I have tried 4 antidepressants:
Effexor XR @ 75 mg: Worked the 1st time, not the 2nd
Cymbalta @ 60 mg: I'm on it right now and it works
Paxil @ 40 mg: Didn't work
Celexa @ 40 mg: Didn't work but I didn't give it enough time
Is there a reason why only the SNRIs work for me or is it just a coincidence? Also they work pretty fast, I could see a difference the very first day I took them. I thought that maybe it's because they act on norepinephrine and dopamine too but then I realized that the Effexor XR only acts as a SSRI at 75 mg.
Well i have the same thing, exactly the same.
SNRI's work great for me whereas the SSRI's worked at the beginning but then they were pretty lethal for me, i was crying, eating, stressed and paxil and lexapro which i had in high doses did nothing for my anxiety, it got so bad i had serotonin overload due to being prescribed a higher dose.
A higher dose of effexor will not do this, in fact 300MG which i am on is really effective.
il tell you what my shrink told me, the good one when i started them in 2006 he said "SNRI's are for people who do not respond to standard SSRI antidepressants" "they are also a safer alternative to MAOI's and old school Tricyclics which have nasty side effects"
there was no weight gain or fatigue on the effexor for me
with the SSRI's all of the ones i tried (lexapro, paxil and prozac/fluox) i had nausea, appetite changes and headaches, such bad headaches
SNRI's work for you, they work for me, they work for other people on this forum too, they are good. i recommend them