Originally Posted by Jimiam
5htp did not work for me. Garbage. I won't spend my money on it.
I tried it very recently for two weeks (I even started a thread on it that is somewhere below) - with mixed results. I think when I took some doses, I could feel a lift in mood (nothing really dramatic, though) - but other doses seemed to work less well. But I realized recently that, even if my mood isn't lifted dramatically, it may have some value in at least stopping me from hitting the lowest of lows as my mind/body continue to withdraw from Effexor. So even though I might not feel really happy or anything - I think I've felt better than I would be feeling if I weren't taking it.
Plus I wasn't taking the "maximum" dose - I was only taking 200mg/day, while certain "experts" recommend taking up to 300mg/day (or even more in a few cases).
Anyway, I switched to tryptophan a couple of days ago. Seems like I "feel" it working some (but again, nothing really dramatic). I can't really say at this time if it is working better than 5-htp or not.
One has to really experiment with doses and dosing schedules, I imagine. People are different in what doses/dose schedules work best for them. I had been taking all of my daily dose of 5-htp in 2 divided doses, but w/ tryptophan I'm experimenting with spreading my daily dose out to 3 times per day. I'm also trying to get an idea of how much I should take a day - should I take 1.5grams per day (3 tablets), or more?
Then, the experts say that you should take 5-htp or tryptophan with fruit juice (or some simple sugar) to help it absorb into the brain better. (Supposedly the "insulin release" that comes from the sugar helps with escorting these amino acids into the brain.) Then they say that you should be taking B-complex/B-6 to help convert the aminos into serotonin. So there are a lot of "ways" that you can take this to see if your body utilizes it better.
(But there is a caution about 5-htp. See the other thread.)