Manerix (moclobemide)
Description:
Moclobemide (sold as Aurox, Manerix) is a drug primarily used to treat depression and social anxiety. Although clinical trials with the medicine began in 1977, it is not approved for use in the United States. Moclobemide is a reversible inhibitor of monoamine oxidase A (RIMA),[1] a type of monoamine oxidase inhibitor (MAOI), and acts on epinephrine (adrenaline), norepinephrine (noradrenaline), serotonin, and dopamine. Unlike standard MAOIs, possible side effects do not include cardiovascular complications (hypertension) with encephalopathy, liver toxicity or hyperthermia.
More Info: http://en.wikipedia.org/wiki/Moclobemide
RevolutionHealth.com Ratings:
http://www.revolutionhealth.com/drugs-treatments/rating/aurorix-moclobemide
More Info: http://en.wikipedia.org/wiki/Moclobemide
RevolutionHealth.com Ratings:
http://www.revolutionhealth.com/drugs-treatments/rating/aurorix-moclobemide
Moclobemide
Shared by dss on Dec 3rd, 2008
5 out of 6 people found this treatment experience helpful:
Treatment Experience
Well I started on Moclobemide 150mg and over about 4 weeks brought myself up to 600mg dose.
The Positive - No side effects at all! Seems strange but I had absolutely no kind of side effect starting or being on this med (Will be stopping it shortly).
The Negative - No noticeable help for SA. I really felt like it did nothing for me. Even changing doses from 600mg back down to 150mg I noticed no change.
I've read a few reports of it helping people for depression but for SA which is what I was using it for it did not help. It could be that I didn't give it enough of a chance but I felt a little over 6 weeks was a good enough trial to notice some kind of benefit.
Well I started on Moclobemide 150mg and over about 4 weeks brought myself up to 600mg dose.
The Positive - No side effects at all! Seems strange but I had absolutely no kind of side effect starting or being on this med (Will be stopping it shortly).
The Negative - No noticeable help for SA. I really felt like it did nothing for me. Even changing doses from 600mg back down to 150mg I noticed no change.
I've read a few reports of it helping people for depression but for SA which is what I was using it for it did not help. It could be that I didn't give it enough of a chance but I felt a little over 6 weeks was a good enough trial to notice some kind of benefit.
Was this treatment experience helpful to you?
Manerix (moclobemide)
Shared by michellejl on Nov 15th, 2008
8 out of 12 people found this treatment experience helpful:
Treatment Experience
My experience with Manerix was very positive.
I had tried almost every other kind of antidepressant, and this was the only one that worked for me.
It did not help a lot with SA symptoms themselves, but I went from having severe depression to feeling good about life again. I had a lot more motivation to work on SA, go to CBT group therapy, go to support groups, leave the house, talk to people etc.
I was on an average dose (I forget how much!)and when my dr. increased it while I was going through a rough patch I started having hypomanic symtoms. She tried me on lamictal as an experiment and it was life changing for me!
While Manerix was very helpful to get me through very bad depression with no side effects (some drug restrictions like cough medicine, etc) I think I needed a mood stabilizer as I have not been depressed since and it has been a couple of years.
My experience with Manerix was very positive.
I had tried almost every other kind of antidepressant, and this was the only one that worked for me.
It did not help a lot with SA symptoms themselves, but I went from having severe depression to feeling good about life again. I had a lot more motivation to work on SA, go to CBT group therapy, go to support groups, leave the house, talk to people etc.
I was on an average dose (I forget how much!)and when my dr. increased it while I was going through a rough patch I started having hypomanic symtoms. She tried me on lamictal as an experiment and it was life changing for me!
While Manerix was very helpful to get me through very bad depression with no side effects (some drug restrictions like cough medicine, etc) I think I needed a mood stabilizer as I have not been depressed since and it has been a couple of years.
Was this treatment experience helpful to you?
Manerix and I
Shared by RainbowElf on Nov 23rd, 2008
7 out of 14 people found this treatment experience helpful:
Treatment Experience
I started on a slow increase of a 150mg per fortnight, but had to stop before i got to the right dose as it made me vomit.
When I consulted the doctor we agreed on a faster increase to try and combat this.
I started on the low dose of 150 again and within 3 weeks had gotten up to 600mg. Which as of yet is my final dose.
It has helped me in the sense I can do the shopping a bit better although I do have a terrible shake from the medication. This started as restless legs, then restless arms and now I have a continuous shake.
I think for now I can cope if it means been able to control the anxiety a bit better. The sickness has not returned yet, so I guess sometimes you might need a quicker increase.
I started on a slow increase of a 150mg per fortnight, but had to stop before i got to the right dose as it made me vomit.
When I consulted the doctor we agreed on a faster increase to try and combat this.
I started on the low dose of 150 again and within 3 weeks had gotten up to 600mg. Which as of yet is my final dose.
It has helped me in the sense I can do the shopping a bit better although I do have a terrible shake from the medication. This started as restless legs, then restless arms and now I have a continuous shake.
I think for now I can cope if it means been able to control the anxiety a bit better. The sickness has not returned yet, so I guess sometimes you might need a quicker increase.
Was this treatment experience helpful to you?
Recommended Book
Search Treatments
About Treatment Experiences
The individual experiences about treatment for social anxiety disorder (social phobia) are not a substitute for medical advice.
You should always consult a qualified health care professional before beginning, changing or stopping a treatment.
