Switching MAOIs - Nardil to Moclobemide - Do i have to washout? - Social Anxiety Forum
 
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post #1 of 9 (permalink) Old 04-20-2017, 07:22 PM Thread Starter
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Exclamation Switching MAOIs - Nardil to Moclobemide - Do i have to washout?

Dear SAS friends,
Sorry ive been away for a while, due to catatonic levels of depression.

So ive been on Nardil for about 3 weeks, and now have Moclobemide.
Both MAOIs, however Nardil = irreversible, unselective and Moclobemide = reversible, selective (RIMA).

Ive searched everywhere but theres NOTHING on the subject of switching from Nardil to Moclob. Not even on wikipedia or the Moclobemide MIMS pamphlet does it mention other MAOIs and Moclobemide even being contraindicated or interacting.

I dread thinking about the usual 2 week washout period, i doubt I will have to wait that long.

Do i have to wait at all? How long until i can start taking moclobemide? I took my last Nardil doses yesterday.

Thanks everyone so much,
Ill get back to you all from my last few threads asap, ive just been suicidally catatonic and unable to even use a computer since i last posted.
Dorian

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post #2 of 9 (permalink) Old 04-20-2017, 10:59 PM
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i did switch from nardil to parnate and back again, twice, with no washout period but sorry hve no idea about a switch to moclobemide. I wouldn't have thought its that common to switch from maoi to a rima.

3 weeks isn't very long for nardil - is it just too much for you to continue ?


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post #3 of 9 (permalink) Old 04-21-2017, 03:54 AM
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Why would you even want to make this switch?

Moclobemide doesn't have a great reputation for depression let alone severe depression where as Nardil is supposed to be one of the most potent second choice medications after SSRIs fail.
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post #4 of 9 (permalink) Old 04-21-2017, 04:57 AM Thread Starter
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i did switch from nardil to parnate and back again, twice, with no washout period but sorry hve no idea about a switch to moclobemide. I wouldn't have thought its that common to switch from maoi to a rima.

3 weeks isn't very long for nardil - is it just too much for you to continue ?
Hi thank u for ur reply,
Ive been on Nardil before in the past and it didnt really work... Either made me highly manic, extremely angry or just numb..
Its because i have borderline PD There is no cure.
Mood stabilisers didnt really help either when i was on Parnate.

So u had no probs switching between nardil and parnate at all? Im just worried about serotonin issues. I dont know what to do.. I dont know moclobemide well enough to know for sure.

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post #5 of 9 (permalink) Old 04-21-2017, 04:59 AM Thread Starter
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Why would you even want to make this switch?

Moclobemide doesn't have a great reputation for depression let alone severe depression where as Nardil is supposed to be one of the most potent second choice medications after SSRIs fail.
Because ive been on both Nardil and Parnate - because everyone said it would work. But neither of them worked.
So why not try moclob, everyone says it doesnt work. So it will probably work.
(I have borderline PD which makes me a lost cause with no cure when it comes to meds...)

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post #6 of 9 (permalink) Old 04-21-2017, 05:03 AM Thread Starter
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Caedmon? Watertouch? ChopSuey? Etc etc etc Anyone know anything?? I need to start moclob asap. The depression has gone suicidal...
Nardil and parnate didnt work for me, mood stabilisers didnt help much either.
I have an incurable disease called borderline personality... So im sort of got no options left.
Except that *one* but im trying very hard to back away from that edge. Theres only so much more of this life i can take.
Thank u all

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post #7 of 9 (permalink) Old 04-21-2017, 05:04 AM
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Originally Posted by doriangray View Post
Because ive been on both Nardil and Parnate - because everyone said it would work. But neither of them worked.
So why not try moclob, everyone says it doesnt work. So it will probably work.
(I have borderline PD which makes me a lost cause with no cure when it comes to meds...)
Well the positive with Moclobemide is the pretty non existent side effects (in my experience anyway)... hopefully that will be the same for you.
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post #8 of 9 (permalink) Old 04-21-2017, 06:18 AM Thread Starter
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Well the positive with Moclobemide is the pretty non existent side effects (in my experience anyway)... hopefully that will be the same for you.

Thank you mate... I didnt get any sides or care about side effects from Nardil and Parnate. But id put up with any side effects just to get better.
Moclobemide cant be *that* useless, can it? This makes me feel so hopeless.
I thought maybe this time i had a chance

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post #9 of 9 (permalink) Old 04-21-2017, 06:29 AM
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Quote:
Originally Posted by doriangray View Post
Hi thank u for ur reply,
Ive been on Nardil before in the past and it didnt really work... Either made me highly manic, extremely angry or just numb..
Its because i have borderline PD There is no cure.
Mood stabilisers didnt really help either when i was on Parnate.

So u had no probs switching between nardil and parnate at all? Im just worried about serotonin issues. I dont know what to do.. I dont know moclobemide well enough to know for sure.
No i had no problems at all switching between nardil and parnate but know next to nothing about moclobemide, although I cant see it needing 2 weeks wash out - i dont know.

Anyway, hope the switch helps out with your condition.


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