Social Anxiety Support Forum banner
21 - 40 of 54 Posts

·
Registered
Joined
·
1,202 Posts
Discussion Starter · #21 ·
Hey ChopSuey? How do you manage your maintenance dose? Do you mix it up to help reduce tolerance? If you do, please tell me how, I also wanna generally be around 75-90mg
I have only noticed minor tolerance issues. But i try to generally be on a low dose 0-30mg for 2-3 days every now and then. Not very often.
 

·
Registered
Joined
·
702 Posts
what if one is stabilised on another medication or cocktail? it hardly would seem that that individual would be missing out on anything by not trialing nardil.
If someone can get the same level of benefit as nardil from a cocktail of SSRI's etc then they are very very lucky. However very few people get any benefit at all from newer medications, and if they do then it isn't usually as powerful as nardil.

Nardil is simply the most powerful antidepressant ever invented for depression and anxiety. Nothing else comes close for the majority of people.

Nardil is life changing stuff, I would even go as far as to call it a miracle.
 

·
Cheesus
Joined
·
4,144 Posts
You guys think your Nardil farts are bad, man I have been eating lots of oatmeal these days and this stuff due to its high fiber content makes me fart like king bowser himself. The smell is just unbelievable. It gets me every time. And I fart all freaking day. I know I should stop eating it but I have no woman to impress right now. Though yah you'd think i'd get used to the smell but it is atrocious every single time. You walk into my computer room and the atmosphere in here is way different than the rest of the house due to the accumulation of fart.

Anyways, Nardil doesn't give you dry mouth?
 

·
Cheesus
Joined
·
4,144 Posts
If someone can get the same level of benefit as nardil from a cocktail of SSRI's etc then they are very very lucky. However very few people get any benefit at all from newer medications, and if they do then it isn't usually as powerful as nardil.

Nardil is simply the most powerful antidepressant ever invented for depression and anxiety. Nothing else comes close for the majority of people.

Nardil is life changing stuff, I would even go as far as to call it a miracle.
It's not. It's the most powerful if anxiety is your main problem and depression is secondary. In fact, Nardil seems to make anhedonia much worse for people. And I research this a lot, it is not that great for depression, even Parnate is much better in that regard.
 

·
avui, no demà
Joined
·
3,117 Posts
yeah, i mean, we all know that reaction to psychotropics is highly idiosyncratic so stating conclusively that nardil is the best of the best is a bit lofty.

i'm stabilised and happily so. i also happen to not be taking nardil.
 

·
Registered
Joined
·
1,202 Posts
Discussion Starter · #27 ·
Anyways, Nardil doesn't give you dry mouth?
The first weeks i had small issues with dry mouth, i was constantly worrying about it, that it would get worse and I'd eventually have meth mouth. But it disappeared. And now I do try to take care of my mouth in the best possible way, cause I'm probably gonna be needing them a long time.
 

·
Registered
Joined
·
1,202 Posts
Discussion Starter · #28 ·
I thought I'd compile a list of various Nardil studies. (Can never get enough of those huh?)

Nardil vs SAD

http://informahealthcare.com/doi/abs/10.1080/08039480310002110

http://www.ncbi.nlm.nih.gov/pubmed/12607230?dopt=Abstract

http://www.ncbi.nlm.nih.gov/pubmed/20194829

http://www.ncbi.nlm.nih.gov/pubmed/12950437

http://www.ncbi.nlm.nih.gov/pubmed/12888407

http://www.ncbi.nlm.nih.gov/pubmed/9862558

http://www.ncbi.nlm.nih.gov/pubmed/12607230

http://www.ncbi.nlm.nih.gov/pubmed/15538306

http://www.ncbi.nlm.nih.gov/pubmed/10604081

http://www.ncbi.nlm.nih.gov/pubmed/22665997

Nardil vs Parnate; severe antidepressant-refractory depression

http://www.biopsychiatry.com/phenelzine-compared.htm

Nardil is neuroprotective

http://www.biopsychiatry.com/phenelzine-protect.htm

http://www.acnp.org/g4/GN401000046/Default.htm

http://www.ncbi.nlm.nih.gov/pubmed/23410524

http://www.ncbi.nlm.nih.gov/pubmed/22503968

http://www.ncbi.nlm.nih.gov/pubmed/22039878

MAOI + Tobacco smoking = Wonderful synergy

http://www.biopsychiatry.com/nicotine-mao.htm

http://www.ncbi.nlm.nih.gov/pubmed/22549121

http://www.ncbi.nlm.nih.gov/pubmed/17912044
 

·
Registered
Joined
·
677 Posts
Out of curiousity, what brand of Nardil are you taking ChopSuey? I've seen differences in opinion on the efficacy of Pfizer/Greenstone vs. Gavis, with the slight majority seeming to prefer Gavis

I myself have just started on the Greenstone generic (which supposedly has the same active & inactive ingredients as the Pfizer version, and people say Gavis is closer to the original "holy grail" pre-2003 formula change Nardil), so just wanted to know if I should maybe request a generic switch to Gavis if that's the one you take, after reading your glowing review lol.
 

·
intimacy without pain
Joined
·
1,192 Posts
It's not. It's the most powerful if anxiety is your main problem and depression is secondary. In fact, Nardil seems to make anhedonia much worse for people. And I research this a lot, it is not that great for depression, even Parnate is much better in that regard.
Can Parnate cause or exacerbate anhedonia as well? I'm pretty worried about that and also afraid of getting emotionally blunted or numb like I feel on an SSRI. :|
 

·
Registered
Joined
·
64 Posts
Can Parnate cause or exacerbate anhedonia as well? I'm pretty worried about that and also afraid of getting emotionally blunted or numb like I feel on an SSRI. :|
I have not researched this so I am not going to try to challenge kehcorpz's claims outright, but I have been on Nardil and it did not cause Anhedonia at all. Quite the opposite actually. In fact, I am somewhat shocked to to hear anyone make this claim. I was on Nardil for three years, and this runs counter to my experience.

My opinion is that Nardil is the best all-in-one drug because it is both GABAergic and dopaminergic (and serotonergic, for that matter). My theory is that the dopaminergic effects outlast the GABAergic ones however.

My advice for anyone starting out on this AD would be to begin at a low dose and titrate slowly. Pdocs and GPs don't seem to appreciate how powerful this drug is. The side affects are insane, and it blows any SSRI out of the water. I was never able to comfortably go past 45mg, to be honest, so don't feel obliged to push yourself to 60mg or 75mg just bcuz.
 

·
Registered
Joined
·
1,202 Posts
Discussion Starter · #33 ·
Out of curiousity, what brand of Nardil are you taking ChopSuey? I've seen differences in opinion on the efficacy of Pfizer/Greenstone vs. Gavis, with the slight majority seeming to prefer Gavis

I myself have just started on the Greenstone generic (which supposedly has the same active & inactive ingredients as the Pfizer version, and people say Gavis is closer to the original "holy grail" pre-2003 formula change Nardil), so just wanted to know if I should maybe request a generic switch to Gavis if that's the one you take, after reading your glowing review lol.
I take Archimedes Nardil (UK). I've however heard some rumors that Gavis Nardil is supposed to be good. But I'm not sure i believe the 2003 Nardil craze; that it became much worse after the re-formulation. All versions should have more or less the same efficacy.
 

·
Registered
Joined
·
1,202 Posts
Discussion Starter · #34 ·
I was never able to comfortably go past 45mg, to be honest, so don't feel obliged to push yourself to 60mg or 75mg just bcuz.
It's very individual how one's body handles these chemicals, i can be on 150mg without getting too much side effects, others stop abruptly because they can't handle the negative effects at 45mg.
 

·
Cheesus
Joined
·
4,144 Posts
I have not researched this so I am not going to try to challenge kehcorpz's claims outright, but I have been on Nardil and it did not cause Anhedonia at all. Quite the opposite actually. In fact, I am somewhat shocked to to hear anyone make this claim. I was on Nardil for three years, and this runs counter to my experience.

My opinion is that Nardil is the best all-in-one drug because it is both GABAergic and dopaminergic (and serotonergic, for that matter). My theory is that the dopaminergic effects outlast the GABAergic ones however.

My advice for anyone starting out on this AD would be to begin at a low dose and titrate slowly. Pdocs and GPs don't seem to appreciate how powerful this drug is. The side affects are insane, and it blows any SSRI out of the water. I was never able to comfortably go past 45mg, to be honest, so don't feel obliged to push yourself to 60mg or 75mg just bcuz.
My research was based on anecdotal reports from places like psycho-babble where people were complaining of anhedonia/apathy on it. It seems though with further digging it may be a small subset of people. It may even be that if they waited it out it would have gone away. I'm actually considering going on Nardil if Clomipramine doesn't cut it in the next 2 weeks. I'm just researching it further now and want to know everything possible before I make the dive. I'm also need to prep myself for the conversation with my doctor. Part of that convo will be convincing her to let me stay on mirtazapine for sleep just in case Nardil causes insomnia.

To those who have taken it, did you get medical bracelets? Do pharmacies have them typically?

Oh and how were cognitive functions and attention/focus?
 

·
avui, no demà
Joined
·
3,117 Posts
My research was based on anecdotal reports from places like psycho-babble where people were complaining of anhedonia/apathy on it. It seems though with further digging it may be a small subset of people. It may even be that if they waited it out it would have gone away. I'm actually considering going on Nardil if Clomipramine doesn't cut it in the next 2 weeks. I'm just researching it further now and want to know everything possible before I make the dive. I'm also need to prep myself for the conversation with my doctor. Part of that convo will be convincing her to let me stay on mirtazapine for sleep just in case Nardil causes insomnia.

To those who have taken it, did you get medical bracelets? Do pharmacies have them typically?

Oh and how were cognitive functions and attention/focus?
you're beginning to catch up to me in that you'll have tried nearly every psychotropic available in the next, um, two months? perhaps three!
 

·
Registered
Joined
·
1,202 Posts
Discussion Starter · #37 ·
To those who have taken it, did you get medical bracelets? Do pharmacies have them typically?

Oh and how were cognitive functions and attention/focus?
Bracelet; nope.
Pharmacies; Usually no.
Cognitive; short-term memory might be a little worse, barely noticeable.
Attention/focus; no difference.
 

·
Cheesus
Joined
·
4,144 Posts
you're beginning to catch up to me in that you'll have tried nearly every psychotropic available in the next, um, two months? perhaps three!
Hah we shall see. I'm hoping the MAOis are my final step. I mean these are the ones that work out most for treatment resistant depression.

Bracelet; nope.
Pharmacies; Usually no.
Cognitive; short-term memory might be a little worse, barely noticeable.
Attention/focus; no difference.
Damn, one thing clomipramine has been definitely helping with is attention/focus. Might be the NRI component. If anything I could always add a tca to the maoi that focuses on norepinephrine as it seems the combo is safe. At least according to Dr. Ken Gillman.
 

·
avui, no demà
Joined
·
3,117 Posts
Hah we shall see. I'm hoping the MAOis are my final step. I mean these are the ones that work out most for treatment resistant depression.
yeah, i'm totally done with my core cocktail and am totally not making any changes. i'm just adding things here and there to offset lyrica/luvox side effects. i absolutely cannot do what you're doing, though, unfortunately. i wish i could, but i've almost exclusively only been able to augment rather than completely touch my core team of meds.

the maoi might just do it for you - is it easy to get prescribed in canada? it's not easy to get prescribed in spain?
 

·
Cheesus
Joined
·
4,144 Posts
yeah, i'm totally done with my core cocktail and am totally not making any changes. i'm just adding things here and there to offset lyrica/luvox side effects. i absolutely cannot do what you're doing, though, unfortunately. i wish i could, but i've almost exclusively only been able to augment rather than completely touch my core team of meds.

the maoi might just do it for you - is it easy to get prescribed in canada? it's not easy to get prescribed in spain?
I honestly don't know. I never threw it at my doctor. You think maybe I should stay on clomipramine until I see her? I was going to stop it today so that I can start flushing the drug out. If she doesn't prescribe it though I don't know what I'll do. My argument will be that the clomipramine is actually more dangerous because it can cause heart issues as well as be overdosed much easier.

It would annoy me because intelligent guys like us should be able to go on these drugs without doctors worrying. It's the idiots out there who think they are invincible that are the problems.
 
21 - 40 of 54 Posts
This is an older thread, you may not receive a response, and could be reviving an old thread. Please consider creating a new thread.
Top