Lexapro vs Zoloft - Social Anxiety Forum
 
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post #1 of 15 (permalink) Old 08-08-2014, 12:40 AM Thread Starter
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Lexapro vs Zoloft


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post #2 of 15 (permalink) Old 08-08-2014, 02:01 AM
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Lexapro is more selective on Serotonin, While Zoloft has some Dopamine (DAT) inhibition, and sigma-1 binding.
I have tried them both, was over a decade ago... But Zoloft was better.

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post #3 of 15 (permalink) Old 08-08-2014, 02:15 AM
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Lexapro makes me feel like a zombie. Would this be less of problem when taking zoloft?
No... Try Prozac/fluoxetine instead!

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post #4 of 15 (permalink) Old 08-08-2014, 02:18 AM
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I have used them both and I prefer zoloft. Lexapro sides were apathy and weight gain, whilst zoloft (that I am on now) side is jaw clenching.
Lexapro worked thought way better for my ocd, zoloft seems to not even touch it, but for stopping my depressive thoughts it excels.
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post #5 of 15 (permalink) Old 08-08-2014, 08:20 PM
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Neither did much for me, perhaps they muted my SA slightly, but not enough to make any kind of significant impact. Neither helped my Pure O OCD. Same sides for all SSRI's with me.

I wouldn't count on any significant dopamine effects from Zoloft. You would need to have an enormous dosage for it to affect dopamine in any way (according to my rather feeble understanding ).
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post #6 of 15 (permalink) Old 08-09-2014, 02:51 PM
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I have tried both, did not like Lexapro. I felt so numb and dead. I dearly love Zoloft among SSRIs. It may or may not be very dopaminergic but it is often stimulatory and less apathy-inducing vs Lexapro. (Your mileage may vary)

Medication-related posts are for brainstorming purposes only. Talk to your doctor.

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post #7 of 15 (permalink) Old 08-10-2014, 05:57 AM
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Zoloft helped with feelings of overwhelming irrational sadness but also made me very noticeably irritable. Lexapro I guess I could describe as more numbing emotionally but left me feeling in a more positive mood overall.

It all depends on the person what med clicks better with your personality characteristics, highs and lows, and emotional hang ups.

Not that i fully trust the safety of any psychiatric med but if you are for any reason unhappy with or even just curious if a different one could lead to a better quality of life I wouldn't hold back on trying a new one. I've tried most of them and they all suck in unique ways. Unique ways that I'm sure work better or worse for different personality types.

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post #8 of 15 (permalink) Old 08-10-2014, 05:59 AM
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I felt like being in a "bubble" on Zoloft, no really highs,or lowes...
So i would prefer Prozac/fluoxetine

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post #9 of 15 (permalink) Old 08-10-2014, 11:23 PM Thread Starter
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Quote:
Originally Posted by watertouch View Post
I felt like being in a "bubble" on Zoloft, no really highs,or lowes...
So i would prefer Prozac/fluoxetine
What did you get from prozac/fluoxetine that you didn't get from taking zoloft?
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post #10 of 15 (permalink) Old 08-11-2014, 12:23 AM
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What did you get from prozac/fluoxetine that you didn't get from taking zoloft?
Well on Zoloft i didn't really feel much, zombie, being in a bubble. Vivid dreams, waking up with panicattack...

The prozac didn't. One could always try Zoloft, everyone is different.
But it is nooted that the "zoombie,bubble feeling" happens to many that try Zoloft... Ive been on Zoloft 2times so it's not like a superbad feeling...

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post #11 of 15 (permalink) Old 08-12-2014, 04:09 AM
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Well on Zoloft i didn't really feel much, zombie, being in a bubble. Vivid dreams, waking up with panicattack...
Funny , I got those SEs from prozac. Especially the waking up with panic attack.
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post #12 of 15 (permalink) Old 08-12-2014, 06:06 AM
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Funny , I got those SEs from prozac. Especially the waking up with panic attack.
hehe i got those from Zoloft, tried Zoloft 2 times or so(but it was somewhat cool, like being in a movie) and Prozac/fluoxetine 4-5 times... But everyone works differenly!!!

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post #13 of 15 (permalink) Old 08-12-2014, 06:17 AM
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What did you get from prozac/fluoxetine that you didn't get from taking zoloft?
Also i got more "energizes"' Zoloft and Prozac are the most stimulating drugs of the SSRI-class....

While being of Prozac the first time (tried it after some more times , and hopend for the same effect) I felt some energy and being more social, rember/owerheard a friend say, damn nice to see the old Alex being back!...Of course it "poop-out"

But still....

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post #14 of 15 (permalink) Old 08-12-2014, 06:51 PM
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I can't speak for lexapro, but I've been on zoloft for close to 6 months and is really helping with SA quite a bit... I'm a lot happier and much more outgoing now. I even ended up getting a girlfriend with my reborn confidence.

I know all these medication may or may not work for everyone, but it took close to 4-5 months to get the full effects from it. Everyone's different though, thought I'd share my opinion on it.
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post #15 of 15 (permalink) Old 08-12-2014, 07:18 PM
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Lexapro made me very emotionally blunted. Although I still experienced anxious thoughts it got rid of my physical anxiety in socoial situations, no more sweating, shakyness, jitteriness. Unfortunately it made me really apathetic to everything including social situations. If anything it made me look even more awkward than I was before. It may have made me less depressed but the apathy was intense and I had apathy before I started taking it. Scary. Zoloft was pretty much identical, maybe slightly more activating, but nothing groundbreaking. In my opinion ssri's can help some people with general anxiety but for social anxiety pharmaceuticals usually aren't going to help that much
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