baclofen and anxiety - Page 12 - Social Anxiety Forum
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post #221 of 243 (permalink) Old 06-12-2012, 05:50 PM
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I took baclofen for 3 months and didn't get anything out of it except depression.
Sounds like a great drug
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post #222 of 243 (permalink) Old 06-19-2012, 09:29 PM
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I have read through this entire thread and haven't seen this covered.
How does baclofen effect your libido (if at all)? And.. are any of you female that are taking B?

I'm so confused how to treat my anxiety (sad and gad)...after many years on AD's (ha! and the cruel SE of absolutely no sex drive) currently started Buspar....but hate messing with Serotonin, even a 5ht1a agonist. I have a rx for Baclofen after explaining the situation w/doc and wanting to get off benzos due to reliance. I just want my sex drive back...is that too much to ask?.....so sad.
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post #223 of 243 (permalink) Old 06-21-2012, 06:21 AM
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Originally Posted by Hilzy View Post
I have read through this entire thread and haven't seen this covered.
How does baclofen effect your libido (if at all)? And.. are any of you female that are taking B?

I'm so confused how to treat my anxiety (sad and gad)...after many years on AD's (ha! and the cruel SE of absolutely no sex drive) currently started Buspar....but hate messing with Serotonin, even a 5ht1a agonist. I have a rx for Baclofen after explaining the situation w/doc and wanting to get off benzos due to reliance. I just want my sex drive back...is that too much to ask?.....so sad.
For me Baclofen made me horny as hell. I believe a female friend I gave it to said that it made her kinda horny as well, but I can't be sure of this.

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Originally Posted by djp7125 View Post
I took baclofen for 3 months and didn't get anything out of it except depression.
That's pretty much what I got. Well, I got a month of super socialness then a couple months of constant crying.

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Originally Posted by brown324 View Post
Time to bring this back from the dead.

Anybody else have any personal baclofen experiences they would like to share?

I have now been on baclofen daily for about 9 months, and life is better than ever.

My daily medication is as follows:

Baclofen : 90 mg daily taken in 3 30 mg doses

Propranolol: 60 mg daily taken in 3 20 mg doses

Amitriptyline: 50 mg daily one dose

Xanax: .25 mg daily one dose

Lunesta: 3 mg daily one dose

This medication regimen has 100% cured all of my GAD my SAD and my insomnia.

The only time I ever get anxiety any more is when I think about the possibility of losing the ability to obtain these meds, as they have truly made my life worth living.
I'm glad that those are you working for you. I had a similar situation in that I was buying Parnate off the internet and my biggest fear was losing the chance to get it...which I have since lost. I might give Baclofen a try again, but it is scurry.

Interesting to note that doing ANYTHING to GabaB seems to have positive effects:

"The GABA(B) receptor positive allosteric modulator CGP 7930 and the antagonist SCH 50911 show both antidepressant and anxiolytic profile, while the GABA(B) receptor agonists (baclofen and SKF 97541) produce effects that are characteristic of antidepressant drugs."
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post #224 of 243 (permalink) Old 08-02-2012, 01:06 PM
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For the guys who've used baclofen.. were there any sexual side effects? Also, anyone use this in conjunction with a stimulant? Effects?
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post #225 of 243 (permalink) Old 08-03-2012, 03:16 AM
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I am at my wits end searching for an anxiolytic medication that works as well as the well known efficiency of benzodiazepine drugs, and am about to meet my new physiatric doctor in a couple of weeks for a medication review. The medications that show me noticable imrpovement in my chronic anxiety are Benzodiazepines, and Lyrica. My tolereance to Lyrica has gone very high now and I get no real relief unless it's in high doses. I feel that I need a Gabaergic medication wether it's A or B receptors - I just know that out of all the cocktails of drugs I've been on the Gaba ergics are the only successful 1s. My therapist said she will be mentioning how motivated I have been by quitting smoking Cannabis (It is an addiction clinic / Alcoholic clinic) they have a few doctors on the team but said that I will get a medication review if I can prove to go without smoking Cannabis or taking any other drugs (I've been self medicating) and that "people often come to try and get tablets" so this is the procedure.
Because it's an addiction centre/ Alcoholic clinic, I'm hoping that they will acknowledge my quitting of my GOLD standard Anti-anxiety self medication Cannabis daily, and offer me something like Balcofen taking on board the severity of my daily social phobia and an inibility to relax around people. I understand that my self medicating has made me prone to feeling more abnormal now in public without being stoned anymore in public/daily but seen as I've proven a cold turkey stop and a determined effort to do this and pass a drug test to prove it I hope that this time they will prescribe the right thing. If anyone has received balcofen or another Anxiolytic medication that can prove effective in the long term with effeciency through alcoholic/addiction specialists or just long term trial and error periods, let me know how it worked out for you! :/ Cheers!

Current meds : Imipramine 25mg x3 Lyrica 50mg x 2 propranolol 20mg Ritalin 5mg RitalinXR 40mg Agomelatine 25mg
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post #226 of 243 (permalink) Old 01-18-2014, 07:37 AM
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hi there,

i hope people are still coming in to read this thread. i've been taking baclofen for almost 7 months now to combat my mental addiction and cravings for alcohol. I reached the dizzy heights of 240mg (24 x 10mg tablets per day) and that enabled me to hit what is called "the switch" which turned off my mental cravings/addiction to alcohol. i've read A LOT about the benefits of baclofen for anxiety and have recently started a thread over on SAUK about it here:

http://www.social-anxiety-community....34#post1832334

with regards to libido which i've seen mentioned on here, it appears that a lot of people who are at the higher dose levels like me experience and increase in libido. for people coming off of drink this can be a real bonus not only because you're horny, but because it's better for the partner to be having sex with someone who isn't drunk basically. there are many side effects to the drug, especially at these higher doses but I didn't really experience them with any force until i hit 150mg a day. for those of you at lower doses I really would keep on soldiering through them until you reach where you want to be. however.....

CORRECT DOSING LEVELS ARE EXTREMELY IMPORTANT.

Baclofen is a powerful drung and not to be messed with. The addiction phsychiatrist who prescribed it to me started me out a 15mg per day for the first 5 days. after that, you are supposed to double it to 30mg afor 5 days and then go up by 10mg only EVERY 5 DAYS!!! going up faster and in larger amounts is not the way to do it. Going up to 60 from 40 after a couple of days is not advisable at all. you have to slowly titrate up and the same for coming down. it took me 5 and bit months to get up to 240mg per day and it will take me the same amount of time to get down to whatever maintenance dose i settle at. so basically to go from zero to 100mg per day should take no less than 45 days and coming back down to zero should take the same, 90 days in total. a lot of people get put off by the side effects but you do build up tolerance to them and although I'm taking advice from people who are in a similar situation to me and self medicate over and above our prescribed amounts, they have all comfirmed to me through their experience that these are all to be expected and safe. I have run the full gamut of side effects and all are more than manageable. if there are any questions anyone has regarding these higher levels of baclofen use or queries about the side effects please do send me a pm and I should receive an email notification about it.

best wishes....
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post #227 of 243 (permalink) Old 08-21-2014, 08:24 AM
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Hi all, im aware that this thread is a few years old now but i have come across this drug many times in my reading.

How is it working for all that have posted somfar? Has anyone started this recently for SAD?

I ask because i have tried sertraline and citalopram SSRIS, and venlafaxine for my angst. None worked, i just wish there was something out there. I know we are all different but i know a guy who was on pregablin for anxiety but did to work for him so im worried it wont for me, me and him are similar in what our angst is like.

What would be a good starting dose on this be like? I have my first ever psychiatrist appointment in a week, and would like to mention baclofen but dont know if its a good idea. He might prescribe me something completely unrelated. Also im a bit skeptical of doctors and psychs when it comes to mental health.
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post #228 of 243 (permalink) Old 08-21-2014, 08:26 AM
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But it didn't work for him* i meant to write in my prev post.
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post #229 of 243 (permalink) Old 01-21-2015, 04:59 PM
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I've personally tried quite a few different meds & supplements, in the past including Ritalin - which although made me feel pretty confident as well as off my head! haha, it ended up leaving me with physical illness, nothing I have tried has worked as well as Baclofen, it's another level.

It feels to me, personally like it's not so much masking my anxiety like I've felt with other drugs but actually preventing the chemicals that heighten or create feelings of fear & anxiety in the first place - that probably doesn't make sense or at least I guess all meds do that to some degree, but I hope you can take something from this.

I've been taking it for around 4 days & I'm noticing a big improvement not just in my anxiety but I'm experiencing a very driven mood, I only take 2.5mg twice a day, I did try 5mg twice a day but it made me feel a bit high & didn't work as well for me it. It also makes seems to make you look more youthful & your skin feel softer - no joke! it increases human growth hormone so I'm guessing this is why this occurs, the only side effect that's annoying me a bit is dealing with a dryer than usual mouth - less saliva, which can't be good for my teeth. I'm not sure how to remedy this one yet.

I would strongly recommend trying this, of course I've tried online therapy & I'd recommend some kind of therapy also, which can really help, but for me it didn't rid me of my fear & anxiety, which Baclofen helps me with.

Surprised more people don't take this, but then again I don't think it's in the prescribing guidelines for any type of anxiety, just muscles spasms in MS.
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post #230 of 243 (permalink) Old 01-21-2015, 11:01 PM
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I've personally tried quite a few different meds & supplements, in the past including Ritalin - which although made me feel pretty confident as well as off my head! haha, it ended up leaving me with physical illness, nothing I have tried has worked as well as Baclofen, it's another level.

It feels to me, personally like it's not so much masking my anxiety like I've felt with other drugs but actually preventing the chemicals that heighten or create feelings of fear & anxiety in the first place - that probably doesn't make sense or at least I guess all meds do that to some degree, but I hope you can take something from this.

I've been taking it for around 4 days & I'm noticing a big improvement not just in my anxiety but I'm experiencing a very driven mood, I only take 2.5mg twice a day, I did try 5mg twice a day but it made me feel a bit high & didn't work as well for me it. It also makes seems to make you look more youthful & your skin feel softer - no joke! it increases human growth hormone so I'm guessing this is why this occurs, the only side effect that's annoying me a bit is dealing with a dryer than usual mouth - less saliva, which can't be good for my teeth. I'm not sure how to remedy this one yet.

I would strongly recommend trying this, of course I've tried online therapy & I'd recommend some kind of therapy also, which can really help, but for me it didn't rid me of my fear & anxiety, which Baclofen helps me with.

Surprised more people don't take this, but then again I don't think it's in the prescribing guidelines for any type of anxiety, just muscles spasms in MS.
Mouthwash.. Either 'Act Dry Mouth' or 'Biotene'. There may be other brands but I use these two.
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post #231 of 243 (permalink) Old 01-26-2015, 12:58 PM
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Hi all -

I'm not sure if anyone still reads this old thread, but I'm here to revive it.

My story is similar to others - SSRIs don't help, neither did 5HTP. Developed an eating disorder when I was young, always wanting to try drugs as a youngster even though I we as a good kid - I think something has been off neurochemically from the beginning.

I've done a lot of self medicating. I'll drink even though I don't like it to ease anxiety, I've taken a variety if recreational drugs. The first time I tried a benzo was after a night of heavy cocaine use and I woke up the next day feeling better than I ever had in my entire life. It was amazing. I tried wellbutrin, Zoloft, buspar - nothing. A friend gave me some ambien which worked awesoem. At least I got a little bit of relaxation in before bed. I was prescribed benzos a few times for situational anxiety but developed a tolerance fast cause I take them everyday when I have then - not cause I'm an addict, but cause I want to feel better almost everyday. I recently tried phenibut and oh my
God I felt amazing. It was like everytime a thought came I to my head that was negative or judgemental, my brain immediately dismissed it as false. I was so full of love, my entire perception had changed. Is this how people normally feel?

I tend to say I usually feel a 6/10. I'd like to be an 8 a little more often. That's it.

So this baclofen thing is real intriguing. I don't wanna self medicate anymore, I want some support and I want to do this the right way. I don't wanna get high I just want to feel better.

It really sounds like baclofen would be what I need. I have a pdoc appointment coming up - I've actually never been - but do I just ask for this by name? Bring research papers? I don't want to buy some over the internet and give it a go, and I don't want to hurt my brain. I actually love my mind I just need it to chill the eff out a lot so I can enjoy life a little.

It will be my first trip to the pdoc so I don't want him to think I'm hunting for drugs. What so you guys recommend?

Thanks,
JS
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post #232 of 243 (permalink) Old 03-02-2015, 04:18 PM
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Barry- I am upping the dose because I don't feel 60 mg is enough, from what I have read it seems the sweet spot for most people that have *complete* anxiety relief is more or less 100-150 mg per day. You guys also have to remember that I take baclofen as well to treat addiction. I have a volitile past with addiction to amphetamines and opiates, and was finding myself drinking alcohol frequently to deal with social situations. The dosage for addiction treatment can be in excess of 300 mg per day for some people, but I know I will never get this high.

I am just following the advice of my p-doc and titrating up as he see's fit, I will be up to 100 mg in a few weeks.

I promise to continue posting results. It is so frustrating that when people find a *cure* for there illness, they stop coming to places like this and posting. I am dedicated to educating others about treatment, even if baclofen *cures* my anxiety, I will still come here and post about it in hopes that I may help others. It is this same conviction that ultimately makes me want to be a doctor, and I believe I am intelligent enough to do so, but alas, my anxiety stops life from progressing as it should. Maybe some day this dream could become a reality if I can get a real grip on my anxiety.
Hope you OK????!!!!
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post #233 of 243 (permalink) Old 03-02-2015, 04:48 PM
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hi there,

i hope people are still coming in to read this thread. i've been taking baclofen for almost 7 months now to combat my mental addiction and cravings for alcohol. I reached the dizzy heights of 240mg (24 x 10mg tablets per day) and that enabled me to hit what is called "the switch" which turned off my mental cravings/addiction to alcohol. i've read A LOT about the benefits of baclofen for anxiety and have recently started a thread over on SAUK about it here:

http://www.social-anxiety-community....34#post1832334

with regards to libido which i've seen mentioned on here, it appears that a lot of people who are at the higher dose levels like me experience and increase in libido. for people coming off of drink this can be a real bonus not only because you're horny, but because it's better for the partner to be having sex with someone who isn't drunk basically. there are many side effects to the drug, especially at these higher doses but I didn't really experience them with any force until i hit 150mg a day. for those of you at lower doses I really would keep on soldiering through them until you reach where you want to be. however.....

CORRECT DOSING LEVELS ARE EXTREMELY IMPORTANT.

Baclofen is a powerful drung and not to be messed with. The addiction phsychiatrist who prescribed it to me started me out a 15mg per day for the first 5 days. after that, you are supposed to double it to 30mg afor 5 days and then go up by 10mg only EVERY 5 DAYS!!! going up faster and in larger amounts is not the way to do it. Going up to 60 from 40 after a couple of days is not advisable at all. you have to slowly titrate up and the same for coming down. it took me 5 and bit months to get up to 240mg per day and it will take me the same amount of time to get down to whatever maintenance dose i settle at. so basically to go from zero to 100mg per day should take no less than 45 days and coming back down to zero should take the same, 90 days in total. a lot of people get put off by the side effects but you do build up tolerance to them and although I'm taking advice from people who are in a similar situation to me and self medicate over and above our prescribed amounts, they have all comfirmed to me through their experience that these are all to be expected and safe. I have run the full gamut of side effects and all are more than manageable. if there are any questions anyone has regarding these higher levels of baclofen use or queries about the side effects please do send me a pm and I should receive an email notification about it.

best wishes....
Thank you for this post, amazingly helpful guidance, how are you doing by the way?
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post #234 of 243 (permalink) Old 09-06-2016, 09:43 AM
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I am currently trying this drug. It seems to be helping me. Need to put myself in social situation to really test it though. Will update on it.
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post #235 of 243 (permalink) Old 09-06-2016, 10:00 AM
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How much do you take? Whats the onset of action?
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post #236 of 243 (permalink) Old 09-07-2016, 08:33 AM
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I took 20 mg. I felt a little sedated, and I think there was some relaxation of muscle. I felt my neck is less tense. I'm trying it now since I have a tense neck rn, and I'll see if it will ease it again.

As about side effects, it caused a little nausea. But one thing good about it is it didn't interfere with running, quite unlike propranolol, which basically kills running.

Update: a couple hours after taking 20 mg of the drug, I'm not feeling significant effects. The sedation feeling yesterday is mostly gone. It may make me relaxed because I'm not having a stiff neck, but then it's hard to say it's the drug or I just relaxed myself, because I sometimes (may be most of the times) only have stiff neck part of the day.

My body does tend to develop tolerance to drugs. I described this in another thread about propranolol. I had took some diazepam back in college when I had difficulty sleeping. I only just now realized this drug actually belongs to benzo family. Where I came from (China) it's routinely used for sleeping disorder, and could be bought without prescription. I also developed tolerance to it super fast, to the point I stopped after a few times since it's not making me sleepy at all.

More update: I just had a meeting with my supervisor, it's about 6 hours after I took the 20 mg of baclofen, I didn't feel the drug had done anything in term of easing my anxiety. I was quite my usual tense and stiff self. May be it had worn off or I need higher dosage.
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post #237 of 243 (permalink) Old 03-24-2017, 09:48 AM
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I was prescribed baclofen by my addiction doctor a few days ago. I don't know if it is because of the baclofen or because of the atarax that I'm also taking but I'm experiencing some really positive things already.

I'm taking 10mg in the morning and 10mg after dinner now for 4 days, then I will take 10 in the morning and 20 with dinner. I'm meeting with my doctor next week so that we can make some kind of plan for the future and since I'm mostly taking it for my addiction, I will probably take fairly big doses in the coming weeks.

It's no miracle cure, but as soon as a negative thought pops up into my head, I can make it disappear. Before, my thoughts would just spiral out of control and I would start crying. Now, I make them go away before they hurt me. They do still pop up fairly often, but I can make them go away.

I also noticed that I was weirdly confident talking to strangers today.

I've only been on baclofen for a few days, but it looks very promising to me.
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post #238 of 243 (permalink) Old 03-31-2017, 06:49 PM
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I read this thread in its entirety and found it fascinating on a number of counts.

First, I have suffered from severe GAD w/ episodes of panic attacks for ca. 26 years. I had absolutely no idea what was happening to me, as I had never even heard of panic attacks or anxiety disorders. This ignorance created the vintage "loop effect" of becoming fearful and further sensitized by the symptoms of anxiety.

I went an entire decade without medication and experienced suffering that is hard to put into words. I have then had several docs who attempted to cheer it with Paxil, and Xanax (as well as a few other things). Nothing was effective until my family doctor started me on Effexor and Clonozapam (the second as needed). The Effexor was the very first thing that dialed down my fight or flight response and gave me hope. However, I still lived with anxiety pretty much every day, which began to influence how I interacted with people.

I write the above preamble inasmuch as I accidentally stumbled upon Baclofen. I thought you might find my observations helpful. About three years ago I began to experience severe headaches/neck pains that were readily identified as originating in the cervical joints and adjoining muscles. I was prescribed Baclofen by a neurologist to control the muscle spasms. I had tried other muscle relaxants that were okay, but shortly after taking the Baclofen I knew something completely different was taking place. As the daily dosage increased, for the first time in nearly three decades I began to experience a completely unexpected cessation of anxiety. My anxiety can be so severe at times that I experience it even while I sleep and wake up with an anxiety attack.

To the point: at a very specific daily dosage my body was no longer capable (if that is the correct term) of triggering a panic attack. In terms of the ongoing GAD, there was no longer any anxiety present--either day or night. In terms of an analogy, it was as if the Baclofen had reached into my brain and adjusted the idle of my nervous system back down to normal level. I discovered that now that my nervous system was no longer sensitized and was back to what I had known as "normal" nearly 25 year prior, my attitude and patterns of thinking followed and became healthy again. I did not obsess about avoiding people; I began to relate to people and enjoyed going places. Again, this had all been unexpected on my part.

I likewise discovered the hard way that you absolutely cannot stop Baclofen, or even titrate at the rate that a pharmacist or neurologist will recommend. When I needed to try to strength my neck muscles, I ceased taking it as per their instructions. I was met with the most severe anxiety and muscle cramping I had ever encountered. This really scared me and made me rethink taking it at all. After several failed attempts, I researched it enough to find out that the best titration schedule was to reduce by 5mg every seven days. Any faster and you would hurt--bad.

After being off it for several months, I realized that all my previous anxiety was back, arguably even stronger than when I began the Baclofen (that may have been a subjective impression due to an experience of such peace). Consequently, with my neck still needing a muscle relaxer, I resumed the Baclofen. Once again, it completely removed what has been 2.5 decades of severe GAD with occasional panic attacks.

There are some side effects, but they are minimal compared to what it accomplishes.

I have no idea why Baclofen is not used as a front-line drug to bring relief for many who suffer with various forms of anxiety disorders. Nothing I have taken even comes close to its efficacy, and I have yet to build up any tolerance to it.

Hope this note helps some folks. Do bear in mind that attempting to suddenly stop it without a proper taper will not only be hell-on-earth; it is potentially lethal.
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post #239 of 243 (permalink) Old 04-01-2017, 02:52 PM
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Sounds potentially superior to benzos. I do wonder if it would be better than valium, which I'm currently on.
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post #240 of 243 (permalink) Old 04-30-2017, 01:22 PM
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Anyone know if Baclofen can be taken everyday without developing much of a tolerance to it's anxiolytic effects?
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