Hmmm They say getting depressed after a meditation session can be seen as a good achievement. I was 4/5 years on mirt and yes you get depressed on it after a while, in my case even more so than your normal state, drug induced depression. i swithced to lexapro and depression is gone completely and im more social and talkative. The mirt drowsiness is just wrong, feel sleepy even with 9 hours sleep still!! that one is gone now but i got some libido problems on lexapro, its a choice to make what is more imoprtant now, feeling good for now sure is. Mirtazapine does help with meditation greatly i opened my 3rd eye in a couple of months and got in touch with the white bright light, awesome expirience. Now when i quit mirt and on lex i do get lot of pineal gland stimulation, i havent done meditation in a while but when i close my eyes my 3rd eye opens emmidiately, a little strange.