalin is not a GABAergic drug by the way like Benzos or alcohol by the way.
4/10Interesting. How effective did you find Lyrica for social anxiety?
You are right, I had the outdated manufacturer data in mind which said pregabalin was in no way GABAergic, but this seems not to be true, sorry.I thought it had a few mechanisms of action, one being glutamic acid decarboxylase potentiation (increased GABA).