I have been taking lexapro for two months now and the first week I felt so amazing and was taking it at night. I didn't sleep that much but I felt so awake. I asked my nurse and she said to take it in the morning since I wasn't sleeping. I know that a lot of it was getting new medication in my system so I was acting differently. About a week or two ago I noticed it really wasn't working as well on only 10mg so she upped it to 20mg. But I would like some opinions on when to take it. I fee so tired during the day. I've taken it in the morning and at night and I just can't tell which is best. I know everyone reacts to meds differently. Part of my problem other than depression and anxiety is having low energy. Does anyone have any opinions that might help me?