Go Back   Social Anxiety Forum > Recovery > Medication


Reply
Old 04-09-2009, 11:37 AM   #1 (permalink)
 
nightwalker's Avatar
 
Status: confused and in pain
Join Date: Nov 2008
Location: Nowhere. I am lost in my soul.
Gender: Female
Posts: 923



Default Prozac or Wellbutrin..

i can't choose.

I have anxiety and depression. My anxiety does not result in panic because whenever i would normal have a panic attack, my dissociation would blur and disintegrate that feeling. I also have depression so I feel brain fog, lack of energy, and no motivcation to do anything. I can not think properly, i slur a lot, and my mind just feels so lazy to do anything that used to be so natural to me. I feel like i just want to do nothing and dissociated while i feel energy in my body that wants to be let out.. I am emotionally numb too. I never feel happiness or sadness.

So my psychiatrist recommended me in taking Prozac, Zoloft, or Wellbutrin.

I hear that Prozac is better for anxiety but it makes some people feel emotionally numb and feel dead and sluggish. I also see that some people have weight gain too. Since i already feel dead, and emotionally numb, is it better than i take Wellbutrin instead?

Wellbutrin, i hear, gives me more energy and motivation. But I hear people say it makes people even more anxious, but this drug helps alot with depression. sometimes people get too much energy and get jittery or tremble..I don't want to be more anxious, but i also really want to have more energy and motivation..since i feel dead and numb already from dissocating and from my depression...

So which one should i take? I don't want to take both. If you recommend that i try out with both, then which should i try out first? Which do you think would help me more? Being more anxious, but without depression, or feeling less anxiety, but feeling more numb and dissociated?

edit: I can't take both because my parents won't let me. so i only need to choose one.. i'm only a teen.
__________________
Before:

After:
nightwalker is offline   Reply With Quote
Old 04-09-2009, 12:04 PM   #2 (permalink)
 
Status: SAS Member
Join Date: Jan 2009
Gender: Male
Posts: 1,794



Default

Both! Why don't you want to take both of them? It's a great combo -- you get serotonin, dopamine and noradrenaline all maxed out.

Prozac happens to moderately inhibit the enzyme (CYP2B6) which converts bupropion into its metabolite, hyrdoxybupropion. Bupropion is far more selective at inhibiting DAT than NAT, while hydroxybupropion is preferential to NAT. By preventing this conversion, you keep the nice dopamine-selective effects of bupropion.

What does the above mean for you? Prozac + Wellbutrin would feel absolutely ****ing amazing. If I had to guess, I would say it'd be similar to a moderate dose of MDMA. It would be literally impossible to have social anxiety, depression or even introversion, I imagine.

I recommend you take Prozac first for a while to get those enzymes inhibited, then start on Wellbutrin.

I have actually snorted Wellbutrin and taken it orally, on different occasions. Snorting bypasses first-pass metabolism in the liver, so presumably a lot more bupropion reaches the brain than hydroxybupropion.

Indeed, snorted Wellbutrin is far more euphoric and fun, while less anxiogenic than swallowing the pill. Noradrenaline-acting stimulants shoot my anxiety through the roof, but when I snorted that stuff I didn't notice any of that.

To those on Wellbutrin: try letting your pills dissolve and absorb under your tongue for a day. You should notice the meds are now a lot smoother and confidence-boosting and less jittery.
euphoria is online now   Reply With Quote
Old 04-09-2009, 12:10 PM   #3 (permalink)
 
nightwalker's Avatar
 
Status: confused and in pain
Join Date: Nov 2008
Location: Nowhere. I am lost in my soul.
Gender: Female
Posts: 923



Default

Quote:
Originally Posted by euphoria View Post
Both! Why don't you want to take both of them? It's a great combo -- you get serotonin, dopamine and noradrenaline all maxed out.

Prozac happens to moderately inhibit the enzyme (CYP2B6) which converts bupropion into its metabolite, hyrdoxybupropion. Bupropion is far more selective at inhibiting DAT than NAT, while hydroxybupropion is preferential to NAT. By preventing this conversion, you keep the nice dopamine-selective effects of bupropion.

What does the above mean for you? Prozac + Wellbutrin would feel absolutely ****ing amazing. If I had to guess, I would say it'd be similar to a moderate dose of MDMA. It would be literally impossible to have social anxiety, depression or even introversion, I imagine.

I recommend you take Prozac first for a while to get those enzymes inhibited, then start on Wellbutrin.

I have actually snorted Wellbutrin and taken it orally, on different occasions. Snorting bypasses first-pass metabolism in the liver, so presumably a lot more bupropion reaches the brain than hydroxybupropion. Indeed, snorted Wellbutrin is far more euphoric and fun than swallowing the pill.
I wish i could, but my parents won't allow that..
so i can only take one.

and personally, i think its unhealthy to have so much chemicals in my body
__________________
Before:

After:
nightwalker is offline   Reply With Quote
Old 04-09-2009, 12:21 PM   #4 (permalink)
 
Medline's Avatar
 
Status: SAS Member
Join Date: Sep 2008
Gender: Male
Posts: 1,866



Default

Even if you could combine you should do it with the low interaction SSRI Zoloft. By the way: Snorting Wellbutrin can easily result in seizures. @nightwalker: Wellbutrin will do nothing for your anxiety (could make it worse), but will give you more energy and motivation at the right dose. Zoloft helps better with SA and I would prefer it over Prozac or any other SSRI except Lexapro (http://www.nlm.nih.gov/medlineplus/n...ory_74676.html)
Medline is online now   Reply With Quote
Old 04-09-2009, 12:46 PM   #5 (permalink)
 
Status: SAS Member
Join Date: Jan 2009
Gender: Male
Posts: 1,794



Default

Quote:
Originally Posted by nightwalker View Post
I wish i could, but my parents won't allow that..
so i can only take one.
Why?

Quote:
and personally, i think its unhealthy to have so much chemicals in my body
Your body already has millions of different chemicals in it. Considering pharmaceuticals are subject to extensive toxicology studies and human trials, it's really not something to be concerned about. Many people are exposed to a lot worse things every day in what they eat, smoke, breathe in, etc.

Talk to your psych about short and long-term side-effects, and read up on it online if it's bothering you.
euphoria is online now   Reply With Quote
Old 04-09-2009, 01:48 PM   #6 (permalink)
 
nightwalker's Avatar
 
Status: confused and in pain
Join Date: Nov 2008
Location: Nowhere. I am lost in my soul.
Gender: Female
Posts: 923



Default

Quote:
Originally Posted by euphoria View Post
Why?
it makes me feel like i'm relying on medication to heal me.. but i only want to take this to speed up recovery while doing therapy. then i wanna get off of them asap[
__________________
Before:

After:
nightwalker is offline   Reply With Quote
Old 04-10-2009, 04:19 PM   #7 (permalink)
 
MavenMI6Agent009's Avatar
 
Status: SAS Member
Join Date: Aug 2004
Location: EL Crapo, Tx
Gender: Male
Age: 25
Posts: 15,183



Default

take wellbutrin you wont gain any weight but you might have some other side effects. zoloft made me eat like a pig I couldnt stop my appetite and gained over 100ibs in two years. Prozac I wouldnt know.
__________________
"The friend who can be silent with us in a moment of despair or confusion, who can stay with us in an hour of grief and bereavement, who can tolerate not knowing, not curing, not healing and face with us the reality of our powerlessness, that is a friend who cares." (Henri Nouwen)

-------------------------------------------------------
MavenMI6Agent009 is offline   Reply With Quote
Old 04-10-2009, 09:55 PM   #8 (permalink)
 
UltraShy's Avatar
 
Status: Accident of Birth
Join Date: Nov 2003
Location: Milwaukee, WI (Atheist, Libertarian)
Gender: Male
Age: 36
Posts: 25,296



Default

Quote:
Originally Posted by Medline View Post
By the way: Snorting Wellbutrin can easily result in seizures.
Gee, I just take pills by mouth.

I have to use so many nasal sprays for congestion & runny nose that I'm already snorting more than a coke addict.
__________________
Nothing is ever the way it should be
What we deserve we just don't get you see

http://www.insureyourgunrights.com/ (I just became an NRA Life Member.)
UltraShy is offline   Reply With Quote
Reply


Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are Off
Pingbacks are Off
Refbacks are Off



All times are GMT -8. The time now is 05:58 AM.


Powered by vBulletin® Version 3.8.4
Copyright ©2000 - 2010, Jelsoft Enterprises Ltd.
SEO by vBSEO 3.3.0 ©2009, Crawlability, Inc.