Social Anxiety Forum - View Single Post - Zoloft (sertraline) [SSRI]

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post #14 of (permalink) Old 03-01-2010, 02:09 PM Thread Starter
Helena_SAS
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Join Date: May 2012
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First three days were amazing, the rest was awful


(Copied over from old review system)

Posted by rustybob
Social Anxiety Background
Had social anxiety pretty much forever from growing up in a racist town. Definitely not the textbook social anxiety case, as I did have friends, played team sports, worked since I was 10 years old, did sales jobs, etc etc. I never realized I had it until I finally decided to fix my sleep problems.

My whole life I've been unable to get more than 1.5 hours straight of sleep (unless I was sick). So even though I got 8 hours I still felt like crap. This is what initially got me into trying to figure out what's wrong with me. Once I seen the list of symptoms for seratonin deficiency I knew that was my problem. My whole life have suffered from a lack of energy and motivation.

Other Treatments
Ativan (although this was initially prescribed for sleep)
Valium (not obtained through a doctor, worked great though)
Wellbutrin (Still using, working great with Remeron)
Remeron (Amazing, has me feeling like a normal person)
5-HTP (Helped mood slightly, sleep was just as bad due to crazy nightmares)

Treatment Experience
Zoloft was the first antidepressant I tried. I still to this day wonder if I might be bipolar, and the first three days of Zoloft are a good reason why. With the current treatment I'm on, 300mg of Wellbutrin and 45mg of Remeron, I haven't had any swings like I did before. There have been times where I'd go 3-4 weeks full of energy and with no social anxiety, to times of depression for no real reason, and others with basically no feeling at all.

Back to those first three days... absolutely amazing. They were better than any of the possibly manic swings I'd had before. My jaw was getting sore from how much I was smiling. Sleep was great. Social anxiety non-existant. Then reality set in. The next week I started to turn into a zombie, and the sexual side effects started to kick in.

I did decide to keep on trying Zoloft to see if the side effects would wear off over time, and we also increased my dosage from the starting 25mg to 50 and 75mg. For a while I was sleeping 14 hours a day. For most of the time I was at the higher dosage, if someone called me up and said "lets go out" there'd be no problem, but the anxiety was so bad that I couldn't get myself to call anyone myself. I'd say in general I was feeling pretty good about myself, but didn't want to be around anybody. I'd say Zoloft would work great if I was someone who was going through a tough time and needed something to help me through it. However, I've been screwed up my whole life so it was really bad for me.

The sexual side effects were just brutal. During the first three days it kicked my libido into overdrive. Then it killed it for a few weeks. But the worst part of all was when it kicked it back into overdrive, but left me impotent to the point that neither Viagra nor Levitra helped. Made it about as hard to orgasm as the times I've done MDMA.

For me at least, it seems that any drug that blocks seratonin reuptake always ends badly for me (see my Effexor experience), although norepinepherine and dopamine reuptake blocking is fine. A combination of Remeron and Wellbutrin turned out to be exactly what I needed, and that combination has completely changed my life.
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