The things i'm trying and going to try

[Medline]

Originally Posted by crayzyMed

Thx for your response.
I have experience with drugs (i used to take MDMA twice a week for 2 years), i also have some experience with amphetamine so i do know what kind of insomnia they could cause).
I will keep benzo's at hand to let me sleep, I will also order cyproheptadine. Its 5HT2A antagonism is also of intrest to me.

I have done an experiment like this with sreet amphetamine before but it didnt really work in normal doses (10mg) and made me paranoid, I've also tried MDPV in the past but it made me waay to paranoid and intensified my anxiety, i beleive that one is bad for anxiety but better for ADHD like conditions.

Are you planning on taking desoxy again medline? I did read it worked for you for a while.

How do you know the exact dose (10mg) of street amphetamine? I will go the low dose selegiline + methylphenidate route and add clonazepam + carvedilol. I have everything except for the Ritalin, but my Pdoc promised to prescibe it next time and I don't need high doses because of the mao-b inhibition from the selegiline.

[crayzyMed]

Originally Posted by Medline

How do you know the exact dose (10mg) of street amphetamine? I will go the low dose selegiline + methylphenidate route and add clonazepam + carvedilol. I have everything except for the Ritalin, but my Pdoc promised to prescibe it next time and I don't need high doses because of the mao-b inhibition from the selegiline.

I dont, i know taking street amphetamine was a very bad idea, i didnt even have a scale to weigh it out so i took just a small bit. This time i'm going to buy a scale tough, the chemicals i order are also going to pure so i would allways know my dose.

Anywhay good luck with your meds

[Vini Vidi Vici]

Originally Posted by Medline

How do you know the exact dose (10mg) of street amphetamine? I will go the low dose selegiline + methylphenidate route and add clonazepam + carvedilol. I have everything except for the Ritalin, but my Pdoc promised to prescibe it next time and I don't need high doses because of the mao-b inhibition from the selegiline.

oh i took that combo once.... the EMSAM patch, well like 6 mg of selegiline a day, plus Extended release ritalin --(concerta).....and it worked pretty awesomely for my concentration abilities. I would sit in front of the computer for 6 hours, not kidding, 6 hours, wouldnt move at all.....but it seemed as if my social anxiety wasn't really helped that much. So sometimes i supplemented (cough) with alcohol....that was pretty awesome. not much social anxiety then. A really nice combination...until i got tolerant to the ritalin. Do you think, possibly, maybe adderral would be a better choice than the ritalin? cuz according to RocknRoll...it would always be more potent, and you won't get tolerant as fast cuz its a releaser, not just a DAT blocker...i seemed to get tolerant to ritalin in 1-2 weeks. unfortunately......oh and i dunno if theres some other thread somewhere, but how exactly does DXM block adderall tolerance?

[crayzyMed]

Originally Posted by Vini Vidi Vici

oh i took that combo once.... the EMSAM patch, well like 6 mg of selegiline a day, plus Extended release ritalin --(concerta).....and it worked pretty awesomely for my concentration abilities. I would sit in front of the computer for 6 hours, not kidding, 6 hours, wouldnt move at all.....but it seemed as if my social anxiety wasn't really helped that much. So sometimes i supplemented (cough) with alcohol....that was pretty awesome. not much social anxiety then. A really nice combination...until i got tolerant to the ritalin. Do you think, possibly, maybe adderral would be a better choice than the ritalin? cuz according to RocknRoll...it would always be more potent, and you won't get tolerant as fast cuz its a releaser, not just a DAT blocker...i seemed to get tolerant to ritalin in 1-2 weeks. unfortunately......oh and i dunno if theres some other thread somewhere, but how exactly does DXM block adderall tolerance?

There are a few anecdotal reports of memantine blocking amphetamines tolerance. Other NMDA antagonists should also work like DXM. In my own experience amphetamine completely cures me of social anxiety while ritalin and alcohol dont. I'm talking about recreational doses tough as i've never taken adderall (in europe we dont have amphetamines).

[Vini Vidi Vici]

yeah ive always thought that was so unfortunate. no adderral in europe....i mean its so weird how some medications are approved in some places and not in others. yeah i had the same experience....taking Concerta, i had more social anxiety..taking adderall, i had less social anxiety. well at least for a couple weeks. but when i took DXM with the Adderrall, it made the adderral work a whole lot better...and took away a ton of the anxiety and tolerance and insomnia issues. and DXM isnt a very clean NMDA antagonist anyways....with a better or stronger one, like alot of Memantine, amphetamines would be pretty sweet. but arent they both neurotoxic? some dudes did this study, they gave mice adderral, and weeks later, the mice still had deficits in brain dopamine levels. and after chronic administration, the mice showed clear motor deficits compared to the control mice. maybe it would be a good idea to take amphetamines with an MAO-B inhibitor....i guess that might be one cause of the possible neurotoxicity....either dopamine being broken down into MPP+ or whatever it is, or the other theory that adderral breaks down into free radicals

[crayzyMed]

Originally Posted by Vini Vidi Vici

yeah ive always thought that was so unfortunate. no adderral in europe....i mean its so weird how some medications are approved in some places and not in others. yeah i had the same experience....taking Concerta, i had more social anxiety..taking adderall, i had less social anxiety. well at least for a couple weeks. but when i took DXM with the Adderrall, it made the adderral work a whole lot better...and took away a ton of the anxiety and tolerance and insomnia issues. and DXM isnt a very clean NMDA antagonist anyways....with a better or stronger one, like alot of Memantine, amphetamines would be pretty sweet. but arent they both neurotoxic? some dudes did this study, they gave mice adderral, and weeks later, the mice still had deficits in brain dopamine levels. and after chronic administration, the mice showed clear motor deficits compared to the control mice. maybe it would be a good idea to take amphetamines with an MAO-B inhibitor....i guess that might be one cause of the possible neurotoxicity....either dopamine being broken down into MPP+ or whatever it is, or the other theory that adderral breaks down into free radicals

Those studies allways take huge doses, i dont think it would be any problem when taking low therapeutic doses, but i havent looked true all those studies, just saw a discussion about this before. I tought memantine had some neuroprotective properties too.
I havent seen many ppl recommending ritalin for anxiety, lets see wheter it works for medline, if it doesnt ritalin is officially crap for anxiety...

[Medline]

Originally Posted by crayzyMed

Those studies allways take huge doses, i dont think it would be any problem when taking low therapeutic doses, but i havent looked true all those studies, just saw a discussion about this before. I tought memantine had some neuroprotective properties too.
I havent seen many ppl recommending ritalin for anxiety, lets see wheter it works for medline, if it doesnt ritalin is officially crap for anxiety...

Alone, low dose Ritalin + Selgiline might improve social drive (and other things) but could make anxiety even worse, therefor I add clonazepam + carvedilol.

[crayzyMed]

Originally Posted by Medline

Alone, low dose Ritalin + Selgiline might improve social drive (and other things) but could make anxiety even worse, therefor I add clonazepam + carvedilol.

That could work, keep us updated.

[Medline]

Originally Posted by Freesix88

I'm sure Medline will do well with Ritalin. For me Ritalin is a wonder med. If I take 10 mg and wait for half an hour my anxiety and depression mostly disappears. The Clonazepam also helps with anxiety but mostly with OCD and general anxiety. It doesn't boost my social drive like Ritalin does. Clonazepam with Ritalin is totally sweet. They should prescribe Ritalin more for Social anxiety. It's a really safe med too, but there are always people that have to abuse it (crush it and snort it) so that won't happen I'm afraid. Anything that's slightly abusive the goverment doesn't like. (except ciggies and alcohol [I already pay my taxes idiots ) I hate that generalization that stimulants increase anxiety. This is not the case at all for me. Note: I also take Cymbalta. Be careful with selegiline and ritalin it's really really potent this combination.
I once did 5 mg selegiline with 10 - 15 mg (I don't know it exactly anymore) and I expierenced the OD symptoms that Medline describes in this thread. I thought I was going to die.

I'll start low with 5mg Selegiline and 2,5mg Ritalin, measure my blood pressure and heart rate regularly, increase doses slowly just if necessary and have clonazepam and carvedilol (+ haloperidol) to be on the safe side.

Originally Posted by Freesix88

Anyway good luck CrazyMed (you are really a bit crazy with a list like that haha j/k)

Some smart people on this people that will help you. Stay away from drugs that induce neurotoxicity like RocknRoll714 said. Buspar can be interesting at 120 mg. Don't do crazy combinations man.

I didn't want to be the first person who calls CrazyMed a little bit crazy (no offense ), but please slow down somewhat . And yes... I'm crazy too.

[crayzyMed]

Yes i am a bit crazy, i also love partying too much lol
Being crazy is good!

I know the things i'm trying are a bit radical but it want to completely kill social anxiety. And i'm stubborn
I will try things seperate first. I know enough pharmacology to not come up with dangerous combinations.

Also i did try ritalin + GHB/Ritalin + xanax and ritalin + clonazepam in the past without any succes. I didnt mention it as my anxiety seems a bit hard to fix... so there's a big chance those combo's will work perfectly for many others.

I'm going to be the first person in history trying to daily take a serotonin releaser

[Vini Vidi Vici]

Originally Posted by Medline

I'll start low with 5mg Selegiline and 2,5mg Ritalin, measure my blood pressure and heart rate regularly, increase doses slowly just if necessary and have clonazepam and carvedilol (+ haloperidol) to be on the safe side.


I didn't want to be the first person who calls CrazyMed a little bit crazy (no offense ), but please slow down somewhat . And yes... I'm crazy too.

RocknRoll found this one article that talked about how loperamide and haloperidol might cause neurotoxic effects on brain dopaminergic cells and stuff.....that the only reason loperamide doesnt cause parkinsons disease or other stuff is cuz it doesn't cross the blood brain barrier. and as for haloperidol, i mean it causes so many parkinsonian type symptoms anyway at high doses.....what if it actually is causing parkinsons' disease.....but the side effects are labeled "EPS" instead. that would be so unfortunate......poor schizophrenic people
http://www.springerlink.com/content/1a5dbp719afntvdq/




in regards to taking medications i think i might have a history of being almost as crazy as CrazyMed..but i had to change my views on medications when i had the interaction thingy...like now im obsessive about every medication...i dunno which is better. i actually was taking about 6 different things, and was planning on taking quite a bit more different things....i ordered stuff online, and was gonna like pop it all without regard.....i think god saved me from disaster lol.....my online order eventually came, but i was too scared to take any of it except the agomelatine....but my hope for the future is too be extremely crazy. ive always wanted to be such....but im too depressed to be crazy...hopefully soon i will be crazy. i look forward to it

[rocknroll714]

Nobody can top me.

I took Nardil and MDMA together and lived to tell about it!

[Medline]

Originally Posted by rocknroll714

Nobody can top me.

I took Nardil and MDMA together and lived to tell about it!

I remember too well, also your Nardil + SSRI (I think it was Paxil) "experiment". You definitely won the "who is more crazy contest". No offense... . Luckily it seems you have slowed down somethat.

[crayzyMed]

Haha, rocknroll deifinatly is the winner

I received my "mimosa hostilis" by the way, so the first experiment i'm gonna conduct is with daily low doses of DMT

I also got some salvia but thats for other purposes lol.

[euphoria]

Originally Posted by crayzyMed

Haha, rocknroll deifinatly is the winner

I received my "mimosa hostilis" by the way, so the first experiment i'm gonna conduct is with daily low doses of DMT

I also got some salvia but thats for other purposes lol.

Are you not worried about taking a 5-HT2B agonist regularly? I'm guessing DMT is a strong agonist at that receptor, like other psychedelics.

Salvia... When I tried it, it was a very unpleasant experience.

[crayzyMed]

Originally Posted by euphoria

Are you not worried about taking a 5-HT2B agonist regularly? I'm guessing DMT is a strong agonist at that receptor, like other psychedelics.

Salvia... When I tried it, it was a very unpleasant experience.

I can take agomelatine for its 5HT2B antagonism.

I like the short duration of salvia, LSD was the worst experience of my life.. It lasted from 2 hours afternoon till the next morning 8 o clock. But it did have a good effect on my life afterwards tough.
So if it goes wrong it will be over quick

[euphoria]

Originally Posted by crayzyMed

I can take agomelatine for its 5HT2B antagonism.

Agomelatine has a half life of < 2 hours, it won't work.

I like the short duration of salvia, LSD was the worst experience of my life.. It lasted from 2 hours afternoon till the next morning 8 o clock. But it did have a good effect on my life afterwards tough.
So if it goes wrong it will be over quick

LSD is probably a lot more enjoyable than salvia.

[crayzyMed]

Originally Posted by euphoria

Agomelatine has a half life of < 2 hours, it won't work.



LSD is probably a lot more enjoyable than salvia.

Hmm, will see i gotta try everything

About that 5HT2B agonis, i'l look for ways how to solve it...

[crayzyMed]

I also stopped taking the sulpiride as it didnt seem to do any good, the first 2 days it gave me more energie but after that it just made me tired, tried both 25mg and 50mg doses.

I've just ordered some Desoxypipradrol to experiment with it, as adding a dopamine releaser to MDAI would make it neurotoxic.
The only thing i've got allready is mimosa hostilis (DMT) i will extract it this evening so i can do my first experiment tomorrow. Ppl have used it as an antidepressant in low doses before and DMT hasnt got any tolerance issues.

I've got, a few things coming my whay, i'm not going to add them all togheter but will experiment with a few things to work out what works best.

DO NOT TRY THIS AT HOME! I AM DOING CRAZY EXPERIMENTS!

[jim_morrison]

Originally Posted by euphoria

Are you not worried about taking a 5-HT2B agonist regularly?

He's got a point, it's like you may aswell be taking Fen-Phen.