On the forums we hear over and over again about, "everyones different and reacts a different way to every AD."
Maybe a bit true, but way over exadurated IMO. Last time I checked were are all of the same species.
I hear much about
: "50Mgs of Zoloft didn't work for me." Well no kidding, a 90 LBS person could handle such a tiny dosage and not get relief from SA or depression. 50Mgs of Zoloft is like Placebo. Better to take nothing at such a low dosage.
Then you get this one: "I had bad side effects so I stoped it," only to discover later that this person was only on the drug for 5 weeks not even giving the body time to adjust.
Are we all having different specialized allergic reactions to AD's nearly 90% of the time? I don't think so. I think it's usually wrong dosage or not enough time given in many cases.
I just took an advil for my headache. If you take an Advil will it make you sick? Not really in almost every case.
As far as efficacy, I have found that once a person has burned out on an SSRI or SNRI or Tricyclic that switching to another in the same class is always met with lack luster results. Matters not that it's Lexipro this time and was Prozac last time. If you really watch what people are reporting you will see the above is true.
Example: Bob takes Lexapro with effective results for 4 years and then it slowly stops working. He must change meds so he changes to Paxil, both SSRI's. The result? I have $500 that says Bob finds little relief from Paxil or any SSRI at least not for long.
If Bobs first SSRI was Paxil then he would have found it effective. You can switch it either way. Then people go from SSRI to another SSRI until none are even left and get no relief. I Here it all the time on the forum. This person never thinking, "I'm burned out of this class of drugs, lets try an SNRI to get relief." Odds are better that change of class will be much more activating and work better.
It reminds me of putting sour milk in the fridge, then going back two days later expecting it to be fresh.