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Old 11-28-2009, 05:04 PM   #1 (permalink)
 
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Default Poll:SSRI's effectivness

For those who have taken an SSRI over the years which was the most effective in treating your SAD and/or depression;if any?Please include dosage used.Which ones gave you the least amount of side effects,specifically:weight gain,incresed apettite,sexual dysfunction,lethargy,fatigue?Which gave you the most?
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Old 11-28-2009, 05:46 PM   #2 (permalink)
 
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Try searching the medication forum, I'm sure there are stories of successes, failures, specific regimens, and SSRIs that did and didn't work for people along with side effects. You'll get a lot more info doing that, might take a while, than making a different thread.
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Old 11-28-2009, 06:35 PM   #3 (permalink)
 
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I enjoy taking polls and find them quiet helpful.There are always new people joining this forum and when considering a class of drugs I think people will find it helpful instead of searching everylink for Prozac,Lexapro,Paxil,Zoloft et al. unless they have plenty of patience and time.It gives peoples experiences that others can use as a starting point and direction for further research.
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Old 11-28-2009, 07:27 PM   #4 (permalink)
 
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Try having a look at the reviews in the treatment section here, or at revolutionhealth;

http://www.revolutionhealth.com/drug...ort=sr&stype=c
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Old 11-28-2009, 11:17 PM   #5 (permalink)
 
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SSRIs: They suck. Suck = as effective as a sugar pill, but with side effect.

Paxil sucks.
Prozac sucks.
Lexapro sucks.
Zoloft sucks -- even at a sky-high 300 mg it doesn't help.

Any doctor who suggests I try another SSRI risks a trip to the ER to remove my size 13 foot from his rear end.
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Old 11-28-2009, 11:28 PM   #6 (permalink)
 
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Where's the poll?
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Old 11-29-2009, 09:15 AM   #7 (permalink)
 
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SSRI's has proven their effectiveness in scientific methodes. Anecdotal reports of us are inferior to science.
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Old 11-29-2009, 11:14 AM   #8 (permalink)
 
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Zoloft and lexapro are the only two that have helped with depression not sa. Ive tried 50-100mg of zoloft good for depression. 20mg of Lexapro decent for depression imo.
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Old 11-29-2009, 01:01 PM   #9 (permalink)
 
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Effexor and Pristiq have the fewest side effects due to increase of NA as well as 5-HT
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Old 11-29-2009, 01:10 PM   #10 (permalink)
 
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Quote:
Originally Posted by Forza Italia View Post
SSRI's has proven their effectiveness in scientific methodes. Anecdotal reports of us are inferior to science.
Yes, sir.

I think I speak for everyone on here when I say blanket statements concerning anecdotal evidence, psychiatrists, drug's effectiveness, etc. are just plain dumb.
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Old 11-29-2009, 01:14 PM   #11 (permalink)
 
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Quote:
Originally Posted by db0255 View Post
Yes, sir.

I think I speak for everyone on here when I say blanket statements concerning anecdotal evidence, psychiatrists, drug's effectiveness, etc. are just plain dumb.

This is sooo true... placebo effect is notorious fro bad and good reviews, whereas the true effectiveness is usually mildly positive.

Try Stablon. It has no sexual side effects. well, at least negative ones
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Old 11-29-2009, 01:20 PM   #12 (permalink)
 
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Quote:
Originally Posted by jakeforpresident View Post
Effexor and Pristiq have the fewest side effects due to increase of NA as well as 5-HT
true, because there is an increase of 5-HT, NA, and also dopamine. SNRIs, i dont think i could say they have fewer total* side effects,.....but you are right in saying they have significantly fewer BAD side effects. ....So i find them more tolerable. they still make me feel really weird sometimes, but not as bad as the SSRIs.
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Old 11-29-2009, 01:37 PM   #13 (permalink)
 
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i've tried zoloft, celexa and prozac within SSRIs.
you should expect about 30% drop in your LSAS score after about 3 months of treatment with SSRIs.
1- SSRIs usually work at high doses
2- dont fear about side effects. they diminish rapidly. taper up at begining and taper down when quitting. once my pdoc got me on 60mg of celexa and 80mg of prozac / day

for me this worked better than any other combinations
Zoloft(100mg)+Celexa(20mg)
you may find better results if you add some other meds (benzos ,...)
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Old 11-29-2009, 01:47 PM   #14 (permalink)
 
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Quote:
Originally Posted by Ehsan View Post
i've tried zoloft, celexa and prozac within SSRIs.
you should expect about 30% drop in your LSAS score after about 3 months of treatment with SSRIs.
1- SSRIs usually work at high doses
2- dont fear about side effects. they diminish rapidly. taper up at begining and taper down when quitting. once my pdoc got me on 60mg of celexa and 80mg of prozac / day

for me this worked better than any other combinations
Zoloft(100mg)+Celexa(20mg)
you may find better results if you add some other meds (benzos ,...)

How fast did sexual side effects go away??

Does adding Remeron help sexual side effects, because of its pro-sexual properties??
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Old 11-29-2009, 09:18 PM   #15 (permalink)
 
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Quote:
Originally Posted by jakeforpresident View Post
Does adding Remeron help sexual side effects, because of its pro-sexual properties??
It's more likely that remeron would help decrease sexual side effects due to blocking the 5HT2A and 5HT2C receptors. Although higher doses may incorporate the prosexual effects of blocking alpha-2 adrenergic receptors similarly to yohimbine.
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Old 11-29-2009, 11:34 PM   #16 (permalink)
 
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Quote:
Originally Posted by Forza Italia View Post
SSRI's has proven their effectiveness in scientific methodes.
On the contrary, I believe there were meta-reviews done which showed no real clinical efficacy over a placebo (even though they were "significantly" better).

That's my personal experience with SSRIs too.
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Old 11-30-2009, 02:56 AM   #17 (permalink)
 
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Quote:
Originally Posted by jakeforpresident View Post
How fast did sexual side effects go away??

Does adding Remeron help sexual side effects, because of its pro-sexual properties??
sexual side effects are persistent until quitting them but the amount of dysfunction differs from one to other. I think cyproheptadine works well for reducing sexual side effects

Quote:
Originally Posted by wikipedia
Antagonism of the 5-HT2A and 5-HT2C receptors has beneficial effects on anxiety, sleep and appetite, as well as sexual function regarding the latter.
so remeron and cyproheptadine are both effective in reducing sexual side effects induced by SSRIs and MAOIs.
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Old 11-30-2009, 03:01 AM   #18 (permalink)
 
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Quote:
Originally Posted by John Smith View Post
On the contrary, I believe there were meta-reviews done which showed no real clinical efficacy over a placebo (even though they were "significantly" better).

That's my personal experience with SSRIs too.
i have more than 10 scientific papers which include comparison of SSRIs with placebo in double blinded trials and found SSRIs superior to placebo.
however their average effect is something about 20-30% reduction in LSAS.
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Old 11-30-2009, 04:01 AM   #19 (permalink)
 
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Quote:
Originally Posted by Ehsan View Post
i have more than 10 scientific papers which include comparison of SSRIs with placebo in double blinded trials and found SSRIs superior to placebo.
however their average effect is something about 20-30% reduction in LSAS.
Not saying they don't work, just not well enough to be clinically useful.
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Old 11-30-2009, 04:07 AM   #20 (permalink)
 
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Well Zoloft has done wonders for me. Was the first SSRI I tried and I guess I got lucky because the side effects were minimal and now non-existant and it really helped with my general day to day anxious feelings which enabled me to seek therapy to help with the rest of my recovery.
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