Carbamazepine + Tianeptine seems the best combo for my Social Anxiety. - Social Anxiety Forum
 
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post #1 of 6 (permalink) Old 10-24-2019, 02:10 PM Thread Starter
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Carbamazepine + Tianeptine seems the best combo for my Social Anxiety.


Warning ! Long text , possible mistakes since my english its not my primary language,if you're not patient read the last rows.



Like title say,i discovered this combo recently on my own,since i have left some Carbamazepine pills and i recently re-begin my Tianeptine (Stablon) treatment.

Carbamazepine also known as Tegretol is an anti-convulsant used to treat seizures,now the interesting part its " Carbamazepine is a sodium channel blocker.[28] It binds preferentially to voltage-gated sodium channels in their inactive conformation, which prevents repetitive and sustained firing of an action potential. Carbamazepine has effects on serotonin systems but the relevance to its antiseizure effects is uncertain. There is evidence that it is a serotonin releasing agent and possibly even a serotonin reuptake inhibitor "


At begining i used it for sleep aid,my doctor prescribed it for me,it didn't really help with that,i usually don't need sleep aid meds because i can sleep on my own,but when i was on SSRI (Zoloft) i was a mess.


I used to have ocassionally drinks with friends last summer,and i usually have wrost hangovers the next day like sky-rocket anxiety and tremors,so this made me to try Carbamazepine as an aid or to avoid the symptoms of hangover after a heavy night drink,this after i done a bit of research,and read some studies,usually i treated my "hangxiety" with Ativan or Diazepam,but since benzodiazepines are habbit forming i try to avoid them as much as i can.
So in one day after an heavy drink, i decided to try one pill of Carbamazepine (200mg ) it did take away the symptoms but not good enough,then i quickly reminded myself that on those studies about Carbamzepine used to treat Alcohol Withdrawal Syndrome,the doctors used the dose range up to 800 mg per day for 7 days with an slowly taper each day,like in the second day they reduced the dose to 600 mg then 400 and so on.
So i found a quite good spot for me,400 mg aka two pills per day for two days or more would get my anxiety / shakiness away and i would barely feel any of "hangxiety" symptoms, i can even drink over Carbamazepine and don't have any problems the next day,yet the drunk effect is a bit weird on Carbamazepine, i usually tend to not over do it again.


Now since in some days im quite iritable and anxious,even on Tianeptine mono-therapy,i decided recently to try to add Carbamazepine along with Tianeptine,and the effects was unexpected to be honest.its seems that Carbamazepine boost the Tianeptine effects when taken together,i get a nice euphoria feeling and anxiety its at bay most of the day, i also feel so confident and more prone to get out and talk to people and feel in general calm when i talk to them,i hardly fall into a panic attack like i usually do when im on just Tianeptine or off-meds.

So 200-400mg of Carbamazepine per day along with 12.5 mg of Tianeptine taken three times per day (12.5 x 3) seems the best way to go when i really feel at the edge or i have to go in some places where my anxiety would sky-rocket , or if i drink ocasionally and "hangxiety" kicks in the next day,the Carbamazepine its the new "benzo" for me.




However i do not tend to take Carbamazepine over a longer period of time every day, because of its awful one side effect, slight numb tongue along with an metal taste,at 400 mg, no others side effects observed in my case.

TLR : Carbamazepine seems to lower brain activity via voltage sodium channels,decreasing the anxiety indirectly / reducing chances of panic attacks,and when combined with Tianeptine its seems to boost the Tianeptine terepautic effects,with result in even less anxiety levels, + a nice euphoria when you dose Tianeptine.

And i almost forget,Carbamazepine will reduce the effects of others meds like benzodiazepines, and it was found effective in treating along with Alcohol Withdrawals , Benzodiazepines withdrawals too.


If you have any questions just ask
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post #2 of 6 (permalink) Old 12-10-2019, 01:23 PM Thread Starter
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Im surprised by the doctor opinion over my ideea of combination Carbamazepine + Tianeptine,we discuss it more a bit and he came with ideea to add Buspirone to this combo,and take carbamazepine "as needed" basis since its seems to lost its effects on anxiety / bossting tia effects after two weeks of daily use.


Carbamazepine still remain a nice tool to avoid hangovers from alcohol, if you do drink heavy at one party,take a 400mg dose of CBZ upon waking up to avoid the "anxiety doom" and other symptoms related to "hangxiety". Also CBZ is quite useful to take when you go to some places were you know that your social anxiety would trigger,again at 400mg CBZ is quite effective in blocking the physicall symptoms of anxiety,like tremors,muscle spasm,blushing and mind racing due to its abillity to lower brain activity.


Right now im focusing on Tianeptine + Buspirone combo, i'd already take it for 1.5 days (almost two),my initial dosage of BSP its 5mg twice a day along with tia 12.mg three times per day,and im still sceptikal about BSP because most people say its no more than a placeboo pill,yet i do feel it somehow, please take in mind that BSP its administred along with tianeptine, they are both work on Serotonine / Dopamine at some extend,and maybe this two drugs potentiate each other like CBZ do,at least thats what me and my doctor believe.

So far BSP + Tia combo seems to be promising,at the moment i deal with BSP side effects like dizzines and sleepiness, along with one random episode of anxiety increase / slight skakiness that i have experienced today after 4 pm,hopeefully i won't experience that again.


Regarding alcohol safety when you're on Tia + BSP , i do drinked two coups of wine like two hours ago, and its seems fine, this was mostly a test for me since i do enjoy drinking alcohol occasionally when im out with friends.


Now maybe all of you guys have this questions "why this dude do this ? " Well, im trying to find an alternative to benzodiazepines,there are no doubt that the benzos are the most effective ones along with alcohol, but if i really want to follow a treatment for my SAD and take it daily over months or years, i want that treatment to be mildy effective in the long run, and to not caause to many other problems like side effects, withdrawals, that would last for months, and made me feel a total wreck (*cough* benzos withdrawals *cough* SSRI withdrawals).
From Tianeptine or Carbamazepine, i could easily quit cold turkey without problems, withdrawals are very mild to non-existend and last mostly for 3-4 days.i still don't know the case with Buspirone, but i will find out myself, from what i've heard buspirone also dosen't seems to give awfull withdrawals upon discontinuing.


So yea, i'm still testing the tia+bsp combo,and i might come back with updates, even though nobody seems interested
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post #3 of 6 (permalink) Old 12-26-2019, 05:37 AM
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Carbamazepine has been shown to help with anxiety & depression...i took it in the past..how long have you been on it? because the side effects might go away ..


No experience with Tianeptine , it's not available here..

i am not a big fan of benzos because they don't do much for social anxiety or depression and it's not a good idea to mix them with alcohol..
i'd be careful of quitting cold turkey. for me quitting Tegretol was not easy to quit.. ..


good luck! i hope it works out..
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post #4 of 6 (permalink) Old 01-12-2020, 02:50 PM
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I am on Lexapro 15 mg, and I have some Tianeptine coming in the mail, and will be starting both in a week or two. I bought some bulk Tianeptine powder, so it should be cheaper. In Europe it is a prescription med, but in North America it is basically a obscure Nootropic/Antidepressant.
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post #5 of 6 (permalink) Old 01-14-2020, 04:59 PM Thread Starter
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I would be careful mixing Tianeptine with Lexapro, as it can cause serotonin syndrome.

@ladysmurf , in the last time i've been taken Carbamazepine daily, mostly because i kinda messed up with alcohol on holidays & new year eve, as well as with Klonopin,i never expected that i kinda abused Klonopin to get away from nasty alcohol hangovers the next day, the wrost symptom of alcohol hangover it's sky rocket anxiety + tremors, so right now i'm dealing with mild benzdiazepine withdrawal , and its nasty , especially muscle stiffness.


I really hope to get better soon, and hell i will never mess again with benzos.


By the way, what do you mean by "or me quitting Tegretol was not easy to quit" , you experienced some kind of withdrawal from it ? or rebound anxiety ?
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post #6 of 6 (permalink) Old 01-16-2020, 11:23 AM
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Quote:
Originally Posted by Marius.Petran View Post
I would be careful mixing Tianeptine with Lexapro, as it can cause serotonin syndrome.

@ladysmurf , in the last time i've been taken Carbamazepine daily, mostly because i kinda messed up with alcohol on holidays & new year eve, as well as with Klonopin,i never expected that i kinda abused Klonopin to get away from nasty alcohol hangovers the next day, the wrost symptom of alcohol hangover it's sky rocket anxiety + tremors, so right now i'm dealing with mild benzdiazepine withdrawal , and its nasty , especially muscle stiffness.


I really hope to get better soon, and hell i will never mess again with benzos.


By the way, what do you mean by "or me quitting Tegretol was not easy to quit" , you experienced some kind of withdrawal from it ? or rebound anxiety ?

not an easy withdrawal for me , but it's different for everyone...
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