Earthworm Jim (my childhood favorite), Pitfall: A Mayan Adventure, Comix Zone (how is there no remake of this awesome concept?), Ecco the Dolphin (still gotta finish this one, and The Tides of Time), Duke Nukem 3D (regrettably, because of the creepy sexual content; still a solid FPS despite that, but if I were to play a Buld Engine game today I'd go for Blood), Commandos, Men in Black: The Game (awful but I liked it back then), Alien Rampage, Resident Evil 2 (first big gaming scare), Diablo 2, Starcraft & Age of Empires 2 (I've always sucked at RTS games), Big Red Racing (we played it split screen and don't think ever finished a race, we just crashed onto each other like morons 'till someone exploded lol good times).
I'm sure I missed a few.
We also had a Genesis emulator and a bunch of roms. The Indiana Jones game was fun to play. I was obsessed with those films back in the good ol'. General Chaos also deserves a mention, so many 2-player laughs shared. Oh and the first ToeJam & Earl game, more shared laghs. Wish the sequel was an evolution of the formula instead of a side-scrolling platformer.