Social Anxiety Support

meyaj · 12-09-2009, 11:46 AM

Just swallowed the first, pill. It's bright orange like the kind you'd find on a Danger! sign, which might be pretty appropriate lol

So, I hate to turn the forums into my journal but I know there's a lot of people interested in the MAOIs. After trying so many other things out, with what a psychiatrist apparently wrote down as "severe refractory depression, severe SAD, and severe GAD", I'm pretty hopeful with this one. Not looking forward to the side effects but people had me scared of the tricyclics too and I tolerated those really well.

I'm constantly fatigued and sleepy and I told my pdoc I was a bit concerned about Nardil making this worse. I'm only at 15mg right now, but she said all I needed to do is give it a week to see how I manage and if I'm not doing well, I'll switch immediately to Parnate. I thought dizziness was a common side effect but she stressed that if I start feeling dizzy, I should stop taking it right away - anybody know why she might say that?

Anyways I've had multiple pdocs tell me that if this doesn't work either, ECT might be in my best interests, which is something I'd rather not do so my fingers are crossed really tightly that the MAOIs will help even a bit. I'm not afraid of the procedure itself, and perhaps it's the social anxiety talking, but I'd rather not live the rest of my life known to my extended family and their friends as the guy who had ECT.

If anybody expresses interest I'll try to keep regular updates about my experiences with this med. Hell, I'll probably still do it even if nobody does

nork123 · 12-09-2009, 11:59 AM

good luck man, I hope it works for you, as I know when it works its like a miracle cure. I look forward to hearing how you get on with it because im very interested in it myself

Vini Vidi Vici · 12-09-2009, 12:29 PM

Quote:

Originally Posted by meyaj

Not looking forward to the side effects but people had me scared of the tricyclics too and I tolerated those really well.

I'm only at 15mg right now, but she said all I needed to do is give it a week to see how I manage and if I'm not doing well, I'll switch immediately to Parnate.

if sexual dysfunction is a problem for you , consider Parnate. not that everyoen cares about sexual dysfunction but it can be a problem for some people lol... I got some bad side effects from Parnate (apathy, no emotion, not caring about anyone /anything) but not everyone gets these. But i got absolutely no Sexual dysfunction...it actually made me, well, kind of *more* yeah interested in such. it was weird.

meyaj · 12-09-2009, 10:12 PM

Okay so for my first update:

The stuff actually surprised me a bit and felt like a stimulant. I was feeling the subjective feeling of a stimulant (peripheral effects and so-called "body load"), was more alert, had the dry mouth that tends to accompany it, and it also seemed to give me an unusual headache. Overall though I was somewhat pleased with it, although I'm only at 1/6th of the max possible dose so far.

My pdoc seemed really concerned about possible extreme hypotension but it feels like my blood pressure has jumped up a bit. I'm just being paranoid, always safe rather than sorry, but what would be the best type of medication to keep on hand to deal with a mild-moderate hypertensive "crisis"? Normally I'd be inclined to think clonidine but being an alpha-2 agonist, it doesn't seem like it'd be ideal in combination with an MAOI. I remember reading about all this stuff before but I'm having a hard time locating the material again - so any pointers in the right direction would be greatly appreciated, and would contribute to my peace of mind.

Quote:

Originally Posted by Vini Vidi Vici

if sexual dysfunction is a problem for you , consider Parnate. not that everyoen cares about sexual dysfunction but it can be a problem for some people lol... I got some bad side effects from Parnate (apathy, no emotion, not caring about anyone /anything) but not everyone gets these. But i got absolutely no Sexual dysfunction...it actually made me, well, kind of *more* yeah interested in such. it was weird.

SA has prevented me from ever even going out on a date, let alone having sex. My libido is stupidly high when I'm not on any medication so it's actually a side effect that felt like a net benefit to me. High sex drive + nobody to help me deal with it = huge frustration.

Maybe if the med works so well that I could actually become sexually involved with someone, I'd consider the side effect a problem. But if it can get me all the way to that point... well that's far better off than what I started with so I wouldn't have much to complete about.

I think it's relatively uncommon but I've heard stories about retrograde ejaculation on MAOIs and I'm more concerned about that than a diminished sex drive.

db0255 · 12-10-2009, 05:38 AM

Quote:

SA has prevented me from ever even going out on a date, let alone having sex. My libido is stupidly high when I'm not on any medication so it's actually a side effect that felt like a net benefit to me. High sex drive + nobody to help me deal with it = huge frustration.

Now we know what meyaj does in his free time.

Guide 4 Dummies · 12-10-2009, 05:52 AM

Quote:

Originally Posted by meyaj

High sex drive + nobody to help me deal with it = huge frustration.

I have, surprise!, the same problem. My libido is insanely high that it's problematic even if I have someone to help me deal with it. I don't want to give more details because it's shocking.

I was hoping that a very high dose of SSRI's could reduce my libido but they had no effect at all. They failed to give me any sexual side effects.

Nowadays, I take an acute dose of Sulpiride (1000 mg) once every 1-2 months. My libido vanishes into thin air within a couple of days thanks to the high level of prolactin. It's like getting a rock off my chest.

I don't suffer from gynecomastia but I'll probably keep taking it even if I did unless I found a female with a similar libido lol

db0255 · 12-10-2009, 06:08 AM

Quote:

Originally Posted by Guide 4 Dummies

I have, surprise!, the same problem. My libido is insanely high that it's problematic even if I have someone to help me deal with it. I don't want to give more details because it's shocking.

I was hoping that a very high dose of SSRI's could reduce my libido but they had no effect at all. They failed to give me any sexual side effects.

Nowadays, I take an acute dose of Sulpiride (1000 mg) once every 1-2 months. My libido vanishes into thin air within a couple of days thanks to the high level of prolactin. It's like getting a rock off my chest.

I don't suffer from gynecomastia but I'll probably keep taking it even if I did unless I found a female with a similar libido lol

And now we know what Guide4Dummies does ALL the time!

But seriously, SSRIs were always anorgasmic for me. Parnate is OK in that regard; it allows me to enjoy sex, but reduces libido.

jim_morrison · 12-10-2009, 06:24 AM

Quote:

Originally Posted by Guide 4 Dummies

I have, surprise!, the same problem. My libido is insanely high that it's problematic even if I have someone to help me deal with it. I don't want to give more details because it's shocking.

I was hoping that a very high dose of SSRI's could reduce my libido but they had no effect at all. They failed to give me any sexual side effects.

Nowadays, I take an acute dose of Sulpiride (1000 mg) once every 1-2 months. My libido vanishes into thin air within a couple of days thanks to the high level of prolactin. It's like getting a rock off my chest.

I don't suffer from gynecomastia but I'll probably keep taking it even if I did unless I found a female with a similar libido lol

Did you try lexapro as one of your SSRI's? that stuff diminished my libido at only 10 mg.

Guide 4 Dummies · 12-10-2009, 06:42 AM

Quote:

Originally Posted by jim_morrison

Did you try lexapro as one of your SSRI's? that stuff diminished my libido at only 10 mg.

It failed to do anything.

@meyaj: I didn't try any MAO-A inhibitors so maybe you will find more luck with them.

meyaj · 12-10-2009, 06:59 PM

Still nothing in the way of side effects, but I hear that the unpleasant stuff tends to kick in at doses closer to 60-90mg.

I keep reading and was even told by my pharmacist that it increases the effects of depressants, especially opiates. But I'm also taking hydromorphone too and it seems to counteract the effects, requiring me to take a double dose.

Quote:

Originally Posted by db0255

Now we know what meyaj does in his free time.

lol hilarious

Actually since I've been starting medication I haven't been really doing it at all. What was once such a compulsion that people didn't even think it was POSSIBLE to do it that often is now something that might happen a few times a month. It's really embarrassing to talk about and my SA is such that I was quite embarrassed just being called out by you (don't worry about it... my problem, not yours

), but I'm actually pretty pleased that it's been diminished to such a large degree.

Although... due to the fact that I just sit at home doing nothing all day, I find myself these days with so much free time and the boredom is killing me.

meyaj · 12-12-2009, 07:57 PM

Well I am constantly sleepy... that I've noticed so far. I'm not just oversleeping, I'm constantly taking naps as well.

But... I notice myself walking around with a stupid grin in my face, feeling like I'm just about to burst out laughing. Reminds me of low-dose LSD. At only 15mg and 4 days in though, I'm not sure whether or not that is a sign of good things to come.

I think I might need to persuade my pdoc to add some modafinil to the mix though...

jakeforpresident · 12-13-2009, 12:55 PM

Quote:

Originally Posted by meyaj

Well I am constantly sleepy... that I've noticed so far. I'm not just oversleeping, I'm constantly taking naps as well.

But... I notice myself walking around with a stupid grin in my face, feeling like I'm just about to burst out laughing. Reminds me of low-dose LSD. At only 15mg and 4 days in though, I'm not sure whether or not that is a sign of good things to come.

I think I might need to persuade my pdoc to add some modafinil to the mix though...

I got waay sleepy on Nardil, and slept 12-16 hours a day. I did feel a little better after a while, but also got apathetic, which I attributed to my deprerssion originally.

John Smith · 12-13-2009, 02:33 PM

Do you have double vision or vertigo with an overwhelming urge to sleep? I had these pretty bad when first starting Nardil.

I also had instant happiness, which has gone now and I virtually hate everyone. Some aspects have improved though, I don't feel apprehensive or anxious in general, I don't feel miserable about myself, and my ADD has improved.

I guess I need to wait for the serotonin to adjust at the 5-ht1a receptor. If it doesn't I might look into pindolol.

12-09-2009, 11:46 AM	#1 (permalink)
meyaj Status: Yes Join Date: Sep 2009 Location: Greater Toronto Area Gender: Male Age: 24 Posts: 1,774	Nardil Just swallowed the first, pill. It's bright orange like the kind you'd find on a Danger! sign, which might be pretty appropriate lol So, I hate to turn the forums into my journal but I know there's a lot of people interested in the MAOIs. After trying so many other things out, with what a psychiatrist apparently wrote down as "severe refractory depression, severe SAD, and severe GAD", I'm pretty hopeful with this one. Not looking forward to the side effects but people had me scared of the tricyclics too and I tolerated those really well. I'm constantly fatigued and sleepy and I told my pdoc I was a bit concerned about Nardil making this worse. I'm only at 15mg right now, but she said all I needed to do is give it a week to see how I manage and if I'm not doing well, I'll switch immediately to Parnate. I thought dizziness was a common side effect but she stressed that if I start feeling dizzy, I should stop taking it right away - anybody know why she might say that? Anyways I've had multiple pdocs tell me that if this doesn't work either, ECT might be in my best interests, which is something I'd rather not do so my fingers are crossed really tightly that the MAOIs will help even a bit. I'm not afraid of the procedure itself, and perhaps it's the social anxiety talking, but I'd rather not live the rest of my life known to my extended family and their friends as the guy who had ECT. If anybody expresses interest I'll try to keep regular updates about my experiences with this med. Hell, I'll probably still do it even if nobody does __________________ Medications I've tried: escitalopram, bupropion, venlafaxine, sertraline, nortriptyline, dextroamphetamine, methylphenidate, phenelzine, tranylcypromine, lorazepam, diazepam, temazepam, clonazepam, zopiclone, gabapentin, hydroxyzine, mirtazapine, trazodone, quetiapine, olanzapine, paliperidone Currently prescribed: 50mg Parnate, 7.5mg Dexedrine twice daily, 40mg Dilaudid (average day), 2mg clonazepam prn, 15mg zopiclone hs

12-12-2009, 07:57 PM	#11 (permalink)
meyaj Status: Yes Join Date: Sep 2009 Location: Greater Toronto Area Gender: Male Age: 24 Posts: 1,774	Well I am constantly sleepy... that I've noticed so far. I'm not just oversleeping, I'm constantly taking naps as well. But... I notice myself walking around with a stupid grin in my face, feeling like I'm just about to burst out laughing. Reminds me of low-dose LSD. At only 15mg and 4 days in though, I'm not sure whether or not that is a sign of good things to come. I think I might need to persuade my pdoc to add some modafinil to the mix though... __________________ Medications I've tried: escitalopram, bupropion, venlafaxine, sertraline, nortriptyline, dextroamphetamine, methylphenidate, phenelzine, tranylcypromine, lorazepam, diazepam, temazepam, clonazepam, zopiclone, gabapentin, hydroxyzine, mirtazapine, trazodone, quetiapine, olanzapine, paliperidone Currently prescribed: 50mg Parnate, 7.5mg Dexedrine twice daily, 40mg Dilaudid (average day), 2mg clonazepam prn, 15mg zopiclone hs

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12-09-2009, 11:59 AM	#2 (permalink)
nork123 Status: SAS Member Join Date: Oct 2009 Location: UK Gender: Male Age: 20 Posts: 395	good luck man, I hope it works for you, as I know when it works its like a miracle cure. I look forward to hearing how you get on with it because im very interested in it myself

12-13-2009, 02:33 PM	#13 (permalink)
John Smith Status: SAS Member Join Date: Jul 2009 Posts: 125	Do you have double vision or vertigo with an overwhelming urge to sleep? I had these pretty bad when first starting Nardil. I also had instant happiness, which has gone now and I virtually hate everyone. Some aspects have improved though, I don't feel apprehensive or anxious in general, I don't feel miserable about myself, and my ADD has improved. I guess I need to wait for the serotonin to adjust at the 5-ht1a receptor. If it doesn't I might look into pindolol.