I just started taking 5-htp today. I did my best to research the dosage. I was told to start off at 100mg.. unfortunately it's initial effect has not been great. I feel more immobile than I do when I'm under an anxiety attack. Perhaps it's WAY too high of a dosage to start at. I feel trying the 25 mg may be a lot better for me.. Anything than what I feel right now!! (more anxious than I originally was!!