The Dexedrine didn't help at all with depression? Have you been tested for thyroid problems? They can often mimic other disorders.
It's too early for me to tell whether or not Dexedrine has helped with my depression, to be honest, and the Nardil has me constantly sleeping so it's even harder. I'm switching to Parnate so maybe I'll see some more obvious changes.
I had my TSH, T3, and T4 levels tested once, but my understanding is that some disorders (eg. Hashimoto's) can swing up and down, and "normal" levels at a given point in time can be deceptive. Perhaps I should get tested again, but I have so many complaints for my doctor that I'm always worried about coming across as a hypochondriac.
What I'm symptomatically a dead ringer for is actually hyperparathyroidism, oddly enough. At least according to written descriptions... fatigue, depression, aches and pains, excessive thirst, and CONSTANT recurring kidney stones (starting as a kid!) from apparent poor absorption of calcium. While there's been no verifiable evidence that I DO have hyperparathyroidism, vitamin D deficiency supposedly plays a huge role in its development. And as a result of shutting myself in for so many years, my vitamin D was so low at my last checkup that my GP said he's never seen that outside of a nursing home
I have a physical booked in a few weeks so I'll probably revisit a lot of these concerns again though. But even if I don't have an endocrine problem, such an extreme vitamin D deficiency definitely plays some sort of role, and I've been supplementing with high doses daily for a while now, but it will be my first opportunity to see whether my body's been absorbing it properly.
Believe me though... even before I managed to get my first appointment with a pdoc, I was trying to find a physical cause to blame things on and thyroid disorders were first on the list.