I don't think consciousness and matter (or energy, or the physical, etc) are in essence different things. I think these words refer to different perspectives rather than different things. When looking a body or a brain, one can see matter, but not consciousness. But we project a 1st person perspective onto that 3rd person matter, and create a duality in which a person is at the same time mind (1st person) and matter (3rd person). I don't think mind is more mysterious than matter, since I think they are, in essence, the same nature. The mystery for me is existence itself, which includes 1st and 3rd person perspective as two sides of the same coin. One of the limitations I see in scientific method is that, even though it can find laws and predict the behaviour of matter, it can't reach the essence of matter itself.