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DL-Phenylalanine (D, L and DL)
Phenylalanine is an essential amino acid which is sold as nutritional supplements for its reputed pain relief and antidepressant effects.
More Info: http://en.wikipedia.org/wiki/Phenylalanine
More Info: http://en.wikipedia.org/wiki/Phenylalanine
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SAS Member
Join Date: Feb 2011
Location: Canada
Gender: Female
Age: 27
Posts: 35
I am looking into buying these. I was working out the other day and experienced my first 'runners high' due to the endorphins my body released. After this happened I wanted to find something that would cause this effect w/o exercise. I'll just cross my fingers and hope for the best!
SAS Member
Join Date: Feb 2011
Age: 32
Posts: 32
Phenylalanine is the chemical that diet soda labels warn about (it is present in aspartame). It is labeled because it is extremely dangerous to people with the condition phenylketonuria (PKU). Otherwise it is generally considered safe and found in many sugar-free and diet foods.
From the Wikipedia page:
From the Wikipedia page:
Quote:
The mechanism of DL-phenylalanine's supposed antidepressant activity may be accounted for by the precursor role of L-phenylalanine in the synthesis of the neurotransmitters norepinephrine and dopamine. Elevated brain levels of norepinephrine and dopamine are thought to have an antidepressant effect. Also, as DL-phenylalanine inhibits endorphin degradation, this leads to an inhibition of GABA release in the ventral tegmental neurons (in the midbrain), which results in greater dopamine release.
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SAS Member
Join Date: Feb 2011
Age: 32
Posts: 32
I am interested in these as well. Here's some info I've found:
Precautions:
Supplementation of L-Tyrosine may increase effectiveness.
Quote:
Originally Posted by Wikipedia
The mechanism of DL-phenylalanine's supposed antidepressant activity may be accounted for by the precursor role of L-phenylalanine in the synthesis of the neurotransmitters norepinephrine and dopamine. Elevated brain levels of norepinephrine and dopamine are thought to have an antidepressant effect. Also, as DL-phenylalanine inhibits endorphin degradation, this leads to an inhibition of GABA release in the ventral tegmental neurons (in the midbrain), which results in greater dopamine release.
Quote:
Toxicity is rare in dietary intake but large amounts in supplement form may play havoc with your blood pressure and cause headaches, nausea and heartburn. Large amounts of this nutrient may also cause nerve damage. Toxicity symptoms include increased blood pressure and emotional agitation, insomnia, headaches, and tyrosine toxicity. Individuals with PKU and women who are lactating or pregnant should avoid supplementation. People with melanomas should also avoid Phenylalanine supplementation as it may stimulate the growth of this skin cancer. L-dopa competes with phenylalanine and should not be taken at the same time of day. Doses in excess of 5,000 mg a day may be toxic and can cause nerve damage.
SAS Member
Join Date: Dec 2005
Location: Where you stay
Age: 44
Posts: 1,887
I've got some Turmeric capsules with DL-Phenylalanine.
I have really bad mood reactions to aspartame, so I'm very hesitant to try this. But, I think I'll have to try it once and see if maybe it's something else in the aspartame besides the phenylalanine.
I have really bad mood reactions to aspartame, so I'm very hesitant to try this. But, I think I'll have to try it once and see if maybe it's something else in the aspartame besides the phenylalanine.
SAS Member
Join Date: Jan 2011
Location: Siberia
Gender: Male
Posts: 707
It seems that this stuff is the only widely available enkephalinase inhibitor... but how much is it potent in this respect??
SAS Member
Join Date: Dec 2005
Location: Where you stay
Age: 44
Posts: 1,887
I've no idea how potent it is in comparison to the other, unavailable enkephalinase inhibitors. I don't know anything about this stuff.
I was reading someone's post on an opioid use site that said he used 1 gram daily to potentiate the opioids he was using. Wikipedia says that doses above 5000 grams a day are neurotoxic. My little capsule contains only 100 mg.
I wanted to add a note to my comment about aspartame-- I'm going to assume that it is the excitotoxic aspartic acid (the other 50% of aspartame besides phenylalanine) in aspartame that makes me feel so messed up.
That said, down the hatch with this lil' dl-phenylalanine and turmeric capsule.
*Gulp* ahh.
I was reading someone's post on an opioid use site that said he used 1 gram daily to potentiate the opioids he was using. Wikipedia says that doses above 5000 grams a day are neurotoxic. My little capsule contains only 100 mg.
I wanted to add a note to my comment about aspartame-- I'm going to assume that it is the excitotoxic aspartic acid (the other 50% of aspartame besides phenylalanine) in aspartame that makes me feel so messed up.
That said, down the hatch with this lil' dl-phenylalanine and turmeric capsule.
*Gulp* ahh.
SAS Member
Join Date: Sep 2011
Posts: 37
I tried dl-phenylalanine a long time ago. I took a recommended dose, it made my blood pressure sink and rise like a roller coaster - I was close to going to the emergency room. Very scary.
Top 5 Poster
Join Date: Sep 2011
Location: Not saying
Gender: Male
Posts: 6,053
Why get this, when you can just buy L-Dopa and increase dopamine levels 10 times what this or Tyrisone would do
Phenylalanine = Tyrosone = L-Dopa
Why not just buy mucuna pruiens,
Phenylalanine = Tyrosone = L-Dopa
Why not just buy mucuna pruiens,
Top 5 Poster
Join Date: Sep 2011
Location: Not saying
Gender: Male
Posts: 6,053
its been an hour since i took about 1000 MG or 1 G, which is about as much as i read from most people regarding a "high" on the bodybuilding forum
So far cant say anything different of note. Just maybe a little more energy
But nothing that promotes abilities like risk taking.
I am starting to think that more dopamine does not mean it will be used. Its just there,
So far cant say anything different of note. Just maybe a little more energy
But nothing that promotes abilities like risk taking.
I am starting to think that more dopamine does not mean it will be used. Its just there,
Top 5 Poster
Join Date: Sep 2011
Location: Not saying
Gender: Male
Posts: 6,053
I do feel more aroused generaly speaking
but its no different then caffiene of ephidrine.
Like there is no calming effect or anything like that.
but its no different then caffiene of ephidrine.
Like there is no calming effect or anything like that.
Top 5 Poster
Join Date: Sep 2011
Location: Not saying
Gender: Male
Posts: 6,053
UPDATE: 3 HOURS LATER
Mood has taken a tremandous upswing, going to gym now to do cardio as well as listening to up beat music
This is something, i take what i said back
Mood has taken a tremandous upswing, going to gym now to do cardio as well as listening to up beat music
This is something, i take what i said back
Top 5 Poster
Join Date: Sep 2011
Location: Not saying
Gender: Male
Posts: 6,053
Definately gonna take again, out of this world supplement. didnt think something like this was natural
SAS Member
Join Date: Jul 2011
Location: Connecticut
Gender: Male
Age: 29
Posts: 1,847
did nothing for me (DLP 500mg)
Top 5 Poster
Join Date: Sep 2011
Location: Not saying
Gender: Male
Posts: 6,053
I took a gram with EGCG
didnt take one today, kind of scared of the change that happens
didnt take one today, kind of scared of the change that happens
Permanently Banned
Join Date: Dec 2011
Posts: 95
Good stuff especially if you workout that day. Some is converted to tyrosine and tyrosine by itself was good so its no wonder DLPA is good too
SAS Member
Join Date: Jan 2012
Posts: 2
I took L-phynalaline for about a week and my anxiety actually got worse. When I was in situations like at the movies and church, I literally had the worst laughing attacks of my entire life! It was almost a nightmare! Once I stopped the laughing attacks Also stopped. I think it's because it increases adrenaline, and this increases anxiety in my experience because it puts you in more of a fight or flight state!
SAS Member
Join Date: Feb 2012
Location: Massachusetts
Gender: Female
Posts: 5
My mom was given DL-Phenylalanine to help quit smoking but didn't find it useful for that matter. She recommended I use it for anxiety and I'm going to use it tonight during my overnight shift at the hospital. I will report back with the effects! Anyone know if it's safe to use with St. John's Wort?
SAS Member
Join Date: Nov 2005
Posts: 13,241
Meh, had absolutely no effect on me (1000-1500 mg).
SAS Member
Join Date: Nov 2012
Location: Southern California
Gender: Male
Age: 26
Posts: 901
I love these! They're better than tyrosine and thats saying alot. Makes my work outs easier to start and makes me feel better afterwards. Damn I wish I had money to get some of these!
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