So...help me get prosocial!

[GnR]

So I've been on escitalopram for a little over a month, and it's helping, but not enough. My depression is mostly gone, as well as my GAD. This has helped my SA indirectly, but it is a very miniscule improvement. I would also say I have slightly lower social drive. So here are the meds I'm looking at, in no particular order...

Wellbutrin (although I've heard its effects on dopamine are minor)

Desoxypipradrol (I understand and appreciate the risks)

Ritalin (wouldn't be too hard for me to get ahold of)

Unfortunatly an amphetamine won't be an option for at least six months, as that is how long referral to a pdoc takes in my country.

Anyways, all comments and suggestions are welcome.

[crayzyMed]

Ritalin sucks for SA imo. Desoxy is rated alot better for social anxiety.

[GnR]

Ya, my main concern with desoxy is it's crazy half-life.

[crayzyMed]

Originally Posted by GnR

Ya, my main concern with desoxy is it's crazy half-life.

Yeah thats a bit of a downside with this chemical, however medline seemed to do great on it for some days.

[GnR]

Anyone care to chime in with their ssri+wellbutrin experience?

[db0255]

I became egregiously prosocial for like 7 months on Prozac. It's not just dopamine that makes you prosocial, and I'd argue that it would only make you more social and talkative (there's a difference). Just like alcohol makes you wanna socialize, so does dopamine; the difference with Prozac was that I became extraverted, sought out people, strangers, any tangible thing that could talk back.

Point being: don't limit your options. Play the field.

[Vini Vidi Vici]

SSRI+Wellbutrin was... really good, in a way. It helped raise my desire to socialize, at least up to somewhat near a normal level. It completely counteracted the Sexual Dysfunction, I mean completely....this was proabably the most effective thing it did. It made me care alot more, and i started listening to music, doing stuff, showing interest in stuff, instead of apathy. I wanted to talk to people...Wellbutrin lowered the anxiety, in a Psychological sense. But in a physical sense, Wellbutrin increased anxiety. I think the experience would vary greatly between different individuals....because, I really liked the Wellbutrin. But it was making my OCD worse....but if it wern't for the OCD i probably would have kept taking it. But it does make me agitated...not in a bad way. But in a "I have to do something/drink caffeine/smoke a cigarette/wack off (lol jk) way. Id say for sure, this combo is more helpful than either SSRI or Wellbutrin alone. Of course, it is nowhere near perfect. Too stimulating. But it was still good.

SSRI+Ritalin, for me....i dunno why, but it was GReat for Motivation, depression, and apathy. I can honestly say I was a tad euphoric, and i was ultra-motivated and had meta-cognition. I could think non-stop for hours....and figure out the deepest equations of the universe...and visualize everything perfectly....i was absolutely insane. But weirdly, It did nothing for my SA, at all. I don't know why, but, i was still anxious. Now, i would assume it would help SOME people a whole lot with SA, since its Ritalin, obviously. But it was nowhere near amphetamine in its SA effifacy (unless i combined it with alcohol, in which case, it worked amazingly for everything, including SA).

I wouldnt rule out Ritalin, even though you can see 2 reports of Ritalin not working for SA. I bet the response varies greatly between different people....especially since you are also taking K-pin. since K-pin can be compared to alcohol.......i would assume K-pin + SSRI + Ritalin would work amazingly.

Coincidentally, Tomorrow, im going to my p-doc. Im asking for an SSRI (Luvox) + either Ritalin, Focalin, or Dexedrine. I cannot decide which to get.....for various reasons.

[GnR]

Originally Posted by db0255

I became egregiously prosocial for like 7 months on Prozac. It's not just dopamine that makes you prosocial, and I'd argue that it would only make you more social and talkative (there's a difference). Just like alcohol makes you wanna socialize, so does dopamine; the difference with Prozac was that I became extraverted, sought out people, strangers, any tangible thing that could talk back.

Point being: don't limit your options. Play the field.

Thats very interesting, and I think I've read this about prozac before. Did the effects simply fade away?

[GnR]

Originally Posted by Vini Vidi Vici

SSRI+Wellbutrin was... really good, in a way. It helped raise my desire to socialize, at least up to somewhat near a normal level. It completely counteracted the Sexual Dysfunction, I mean completely....this was proabably the most effective thing it did. It made me care alot more, and i started listening to music, doing stuff, showing interest in stuff, instead of apathy. I wanted to talk to people...Wellbutrin lowered the anxiety, in a Psychological sense. But in a physical sense, Wellbutrin increased anxiety. I think the experience would vary greatly between different individuals....because, I really liked the Wellbutrin. But it was making my OCD worse....but if it wern't for the OCD i probably would have kept taking it. But it does make me agitated...not in a bad way. But in a "I have to do something/drink caffeine/smoke a cigarette/wack off (lol jk) way. Id say for sure, this combo is more helpful than either SSRI or Wellbutrin alone. Of course, it is nowhere near perfect. Too stimulating. But it was still good.

SSRI+Ritalin, for me....i dunno why, but it was GReat for Motivation, depression, and apathy. I can honestly say I was a tad euphoric, and i was ultra-motivated and had meta-cognition. I could think non-stop for hours....and figure out the deepest equations of the universe...and visualize everything perfectly....i was absolutely insane. But weirdly, It did nothing for my SA, at all. I don't know why, but, i was still anxious. Now, i would assume it would help SOME people a whole lot with SA, since its Ritalin, obviously. But it was nowhere near amphetamine in its SA effifacy (unless i combined it with alcohol, in which case, it worked amazingly for everything, including SA).

I wouldnt rule out Ritalin, even though you can see 2 reports of Ritalin not working for SA. I bet the response varies greatly between different people....especially since you are also taking K-pin. since K-pin can be compared to alcohol.......i would assume K-pin + SSRI + Ritalin would work amazingly.

Coincidentally, Tomorrow, im going to my p-doc. Im asking for an SSRI (Luvox) + either Ritalin, Focalin, or Dexedrine. I cannot decide which to get.....for various reasons.

Those are the exact effects I would hope to get out of wellbutrin, too bad you couldn't continue with it. By the way, what type of dosing regime were you using with ritalin? It sounds like it was a good drug for you, and I'm sure it would help me as I'm almost positive I have ADHD.

[Vini Vidi Vici]

Originally Posted by GnR

Those are the exact effects I would hope to get out of wellbutrin, too bad you couldn't continue with it. By the way, what type of dosing regime were you using with ritalin? It sounds like it was a good drug for you, and I'm sure it would help me as I'm almost positive I have ADHD.

i never took "actual" plain instant release ritalin. what i took was Metadate...its an extended realease version of Ritalin...and im pretty sure i took 10mg capsules. Did nothing. felt concentrated for about 45 minutes, then nothing.

So, after taking that for a couple weeks, i started taking Concerta (XXXtended release Ritalin) instead of Metadate. This was the awesome stuff. i took one 36 or 38 mg pill a day...the capsules looked like bullets. Effects would last between 6 and 12 hours..then i would get really depressed. i could not stop thinking, ever. my brain was incapable of stopping. so i guess, to get the same effects one would have to take 10mg ritalin 3-4 times a day....but i always require a high dose of Dopaminergics to get a good effect....many people report Metadate to work for alot longer than it did for me. Also, when i took 10mg Adderral XR for about a month,, the effects would only last for 2-3 hours each dose. Lol. Same thing with Vyvanse, it would only last for 8 hours. somethings wrong with me....like most of these meds are supposed to work all day, not for like 6-8 hours.

Instant release = awesome. at least 3 times a day LOL

[db0255]

Originally Posted by GnR

Thats very interesting, and I think I've read this about prozac before. Did the effects simply fade away?

Yes.

[GnR]

Originally Posted by Vini Vidi Vici

i never took "actual" plain instant release ritalin. what i took was Metadate...its an extended realease version of Ritalin...and im pretty sure i took 10mg capsules. Did nothing. felt concentrated for about 45 minutes, then nothing.

So, after taking that for a couple weeks, i started taking Concerta (XXXtended release Ritalin) instead of Metadate. This was the awesome stuff. i took one 36 or 38 mg pill a day...the capsules looked like bullets. Effects would last between 6 and 12 hours..then i would get really depressed. i could not stop thinking, ever. my brain was incapable of stopping. so i guess, to get the same effects one would have to take 10mg ritalin 3-4 times a day....but i always require a high dose of Dopaminergics to get a good effect....many people report Metadate to work for alot longer than it did for me. Also, when i took 10mg Adderral XR for about a month,, the effects would only last for 2-3 hours each dose. Lol. Same thing with Vyvanse, it would only last for 8 hours. somethings wrong with me....like most of these meds are supposed to work all day, not for like 6-8 hours.

Instant release = awesome. at least 3 times a day LOL

Ya, my rit would be instant release. I guess dosing three times a day isn't a big deal, although then a case could be made for 2-dpmp. Just a couple mgs in the AM and it would last all day. Decision's, decision's....

[Vini Vidi Vici]

Originally Posted by GnR

Ya, my rit would be instant release. I guess dosing three times a day isn't a big deal, although then a case could be made for 2-dpmp. Just a couple mgs in the AM and it would last all day. Decision's, decision's....

why make a descision, when you can have both? !!!! of course monetary supply can eliminate this all-inclusive option, but still. yeah descisions suck....especially when i don't have enough money to get everything...and how do i even know its gonna work, what i buy.

well...the desoxypipradol would probably make you stay up all night, right? and if it didn't work, or you didn't like it, youd be stuck with this expensive chemical that you can't use. Unless of course, you used it with something to block its Adrenergic effects, im not sure if beta blockers and alpha blockers are ok to use with DNRIs..... but then maybe it would be better.

[GnR]

Originally Posted by Vini Vidi Vici

why make a descision, when you can have both? !!!! of course monetary supply can eliminate this all-inclusive option, but still. yeah descisions suck....especially when i don't have enough money to get everything...and how do i even know its gonna work, what i buy.

well...the desoxypipradol would probably make you stay up all night, right? and if it didn't work, or you didn't like it, youd be stuck with this expensive chemical that you can't use. Unless of course, you used it with something to block its Adrenergic effects, im not sure if beta blockers and alpha blockers are ok to use with DNRIs..... but then maybe it would be better.

Hahaha, more is always better. Ya the desoxy certainly isnt cheap. I would probably start off taking 1 or 2 mgs in the morning and see how that effects me. Obviously how much it messes with my sleep is dose dependent, but i don't think it'll be a problem, just based on my work schedule. My average day consists of waking up at 4am, getting in my semi at 5, drive 10-16 hours (probably 12 average), and going home exhausted. I could sleep through the apocalypse lol.

[Vini Vidi Vici]

Originally Posted by GnR

Hahaha, more is always better. Ya the desoxy certainly isnt cheap. I would probably start off taking 1 or 2 mgs in the morning and see how that effects me. Obviously how much it messes with my sleep is dose dependent, but i don't think it'll be a problem, just based on my work schedule. My average day consists of waking up at 4am, getting in my semi at 5, drive 10-16 hours (probably 12 average), and going home exhausted. I could sleep through the apocalypse lol.

dudee man.....that sounds like a sweet job for desoxypipradol. Youd be the best semi driver in existence. So howd you get that job? Did you have to do like training and all that stuff...well i guess if your 23 now, thats time enough to go to college. I hear that now Truck companies are only hiring people with college degrees... it sounds pretty cool, i mean at least, if i had music, a nice stereo, and maybe, like some way to communicate with other people while im driving the semi. Or like Rosetta Stone, so i could learn another language while im driving...lol. Or..dude i just had an amazing idea. Invent an autopilot system..... Then you could earn the money, and do whatever you want for like 10-12 hours....what an amazing situation to be in, if it were possible.

[GnR]

Originally Posted by Vini Vidi Vici

dudee man.....that sounds like a sweet job for desoxypipradol. Youd be the best semi driver in existence. So howd you get that job? Did you have to do like training and all that stuff...well i guess if your 23 now, thats time enough to go to college. I hear that now Truck companies are only hiring people with college degrees... it sounds pretty cool, i mean at least, if i had music, a nice stereo, and maybe, like some way to communicate with other people while im driving the semi. Or like Rosetta Stone, so i could learn another language while im driving...lol. Or..dude i just had an amazing idea. Invent an autopilot system..... Then you could earn the money, and do whatever you want for like 10-12 hours....what an amazing situation to be in, if it were possible.

lol ya if I got some desoxy I would have to paint flames on my truck, install extra bright lights and a louder horn. I'd be blastin by everyone lmao. My dad owns a trucking company so it was an easy in for me. Its alright because once you have your commercial license and some experience, you'll always have something to fall back on that pays decent. I never intended to do it for too long, and its definately a horrible job to do for too long if you have SA. Way too much isolation, so I'll soon be making a change. But I always enjoy driving a 500HP truck that weighs over 100,000lbs. Makes me feel like a big man lol.

[John_in_SF]

I have been taking Celexa plus Wellbutrin since February and they have brought me back from a deep depression. But the W never completely counteracted the sexual side effects of the C so I'm weaning off the latter. I exercise every day and that really seems to keep the depression away.

My social anxiety is not so bad but I'm still a loner. The meds alone haven't changed that.

[GnR]

Thanks for the input John.

[TiMeZuP]

Alcohol never made me feel pro social. It made me feel wayyy more introverted and just want to stair at the wall

[Ehsan]

Originally Posted by GnR

Anyone care to chime in with their ssri+wellbutrin experience?

see below.
interesting!!

Originally Posted by Ehsan

i wanna reveal one of my discoveries here
some of SSRIs inhibit metabolization of Welbutrin which is important to people who havn't accsess to any stimulants.

why?

because liver metabolize welbutrin(bupropion) extensively to hydroxy-bupropion which is completely NRI while welbutrin itself is DRI.

so if you use enough prozac and/or zoloft before,with and after welbutrin it works as a stimulant(DRI). however it's less potent than adderaal,...