Interesting... I was just reading about this Now foods supplement and planning on trying to buy it soon. The one I want is their 5-HTP blend with L-tyrosine, and it also has some B vitamins as well. I am trying to ween myself off of medication, and take something more natural instead. But I'm not sure if St. Johns Wort is the way to go, or something else, like 5-HTP.I buy mine from iherb, Now Foods brand, 100mg. I've tried others but that one is the most effective. If your main problem is anxiety 100mg upong arising will help for sure. If you feel drowsy you can take it before bed time. Don't forget to take some B6, so a potent multivitamin is a must.