Effexor- Best SSRI/SNRI? - Page 2 - Social Anxiety Forum
User Tag List

Reply
 
Thread Tools
post #21 of 44 (permalink) Old 10-07-2010, 10:30 PM
SAS Member
 
Join Date: Sep 2010
Gender: Male
Age: 33
Posts: 540
Quote:
Originally Posted by seattleguy35 View Post
To be honest,

Effexor was HELL for me when I was withdrawing from it... (twice) but it works BEST for me out of all medicines so far.

I used to think Zoloft was the best, but now with Effexor AND Klonopin has "stabilized" my anxiety/depression. Yes, it's still there, but it's more stabilized and I can function.....

I'm not certain if I am correct on this one... Anyone correct me if I am wrong?

Paxil is supposedly to be the MOST potent antidepressant.. and on the bottom.. Prozac is he weakest antidepressant....

In order that I know from most potent to weakest for AD's.

Paxil
Effexor/Cymbalta
Zoloft
Lexapro/Celexa
Prozac

Others might know more?

SeattleGuy35
There are studies now published showing Zoloft and Lexapro are the most equally both the most effective antidepressants. They used a few AD's too not just ssri's in the study
Canadian4Life is offline  
Sponsored Links
Advertisement
 
post #22 of 44 (permalink) Old 10-08-2010, 01:19 PM
SAS Member
 
Join Date: Mar 2010
Posts: 480
Effexor was hell to withdraw from and I have withdrawn from 4mg klonopin. It seems that it has weak effects on NE until fairly high doses.

It didnt help me at all, it made me hyper and irritable and it cost 100$ per bottle with insurance.

I have never tried Cymbalta but it looks very promising for an SNRI drug. Perhaps when its generic I will try it. Very balanced reuptake inhibition.
Himi Jendrix is offline  
post #23 of 44 (permalink) Old 10-08-2010, 01:35 PM
Permanently Banned
 
Join Date: Sep 2010
Gender: Male
Posts: 137
I've been on Effexor for a while and it's been working really well for me, I rarely get down on myself and am more positive in my outlook. Doesn't do anything for anxiety though, but obviously an antidepressant wouldn't.
DyingInTheOutside is offline  
 
post #24 of 44 (permalink) Old 10-08-2010, 08:10 PM
SAS Member
 
jim_morrison's Avatar
 
Join Date: Aug 2008
Location: Melbourne
Gender: Male
Posts: 5,337
Quote:
Originally Posted by D.B. Cooper View Post
I disagree, try taking effexor and remeron together at any reasonable doses. It doesnt matter if you're responding to the meds because your brain is getting assaulted by such a massive amount of neurotransmitters you can barely remember your own name. Sort of like living in a dream.
I'm on effexor and remeron at the moment actually, but I don't feel like that, I just feel 'normal' and yes I remember my own name .
jim_morrison is offline  
post #25 of 44 (permalink) Old 10-08-2010, 09:21 PM
SAS Member
 
Join Date: Sep 2010
Gender: Male
Age: 33
Posts: 540
Quote:
Originally Posted by DyingInTheOutside View Post
I've been on Effexor for a while and it's been working really well for me, I rarely get down on myself and am more positive in my outlook. Doesn't do anything for anxiety though, but obviously an antidepressant wouldn't.
Glad that the effexor is working well for you! It's good to find a med that suits you. I take zoloft an antidepressant and I have been able to drop a 6 year clonazepam addiction (4mg a day) so saying antidepressants don't help anxiety is untrue they have helped me anxiety wise more than any benzo.
Canadian4Life is offline  
post #26 of 44 (permalink) Old 01-09-2011, 06:27 AM
SAS Member
 
Join Date: Jan 2011
Location: Europe
Gender: Male
Age: 35
Posts: 10

Effexor plus Guanfacine anyone????


Effexor increased my anxiety (even though i waited two or three months to see if i will adjust to the drug.. still, it didnt go away) ... the higher the dose , the higher the social anxiety problem. Was ok for depression, motivation, and mainly it was the most "clear" drug in terms of my cognitive functions. Effexor's Social Anxiety may have to do with its action on norepinephrine(noradrenaline).

Paroxetine was fine for SA , but sedating/unmotivating, not the best for my depression/motivation.

Zoloft seems fine, but Effexor was better for motivation and everything seemed crystal-clear on it (cognition-wise). I mean.. with Effexor I do not feel that my studying abilities are a bit slower. While with Zoloft or especially with Paroxetine I do feel that foggy state.

Bupropion addition to Zoloft , combined, seems superb for depression but still I feel that the foggy state (when studying etc) doesnt go away despite the addition of bupropion. Also, sweaty palms etc and mild anxiety appears.. (less or similar anxiety/sweaty palms with what i experienced at LOW dose of effexor)

So...

Effexor seemed to be the most "clear" drug for my cognition.. U know, I was feeling like when I was not on any medication.. So I WANT TO BE ABLE TO USE MY 100% OF MY POTENTIAL WHEN STUDYING.. but it's sweaty palms/sympathetic system activation/SOCIAL ANXIETY that it causes is a drawback.

---ANYONE TRIED COMBINING EFFEXOR WITH GUANFACINE(TENEX/INTUIV/GENERIC) etc ?????
(to reduce effexor's S.A. / norepinephrine problems)---


ps1. Currently on 100mg Zoloft.. it seems fine, but still this SSRI "cognitive-fog" (even though it is much milder that paroxetine's cognitive-fog) is there.. Effexor didnt have that at all.. but s.a. increase(etc. etc.) was BAD.. so i quit effexor.

ps2. Gunafacine is still not marketed in Europe so I cannot obtain it... (and also I cannot find guanfacine online... it needs a U.S./Canadian doctor prescription). Clonidine makde me feel sedated and mainly depressed(a lot) when it was combined with effexor, though it stopped the sweating(!) etc etc..
noname85 is offline  
post #27 of 44 (permalink) Old 01-12-2011, 11:36 AM
MBL
Comatose.
 
MBL's Avatar
 
Join Date: Oct 2010
Location: Halifax, NS
Gender: Male
Age: 42
Posts: 363
Effexor was the best anti-depressant I was on. I'd avoid Paxil like the plauge.

-MBL

HALIFAX, Nova Scotia (Canada)
MBL is offline  
post #28 of 44 (permalink) Old 01-12-2011, 02:47 PM
SAS Member
 
Join Date: Jan 2011
Location: Europe
Gender: Male
Age: 35
Posts: 10
Quote:
Originally Posted by MBL View Post
Effexor was the best anti-depressant I was on. I'd avoid Paxil like the plauge.
Why would YOU avoid it?
I am interested to hear of your experience..

Paxil made me feel "cognitivelly slow" towards the end oh the three years that I was using it... Apathy, lack of personal efficiency on mentally very demanding tasks etc

U?

Though it was the best for SOCIAL anxiety.

Anyone ever combined GUANFACINE(tenex) and VENLAFAXINE(effexor) here???
noname85 is offline  
post #29 of 44 (permalink) Old 01-12-2011, 03:44 PM
Guided By Voices
 
metamorphosis's Avatar
 
Join Date: Dec 2008
Location: Englewood, CO
Gender: Male
Posts: 2,396
Quote:
Originally Posted by tooker View Post
So I have tried all of the SSRI's. My doctor now wants to put me on Effexor, because she has had good results with patients she says. Does anyone think that this is probably the most powerful of the SSRI/SNRI's? I am just sick of going through the SSRI merry-go-round, as none of them have done anything for me. Remeron didnt do a damn thing either. Im thinking MAOI's are the only think that are going to help my social anxiety/depression. Anyone had success with Effexor?
Keep in mind there are alot of supplements/nootropics that are very beneficial. They can be used as an adjunct to meds.!!

- The art of progress is to preserve order amid change and to preserve change amid order.
- There is a crack in everything. That's how the light gets in.- Leonard Cohen
- The world breaks everyone and afterward many are strong at the broken places.- Ernest Hemingway
metamorphosis is offline  
post #30 of 44 (permalink) Old 01-12-2011, 03:49 PM
Guided By Voices
 
metamorphosis's Avatar
 
Join Date: Dec 2008
Location: Englewood, CO
Gender: Male
Posts: 2,396
Lexapro, 5-10 mgs in conjunction with GABAergic med. along with Dex. if you wanna go that route.Throw in some nootropics,supplements and a good diet and exercise!!

- The art of progress is to preserve order amid change and to preserve change amid order.
- There is a crack in everything. That's how the light gets in.- Leonard Cohen
- The world breaks everyone and afterward many are strong at the broken places.- Ernest Hemingway
metamorphosis is offline  
post #31 of 44 (permalink) Old 01-13-2011, 02:57 AM
SAS Member
 
robtyl's Avatar
 
Join Date: Sep 2010
Location: Melbourne, Australia
Gender: Male
Posts: 402
I'm on Pristiq (desvenlafaxine), the new Effexor (I think, too lazy to open a new tab to check).


I just realised what an earlier poster said about missing your dose by as little as two hours... perhaps THAT'S why I've been getting headaches on this stuff!


It removes the "fear" of social situations for me. But it doesn't provide me the energy/enthusiasm to be engaging. I would still think something is needed to 'pep' me up to be more outgoing.

It does give me headaches and anxiety when I don't take it on time... most nights I remember, sometimes I forget (maybe once a week... tardy, I know). Also, sometimes I'll take it at 8PM, sometimes at midnight. I think this is not a good idea, since now it's only just clicked that this might be causing the headaches! Withdrawal is going to be a *****

Motivation is not too bad on Pristiq... mostly normal. Lexapro for me was bad for motivation/energy.

Sometimes I get mild anxiety on this stuff... something I've never had. It's almost like I stress over small things, things that don't even matter. And logically I know they don't matter... but the feeling of "OMGWTFSH!T" is there. This comes and goes from time to time. Maybe once every couple of days.

Sex drive is -2/10 though. I've posted elsewhere I feel like I have no penis anymore Sex drive is extremely low, with fleeting surges of desire back to normal levels - but they're extremely short-lived.

What else? Hmm... drinking. I drink quite heavily on this stuff, and I'm mostly fine. Apparently one night I got super drunk and flopped my willy out on camera (embarassing)... another night I felt normal and had a nice warm shower, brushed my teeth and read a bit before going to sleep after a whole night of clubbing and heavy drinking. I can't really say how I am with alcohol because sometimes I'm fine, sometimes I'm not! Note this is only for heavy drinking... at normal levels (i.e. not binge-ing) you'll be fine.


That being said, I can definitely say I would prefer to be medication-free. Even with the slight benefit of reduced fear in social situations, there's nothing quite like that clearness you have with a drug-free lifestyle. I'm working towards that... unless a quick trial of Wellbutrin (as soon as I can convince my doctor to trial me on it) proves super highly motivating, without the anxiety issues some people complain about! :P Drug-free clearness might be great, but it will always come second to drug-induced wiredness with unflappable motivation


x

"When I stand before God at the end of my life, I would hope that I would not have a single bit of talent left and could say, "I used everything you gave me"."
- Erma Bombeck
robtyl is offline  
post #32 of 44 (permalink) Old 03-28-2011, 05:42 PM
New mum to summer rose
 
Arisa1536's Avatar
 
Join Date: Dec 2009
Location: Surrey UK with Hubby for christmas
Gender: Female
Posts: 1,875
Quote:
Originally Posted by Dr House View Post
I've been offered Effexor XR 3 times so far and flat out rejected it every time. I can't be bothered to go through withdrawals every day I miss a pill by as little as 2 hours, screw that!
Yeah you are right, and you are fortunate enough to be on other medications which are more powerful and less addictive or difficult to come off than effexor is.
If i could do it all over again i would be inclined to say "no thanks" because i know there are potent SNRI/SSRI's out there with little to no withdrawal effects and i have a lot of success with my TCA pamelor so yeah i kind of wish i could stop

They have good effects on anxiety and work well for binge eating disorder and other eating disorders, they do act as a slight stimulant too at first so you have energy and motivation but they are not effective in treating severe depression

the biggest issue with effexor tends to be withdrawal from them, even switching meds which can be done with SSRI's as i did, is really difficult on effexor, i mean i could easily switch from fluoxetine to paxil and from paxil to effexor but i have never experienced withdrawals' like this before, and that was dropping from 300 to 150 so i am terrified of whats going to come.

My advice would be to taper slowly off these and introduce something else like an antidepressant with less withdrawal effects and maybe a short term sedation pill like klonopin or zopiclone, because doing this alone is hell

"Some men see things as they are and say why? I dream things that never were and say why not? "
RFK quoting George Bernard Shaw



Do you think we choose the times into which we are born? Or do we fit the times we are born into?-Abraham Lincoln
Arisa1536 is offline  
post #33 of 44 (permalink) Old 08-28-2011, 09:17 AM
SAS Member
 
Join Date: Aug 2011
Posts: 2

Effexor worked the best for me


Hi, I've been prescribed Lexapro, Paxil, Effexor and right now I am on Prozac. Effexor worked best for me, but I had to stop taking it over one year ago because I was laid off from my job and lost my insurance, the cost would have been $145 for one month supply of 75mg. I was diagnosed over 10 years ago with GAD and have started and stopped meds throughout this time period.

After not taking anything for a year, suffering with my symtoms I started to do some research on my exact symptoms; shaky voice, hard to breathe, dizziness and the feeling that I had a ton of bricks on my chest when I socialized with others. This is when I finally realized that I have social anxiety, but this happens to me all the time whether I am talking to my close family members, friends or total strangers. I am not afraid of talking to anyone, have no problem in crowds, and in my mind have the confidence I need to do whatever I am doing at the time of the anxiety. So I am totally confused as to why I get so anxious over the stupidest things. If I could hide the issue from others I would not even worry about it, but my voice gets so shaky that I sound like a squeeky toy and it makes me sound like a total incompetent idiot. I try hard to control it, but I just can't do it. I've been taking prozac for over 2 months and the only thing it does for me is make me sleepy. I've read that what I need is a beta blocker. Does anyone have any suggestions or advice for me???
Brenkay is offline  
post #34 of 44 (permalink) Old 08-28-2011, 10:08 AM
SAS Member
 
Join Date: Jan 2011
Location: Europe
Gender: Male
Age: 35
Posts: 10
SAD,GAD,etc titles that have been made to make our and the physician's life easier. Think of it as a continuum , rather than isolated anxiety disorders. You may have a few symptoms from gad and a few from SAD, seems that this is the case with you. Beta blocker ? Well , who knows until u try . Do play with meds, if effexor extended release 75mg worked the best for you , GO FOR IT! Why experiment since you already found the med that worked ? :s try switch to a generic extended release version to cut costs, and yes a generic version of Effexor XR/XL/ER(or whatever, there r all basically interchangable) will work better than a complately different branded drug that didn't work for you (eg Prozac). FIND a way to pay for venlafaxine extended release. Do not play with other meds since it worked , hm? Or even Import it from Canada perhaps at a cheaper price. Generics from reputable producers work the same but do not go for other crap generics' brands just because they are one cent cheaper.

Beta blocker is not gonna be effective for ever .. Is not the first line treatment for your case , they r usually used in combination , add on treatment , the cherry on the cake , not the cake itself.

Quote:
Originally Posted by Brenkay View Post
Hi, I've been prescribed Lexapro, Paxil, Effexor and right now I am on Prozac. Effexor worked best for me, but I had to stop taking it over one year ago because I was laid off from my job and lost my insurance, the cost would have been $145 for one month supply of 75mg. I was diagnosed over 10 years ago with GAD and have started and stopped meds throughout this time period.

After not taking anything for a year, suffering with my symtoms I started to do some research on my exact symptoms; shaky voice, hard to breathe, dizziness and the feeling that I had a ton of bricks on my chest when I socialized with others. This is when I finally realized that I have social anxiety, but this happens to me all the time whether I am talking to my close family members, friends or total strangers. I am not afraid of talking to anyone, have no problem in crowds, and in my mind have the confidence I need to do whatever I am doing at the time of the anxiety. So I am totally confused as to why I get so anxious over the stupidest things. If I could hide the issue from others I would not even worry about it, but my voice gets so shaky that I sound like a squeeky toy and it makes me sound like a total incompetent idiot. I try hard to control it, but I just can't do it. I've been taking prozac for over 2 months and the only thing it does for me is make me sleepy. I've read that what I need is a beta blocker. Does anyone have any suggestions or advice for me???
noname85 is offline  
post #35 of 44 (permalink) Old 08-28-2011, 04:38 PM
SAS Member
 
CD700's Avatar
 
Join Date: Apr 2010
Location: Under rock
Gender: Male
Posts: 1,731
Quote:
Originally Posted by Brenkay View Post
Hi, I've been prescribed Lexapro, Paxil, Effexor and right now I am on Prozac. Effexor worked best for me, but I had to stop taking it over one year ago because I was laid off from my job and lost my insurance, the cost would have been $145 for one month supply of 75mg. I was diagnosed over 10 years ago with GAD and have started and stopped meds throughout this time period.

After not taking anything for a year, suffering with my symtoms I started to do some research on my exact symptoms; shaky voice, hard to breathe, dizziness and the feeling that I had a ton of bricks on my chest when I socialized with others. This is when I finally realized that I have social anxiety, but this happens to me all the time whether I am talking to my close family members, friends or total strangers. I am not afraid of talking to anyone, have no problem in crowds, and in my mind have the confidence I need to do whatever I am doing at the time of the anxiety. So I am totally confused as to why I get so anxious over the stupidest things. If I could hide the issue from others I would not even worry about it, but my voice gets so shaky that I sound like a squeeky toy and it makes me sound like a total incompetent idiot. I try hard to control it, but I just can't do it. I've been taking prozac for over 2 months and the only thing it does for me is make me sleepy. I've read that what I need is a beta blocker. Does anyone have any suggestions or advice for me???
CBT
http://en.wikipedia.org/wiki/Cogniti...vioral_therapy

Crunchy niplz
CD700 is offline  
post #36 of 44 (permalink) Old 08-28-2011, 05:01 PM
SAS Member
 
DistinctlyAmbiguous's Avatar
 
Join Date: Aug 2009
Location: California
Gender: Male
Age: 37
Posts: 342
My Mood: Mellow
Effexor is a one way road. Yes, it works for some, (even helped me a bit) but as a result of increased anxiety and acute withdrawal I increased my benzo and hypnotic usage.

All these addictive prescriptions in me at once... hell I might as well be taking opiates for my anxiety/depression.


DistinctlyAmbiguous is offline  
post #37 of 44 (permalink) Old 08-28-2011, 11:21 PM
SAS Member
 
jim_morrison's Avatar
 
Join Date: Aug 2008
Location: Melbourne
Gender: Male
Posts: 5,337
Quote:
Originally Posted by Himi Jendrix View Post
I have never tried Cymbalta but it looks very promising for an SNRI drug. Perhaps when its generic I will try it. Very balanced reuptake inhibition.
Yeah Cymbalta seems interesting, except for the liver thing.
jim_morrison is offline  
post #38 of 44 (permalink) Old 08-28-2011, 11:25 PM
Querdenker
 
hoddesdon's Avatar
 
Join Date: Jul 2011
Location: Canberra, Australia
Gender: Male
Posts: 5,684
My Mood: Confused
Beta blockers prevent the appearance of the symptoms you mentioned. You still feel the same way inside, but there is no outward sign of it.

cheer up - God is with you
hoddesdon is offline  
post #39 of 44 (permalink) Old 08-29-2011, 11:55 AM
SAS Member
 
foxy's Avatar
 
Join Date: Jul 2010
Location: england
Gender: Male
Posts: 795
effexor , when i was in the nut hospital i was put on effexor an the nurse said , i havent given a patient this for a long time. So i think its out of favour now, because of the withdrawl.
foxy is offline  
post #40 of 44 (permalink) Old 03-06-2012, 04:00 PM
SAS Member
 
Join Date: Oct 2011
Posts: 505
Quote:
Originally Posted by Dr House View Post
I've been offered Effexor XR 3 times so far and flat out rejected it every time. I can't be bothered to go through withdrawals every day I miss a pill by as little as 2 hours, screw that!
Withdrawal already when you take it 2 hours later than on the day before!?!


I get up at different times all the time. It might be that I get up at 10 AM or I might sleep til 3 PM. Does this mean I'd have to get up during the night to always take it at the same time? This is insane. What kind of **** is this? Why didn't my doctor tell me about this? This is ridiculous.
norad is offline  
Reply

Thread Tools
Show Printable Version Show Printable Version
Email this Page Email this Page



Similar Threads
Thread Thread Starter Forum Replies Last Post
Mixing Effexor(SNRI) with Paxil(SSRI)? Biron21 Medication 10 08-29-2014 10:49 AM
withdrawal from ssri/snri and irritability fraidycat Medication 6 07-02-2011 01:13 PM
SNRI VS. 'SSRI + Wellbutrin' Guide 4 Dummies Medication 6 12-30-2009 07:10 PM
SSRI verses SNRI WhiteWings Medication 7 06-03-2008 06:39 PM
SSRI + NRI = SNRI? korey Medication 4 08-28-2006 05:56 PM

Posting Rules  
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are Off
Pingbacks are Off
Refbacks are Off

 
For the best viewing experience please update your browser to Google Chrome