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Its a thread on here about sam-e. It seems to work for a lot of people, I tried it and it did help but the affects were minimal at my dose 200-400 mg a day. And its expensive.
 

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Didn't do anything for me. Fish oil (with at least a 1000 mg of omega-3) is all around better for you. Take that first.
 

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You can do this!
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4,464 Posts
Stick with methylfolate.
 

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baclofen enthusiast
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2,748 Posts
injectable Samyr 400mg is very effective it can turn a bad day around.
 
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