QUICK! risperdal/seroquel which is stronger - Social Anxiety Forum
 
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post #1 of 8 (permalink) Old 03-27-2012, 06:32 PM Thread Starter
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QUICK! risperdal/seroquel which is stronger


1mg of risperdal OR 150 mgs of seroquel.

out of these 2, which is stronger at blocking dopamine stimulation?
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post #2 of 8 (permalink) Old 03-27-2012, 06:47 PM
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I would say seroquel, no better way to stay comatose 24/7 lol
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post #3 of 8 (permalink) Old 03-27-2012, 06:53 PM Thread Starter
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lol okay cool
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post #4 of 8 (permalink) Old 03-27-2012, 07:22 PM
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Originally Posted by michael10364 View Post
1mg of risperdal OR 150 mgs of seroquel.

out of these 2, which is stronger at blocking dopamine stimulation?
Hi, hands down, risperdal. Yes, seroquel knocks you out at 150 mg, but that's because of its antihistamine and antiserotonergic effect.

At 150 mg the amount of D2 blockade is negligible. Significant D2 blockade from seroquel begins at 300-400 mg.

In the case of risperdal, which is less sedating than quetiapine, begins to block significant amount of D2 receptors from 1-2 mg.

In the case of AP, more sedating doesn't always mean stronger and many times is the opposite, look for example at haloperidol (not so sedating but potent) vs. chlorpromazine (weak but very sedating).

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post #5 of 8 (permalink) Old 03-27-2012, 07:43 PM
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Hi, hands down, risperdal. Yes, seroquel knocks you out at 150 mg, but that's because of its antihistamine and antiserotonergic effect.

At 150 mg the amount of D2 blockade is negligible. Significant D2 blockade from seroquel begins at 300-400 mg.

In the case of risperdal, which is less sedating than quetiapine, begins to block significant amount of D2 receptors from 1-2 mg.

In the case of AP, more sedating doesn't always mean stronger and many times is the opposite, look for example at haloperidol (not so sedating but potent) vs. chlorpromazine (weak but very sedating).
i would go with this guys opinion. i was just going on the times i have taken seroquel, i dont think i have ever had such a potent med. knocks me on my *** everytime.
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post #6 of 8 (permalink) Old 03-27-2012, 09:59 PM
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Originally Posted by ricca91 View Post
Hi, hands down, risperdal. Yes, seroquel knocks you out at 150 mg, but that's because of its antihistamine and antiserotonergic effect.

At 150 mg the amount of D2 blockade is negligible. Significant D2 blockade from seroquel begins at 300-400 mg.

In the case of risperdal, which is less sedating than quetiapine, begins to block significant amount of D2 receptors from 1-2 mg.

In the case of AP, more sedating doesn't always mean stronger and many times is the opposite, look for example at haloperidol (not so sedating but potent) vs. chlorpromazine (weak but very sedating).
this
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post #7 of 8 (permalink) Old 03-27-2012, 10:57 PM
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Originally Posted by ricca91 View Post
Hi, hands down, risperdal. Yes, seroquel knocks you out at 150 mg, but that's because of its antihistamine and antiserotonergic effect.

At 150 mg the amount of D2 blockade is negligible. Significant D2 blockade from seroquel begins at 300-400 mg.

In the case of risperdal, which is less sedating than quetiapine, begins to block significant amount of D2 receptors from 1-2 mg.

In the case of AP, more sedating doesn't always mean stronger and many times is the opposite, look for example at haloperidol (not so sedating but potent) vs. chlorpromazine (weak but very sedating).
Agreed
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post #8 of 8 (permalink) Old 03-28-2012, 12:18 PM Thread Starter
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alright, i was thinking it was risperdal that was stronger, judging by the side effects that people get from it that seem to be more related to dopamine.
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