John Smith· Registered
Discussion Starter · #1 ·
For those who SSRIs didn't work for? I know one needs to be extremely careful, I'm considering trying it and slowly increasing the dose.
http://www.australianprescriber.com/magazine/18/4/100/1/For those who SSRIs didn't work for? I know one needs to be extremely careful, I'm considering trying it and slowly increasing the dose.
Well said Lieutenant Aldo Raine! (http://www.imdb.com/character/ch0106963/)SS stinks.
I wouldn't call Moclobemide "very effective". Psychiatrists consider it weak in general.Moclobemide is very effective...
http://www.psychotropical.com/maois_full.shtmlMany clinicians are finding that the new MAOI (or 'RIMA'), moclobemide, is not an effective antidepressant; this view is substantiated by some clinical trials which constitute evidence that moclobemide is no more effective than placebo. In my opinion it is totally ineffective, I gave up using it years, no decades, ago. The minimal effect it has on neurotransmitters is detailed in my recent review (5).
You would likely just get agitated, anxious and develop sleep problems.what would happen if you just took a load of moclobemide at once? I have a few boxes of it, but I can't be bothered wasting a month to see if it works, and then have to take it every day to maintain some sort of effect. if you took about 5-10 300mg pills at once, would it have an anti anxiety/depression effect, or would you just get sick, or just do nothing?
totallyWell said Lieutenant Aldo Raine! (http://www.imdb.com/character/ch0106963/)
that article is surely true. but not only did i take a TON of Curcumin (MAO-A inhibitor), i took it with piperine which potentiates Curcumin greatly, and also has weak MAO inhibiting properties. And i took that stuff with Effexor...but then i also took 3 capsules of Bacopa Monniera Extract...after doing alot of research, it seems Bacopa might be an unselective serotonin agonist. no wonder i got SS.http://www.psychotropical.com/5_st_moc.shtml
According to this, yes moclobemide + an SSRI will most likely result in serotonin syndrome.