Social Anxiety Support

ecotec83 · 11-23-2009, 08:21 PM

I'm currently taking 10mg of Lexapro daily but was also taking wellbutrin but found it was not agreeing with me even at a small dose(urinary retention). I like the mild energy and elevated mood that increasing dopamine and norepinephrine levels caused. While the lex is working great i think the 2 drug approach was the magic spot for me.

Are there any other drugs similar to wellbutrin that are not addictive, have a low side effect profile and fairly easy to get?

db0255 · 11-23-2009, 08:45 PM

Remeron ups dop/nor but I don't think it does so like Wellbutrin. Cymbalta and Effexor are SNRIs, but don't work on dopamine.

To hit dopamine like Wellbutrin you got to either drop the Lexapro, go on Zoloft or an MAOI. Or try a stimulant.

Cocaine is also an SNDRI.

martyboi · 11-23-2009, 08:56 PM

u might try a low dose of selegiline. it can have effects like amphetamines but milder. It works mainly on dopamine at low doses and serotonin at higher doses. so if u keep the dose low, it shouldn't interact badly with the lexapro. I've heard of people using this combo with success

jim_morrison · 11-23-2009, 08:57 PM

SNRI's will actually target dopamine to an extent since anything that blocks noradrenaline reuptake is going to also boost dopamine neurotransmission in the frontal cortex. Effexor in particular can also directly block the dopamine reuptake pump at high doses.

I agree that zoloft can block dopamine reuptake weakly, although most people on it seem to claim that it causes typical SSRI side effects such as apathy and sexual dysfunction so I wouldn't be too confident in it boosting dopamine to any great extent within the usual dose range.

Remeron can increase dop/nor however I doubt it would cause the mild energy that he got/desires from wellbutrin, since remeron is also such a potent antihistamine.

Prozac is an option.

ecotec83 · 11-23-2009, 09:06 PM

Thanks for the advice. I think i'm going to stay on my lex but i will talk to the doctor next time i see him to see if he has any suggestions.

jakeforpresident · 11-23-2009, 09:23 PM

50-200mg dose of Solian

ecotec83 · 11-23-2009, 09:44 PM

Quote:

Originally Posted by jakeforpresident

50-200mg dose of Solian

From what i can tell it is not approved for use in Canada or the U.S. Seems to be available in Europe though.

jakeforpresident · 11-24-2009, 04:11 PM

It can be purchased online for a very reasonable price. I plan on getting some myself for sexual side effects or even the mood enhancement.

crayzyMed · 11-24-2009, 04:37 PM

Sulpiride works the same as solian in blocking presynaptic receptors and is available in the US.

11-23-2009, 08:21 PM	#1 (permalink)
ecotec83 Status: Ascending from the dark Join Date: Sep 2009 Location: Belleville, Ontario, Canada Gender: Male Age: 26 Posts: 584	Wellbutrin replacement I'm currently taking 10mg of Lexapro daily but was also taking wellbutrin but found it was not agreeing with me even at a small dose(urinary retention). I like the mild energy and elevated mood that increasing dopamine and norepinephrine levels caused. While the lex is working great i think the 2 drug approach was the magic spot for me. Are there any other drugs similar to wellbutrin that are not addictive, have a low side effect profile and fairly easy to get? __________________ ~Our greatest battles are those with our own mind.~

11-23-2009, 08:57 PM	#4 (permalink)
jim_morrison Status: Super Moderator Join Date: Aug 2008 Location: Australia Gender: Male Age: 23 Posts: 1,298	SNRI's will actually target dopamine to an extent since anything that blocks noradrenaline reuptake is going to also boost dopamine neurotransmission in the frontal cortex. Effexor in particular can also directly block the dopamine reuptake pump at high doses. I agree that zoloft can block dopamine reuptake weakly, although most people on it seem to claim that it causes typical SSRI side effects such as apathy and sexual dysfunction so I wouldn't be too confident in it boosting dopamine to any great extent within the usual dose range. Remeron can increase dop/nor however I doubt it would cause the mild energy that he got/desires from wellbutrin, since remeron is also such a potent antihistamine. Prozac is an option. __________________ Warning: I am not a trained medical professional. Any information provided by me is based on my own personal experiences and research and is not intended to be used as professional medical advice. Please contact a medical professional before taking any action that may be discussed on this board.

11-23-2009, 09:06 PM	#5 (permalink)
ecotec83 Status: Ascending from the dark Join Date: Sep 2009 Location: Belleville, Ontario, Canada Gender: Male Age: 26 Posts: 584	Thanks for the advice. I think i'm going to stay on my lex but i will talk to the doctor next time i see him to see if he has any suggestions. __________________ ~Our greatest battles are those with our own mind.~

11-24-2009, 04:37 PM	#9 (permalink)
crayzyMed Status: The Power Of Nature Join Date: Nov 2006 Location: Belguim Gender: Male Age: 21 Posts: 1,143	Sulpiride works the same as solian in blocking presynaptic receptors and is available in the US. __________________ Disclaimer: Do not ever attempt the same thing i am doing, this is all very experimental and could very well damage your health.

11-23-2009, 08:45 PM	#2 (permalink)
db0255 Status: SAS Member Join Date: Jul 2009 Location: Durham, NC Gender: Male Posts: 434	Remeron ups dop/nor but I don't think it does so like Wellbutrin. Cymbalta and Effexor are SNRIs, but don't work on dopamine. To hit dopamine like Wellbutrin you got to either drop the Lexapro, go on Zoloft or an MAOI. Or try a stimulant. Cocaine is also an SNDRI.

11-23-2009, 08:56 PM	#3 (permalink)
martyboi Status: SAS Member Join Date: Sep 2009 Posts: 111	u might try a low dose of selegiline. it can have effects like amphetamines but milder. It works mainly on dopamine at low doses and serotonin at higher doses. so if u keep the dose low, it shouldn't interact badly with the lexapro. I've heard of people using this combo with success

11-23-2009, 09:23 PM	#6 (permalink)
jakeforpresident Status: social revolutionist Join Date: Sep 2009 Location: Montana Gender: Male Age: 20 Posts: 146	50-200mg dose of Solian

11-24-2009, 04:11 PM	#8 (permalink)
jakeforpresident Status: social revolutionist Join Date: Sep 2009 Location: Montana Gender: Male Age: 20 Posts: 146	It can be purchased online for a very reasonable price. I plan on getting some myself for sexual side effects or even the mood enhancement.