Lithium, Depakote combined? - Social Anxiety Forum
Reply
 
Thread Tools
post #1 of 30 (permalink) Old 02-27-2006, 10:56 AM Thread Starter
SAS Member
 
Join Date: Feb 2006
Location: 25/M/FLA
Posts: 52
Lithium, Depakote combined?

Hey,

My Doc just prescribed me Depakote in addition to my Lithium. That's 600mg of Lithium (relativily low), and 400mg of Depakote per day. I'm not feeling any improvement from the Lithium, but it's also not causing any side effects. They didn't test for my Lithium blood level but they tested for everything else you can possibly test for. So my Doc had to test me again!!!LOL, anyway I needed something to help with the Depression/Anxiety I still deal with. I can't take SSRI's, Buproprin, or the like since they just don't agree with me. I tried to get one of the TCA's but he didn't wanna try any of those so he gave me a script for Depakote. I know these are both mood stabalizers, and aren't generally scripted together. I did find a few cursory trials/research things that used the a combination of the two, but nothing relativily procedure or run of the mill for them.

My question is has anyone else heard of this combination or actually been on it??

By the way if you haven't read my other posts I'm also on Seroquel 125mg a day.


Travis

"IT can BE what YOU want IT to BE......."

RX: Lithium 600mg, Effexor 150mg, Provigil 200mg, Seroquel 125mg
EgoLost is offline  
Sponsored Links
Advertisement
 
post #2 of 30 (permalink) Old 02-27-2006, 11:40 AM
up an down, here we go!!
 
firedancer's Avatar
 
Join Date: Nov 2003
Location: North Carolina
Gender: Female
Posts: 356
I have not heard of that particular combo, but anything is possible.

My pdoc just put me on Depakote too (250mg) and I am also on Lamictal (now 100mg). From my understanding, in my case, the Lamictal is for the BP depression end of the spectrum and the Depakote is for the hypomania. I am also taking Lyrica for my migraines (not working) but it has helped my anxiety.

I go back to my pdoc next week. And will have to have my blood checked then.

Let us know how you are doing. I'm curious about your combo.

_jen

Dx: BiPolar, Intractable Migraines, Social & General Anxiety, Idiopathic Seizures 7/07

Current Rx: Seroquel, Lamictal, Zanaflex

Rx: I have been on just about everything once. Anti-Depressants, Anti-Convulsants, Anti-Psychotics, Benzos, etc.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.

firedancer is offline  
post #3 of 30 (permalink) Old 02-27-2006, 11:47 AM Thread Starter
SAS Member
 
Join Date: Feb 2006
Location: 25/M/FLA
Posts: 52
cool

I missread the prescription, it's actually 250mg twice a day, instead of 200mg, sorry. Like I said there have been a few cursory studies done on the combination. Also I haven't found any interactions between them that could be potentially toxic, only complications relative to the illness they are used to treat. Nothing new about that though.

I'll let you guys know how it works.

P.S. I have saw some studies related to the combination of Lamitcal and Depakote, or Lamictal and Lithium. So there may be some promise there for you!

Travis

"IT can BE what YOU want IT to BE......."

RX: Lithium 600mg, Effexor 150mg, Provigil 200mg, Seroquel 125mg
EgoLost is offline  
post #4 of 30 (permalink) Old 02-27-2006, 12:01 PM
up an down, here we go!!
 
firedancer's Avatar
 
Join Date: Nov 2003
Location: North Carolina
Gender: Female
Posts: 356
I hope this combo works.

Have you checked out http://www.crazymeds.org ? There is ton of info there and they have a message board too. Also http://www.crazyboards.org (used to be the same thing and they split).

Dx: BiPolar, Intractable Migraines, Social & General Anxiety, Idiopathic Seizures 7/07

Current Rx: Seroquel, Lamictal, Zanaflex

Rx: I have been on just about everything once. Anti-Depressants, Anti-Convulsants, Anti-Psychotics, Benzos, etc.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.

firedancer is offline  
post #5 of 30 (permalink) Old 02-27-2006, 12:21 PM Thread Starter
SAS Member
 
Join Date: Feb 2006
Location: 25/M/FLA
Posts: 52
Thanks firedancer,

I wasn't aware there was a "New" Crazymeds forum. I frequent the old one and The actual Crazymeds Info pages.

I noticed someone replyed to one of your posts saying not to take Aspirin or Alkaseltzer(sp). This is very true, my Doc told me this and my prescribing info also noted it. Just a reminder.

For anyonoe else who is wondering, I did see someone mention on that same crazyforum post taking Depakote and Lithium together. It's not all "THAT" uncommon I think. Just not heard of much.

Travis

"IT can BE what YOU want IT to BE......."

RX: Lithium 600mg, Effexor 150mg, Provigil 200mg, Seroquel 125mg
EgoLost is offline  
post #6 of 30 (permalink) Old 02-27-2006, 02:56 PM
up an down, here we go!!
 
firedancer's Avatar
 
Join Date: Nov 2003
Location: North Carolina
Gender: Female
Posts: 356
i read the PI sheet so i knew about the aspirin. i'm taking vicoprofen for my migraine pain, so i'm covered there too.

Dx: BiPolar, Intractable Migraines, Social & General Anxiety, Idiopathic Seizures 7/07

Current Rx: Seroquel, Lamictal, Zanaflex

Rx: I have been on just about everything once. Anti-Depressants, Anti-Convulsants, Anti-Psychotics, Benzos, etc.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.

firedancer is offline  
post #7 of 30 (permalink) Old 02-27-2006, 05:56 PM
I can do this!
 
Caedmon's Avatar
 
Join Date: Dec 2003
Location: Cascadia
Gender: Male
Age: 33
Posts: 4,037
Why the Depakote? Have you been cycling/manic?

Depakote + Lithium is a very common combo, especially if you want something that works fast. Also along with Seroquel - sounds okay to me. They did test your Lithium blood level initially, right?

Medication-related posts are for brainstorming purposes only. Talk to your doctor.
Meds: Parnate, Adderall, Lamictal, Rozerem (May 2015)
Caedmon is offline  
post #8 of 30 (permalink) Old 02-27-2006, 07:02 PM Thread Starter
SAS Member
 
Join Date: Feb 2006
Location: 25/M/FLA
Posts: 52
I asked for something other than an SSRI for some persisting depression and anxiety. I think he's trying to hold me over till the Lithium and Seroquel kick in. As far as the Lithium blood testing; I supposedly had the test last month, but they tested everything BUT my Lithium level. Doctors mistake, so I had it done today. I'm still on only 300mg twice a day. I have no side effects or benefits from the lithium, so I figure I'm not at the theraputic dose yet, but I'll stay at the same dose till the test comes back.

I honestly wasn't aware this Lithium/Depakote combo was that commonplace. I've found very little research, etc on it. You don't have any links you could steer me toward do you Caedmon?

Also I see that I need to be blood tested for the Depakote too.

Travis

"IT can BE what YOU want IT to BE......."

RX: Lithium 600mg, Effexor 150mg, Provigil 200mg, Seroquel 125mg
EgoLost is offline  
post #9 of 30 (permalink) Old 02-27-2006, 08:33 PM
I can do this!
 
Caedmon's Avatar
 
Join Date: Dec 2003
Location: Cascadia
Gender: Male
Age: 33
Posts: 4,037
Quote:
Originally Posted by EgoLost
I asked for something other than an SSRI for some persisting depression and anxiety. I think he's trying to hold me over till the Lithium and Seroquel kick in. As far as the Lithium blood testing; I supposedly had the test last month, but they tested everything BUT my Lithium level. Doctors mistake, so I had it done today. I'm still on only 300mg twice a day. I have no side effects or benefits from the lithium, so I figure I'm not at the theraputic dose yet, but I'll stay at the same dose till the test comes back.
Argh! For all we know, Lithium could be effective monotherapy if it were only at an effective blood level! Well I assume you'll figure all this out when the labs come back.

Not sure that this combination is common, but I wouldn't think it uncommon. Lithium for depression and Depakote for mania or something like that. Is all I was thinking. Depakote does make sense for anxiety, although not really for depression.

Read everything on Dr. Phelps' page. Or straight to treatment. Read every link! I love this page.

Medication-related posts are for brainstorming purposes only. Talk to your doctor.
Meds: Parnate, Adderall, Lamictal, Rozerem (May 2015)
Caedmon is offline  
post #10 of 30 (permalink) Old 02-27-2006, 09:01 PM
up an down, here we go!!
 
firedancer's Avatar
 
Join Date: Nov 2003
Location: North Carolina
Gender: Female
Posts: 356
That is a great link. I have spent alot of time on that site.

_jen

Dx: BiPolar, Intractable Migraines, Social & General Anxiety, Idiopathic Seizures 7/07

Current Rx: Seroquel, Lamictal, Zanaflex

Rx: I have been on just about everything once. Anti-Depressants, Anti-Convulsants, Anti-Psychotics, Benzos, etc.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.

firedancer is offline  
post #11 of 30 (permalink) Old 02-28-2006, 06:59 AM
I can do this!
 
Caedmon's Avatar
 
Join Date: Dec 2003
Location: Cascadia
Gender: Male
Age: 33
Posts: 4,037
Have you taken the Depakote yet Travis? How is it affecting you? How about you Jen?

Medication-related posts are for brainstorming purposes only. Talk to your doctor.
Meds: Parnate, Adderall, Lamictal, Rozerem (May 2015)
Caedmon is offline  
post #12 of 30 (permalink) Old 02-28-2006, 12:26 PM
up an down, here we go!!
 
firedancer's Avatar
 
Join Date: Nov 2003
Location: North Carolina
Gender: Female
Posts: 356
or me, doc told me i could stop the seroquel. so i was hoping that it help with my insomnia (from mania) that i have had the past 2.5 weeks. nope. i'm still staying up all night. this is something that i will have to address next week at my next appt.

other than that, just some stomach discomfort.

Dx: BiPolar, Intractable Migraines, Social & General Anxiety, Idiopathic Seizures 7/07

Current Rx: Seroquel, Lamictal, Zanaflex

Rx: I have been on just about everything once. Anti-Depressants, Anti-Convulsants, Anti-Psychotics, Benzos, etc.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.

firedancer is offline  
post #13 of 30 (permalink) Old 02-28-2006, 06:35 PM Thread Starter
SAS Member
 
Join Date: Feb 2006
Location: 25/M/FLA
Posts: 52
I started this morning. Depakote reminded me of Lithium in a way when I started using it. Slightly blurred vision, (not all the time, transient), dry taste, but unbelievably no stomach discomfort. It has made me tired, in a way. Not so much zonked out, but "i could take a nap," tired. As long as I'm busy I don't notice it much.

I think it's actually cooled the anxiety off a bit today, that's a good thing. But it has seemed to elavate the depression. This may be because of the fatigue it is causing. I just can't seem to kick this down in the dumps feeling, that I have for no reason.

Tommmorows another day, but looking optimistic!!!

Travis

"IT can BE what YOU want IT to BE......."

RX: Lithium 600mg, Effexor 150mg, Provigil 200mg, Seroquel 125mg
EgoLost is offline  
post #14 of 30 (permalink) Old 02-28-2006, 06:44 PM
up an down, here we go!!
 
firedancer's Avatar
 
Join Date: Nov 2003
Location: North Carolina
Gender: Female
Posts: 356
you are taking it the morning? my pdoc told me to take it at night.

Dx: BiPolar, Intractable Migraines, Social & General Anxiety, Idiopathic Seizures 7/07

Current Rx: Seroquel, Lamictal, Zanaflex

Rx: I have been on just about everything once. Anti-Depressants, Anti-Convulsants, Anti-Psychotics, Benzos, etc.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.

firedancer is offline  
post #15 of 30 (permalink) Old 03-01-2006, 06:50 PM Thread Starter
SAS Member
 
Join Date: Feb 2006
Location: 25/M/FLA
Posts: 52
Taking it twice a day at Breakfast and Dinner. Today was better, I wasn't as tired actually. It's not so bad really. I think it's helping a little. But not as much as Lithium did when I first started it.

Travis

"IT can BE what YOU want IT to BE......."

RX: Lithium 600mg, Effexor 150mg, Provigil 200mg, Seroquel 125mg
EgoLost is offline  
post #16 of 30 (permalink) Old 03-01-2006, 08:48 PM
up an down, here we go!!
 
firedancer's Avatar
 
Join Date: Nov 2003
Location: North Carolina
Gender: Female
Posts: 356
i think that i am going to have to call my pdoc. i've been on it a week and have not sleep a single night. i usually make myself go to bed around 7am and i sleep for about 4 hours and them i'm up again. i've been told that this is not typical.

i don't know, but he will probably tell me to up the dosage.

_jen

Dx: BiPolar, Intractable Migraines, Social & General Anxiety, Idiopathic Seizures 7/07

Current Rx: Seroquel, Lamictal, Zanaflex

Rx: I have been on just about everything once. Anti-Depressants, Anti-Convulsants, Anti-Psychotics, Benzos, etc.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.

firedancer is offline  
post #17 of 30 (permalink) Old 03-01-2006, 10:01 PM
I can do this!
 
Caedmon's Avatar
 
Join Date: Dec 2003
Location: Cascadia
Gender: Male
Age: 33
Posts: 4,037
Are you still taking the same Seroquel along with the new Depakote Jen?

I'm having trouble sleeping too, I don't know if it's hypomania or what. Functioning on 2 hours despite not being tired is... surprisingly crappy. I took some Risperdal (2 mg) and that is helping a bit.

Medication-related posts are for brainstorming purposes only. Talk to your doctor.
Meds: Parnate, Adderall, Lamictal, Rozerem (May 2015)
Caedmon is offline  
post #18 of 30 (permalink) Old 03-02-2006, 01:13 AM
up an down, here we go!!
 
firedancer's Avatar
 
Join Date: Nov 2003
Location: North Carolina
Gender: Female
Posts: 356
Pdoc told me to stop the Seroquel, but I taken it since I started Depa but didn't notice any tiredness. Funny because before the hypo, I could take 75mg a night and sleep like a baby. Before Depa, it got to the point where it didn't work when I was hypomanic and I've been like this for almost 4 weeks now. I'm up all night and it sucks. I'm not tired at all.

I'm going to call him tomorrow. Hopefully he can recommend something.

Dx: BiPolar, Intractable Migraines, Social & General Anxiety, Idiopathic Seizures 7/07

Current Rx: Seroquel, Lamictal, Zanaflex

Rx: I have been on just about everything once. Anti-Depressants, Anti-Convulsants, Anti-Psychotics, Benzos, etc.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.

firedancer is offline  
post #19 of 30 (permalink) Old 03-02-2006, 05:38 AM Thread Starter
SAS Member
 
Join Date: Feb 2006
Location: 25/M/FLA
Posts: 52
Seroquel only makes me sleep if I'm already tired and exausted. In that state I'm out like a light. But if I'm well rested it won't do a thing. That's at 100-125mg.

Along with Depakote the last few days it's cuased enough fatigue to do the trick at 100mg. That's a good thing I guess, but who wants to get that tired everyday to sleep? Ya know even deep, hard sleep feels taxing on the body, in a tiring sense!

But I'm able to sleep for at least 6 hours. I can not really complain on the sleep side.

Firedancer,

You haven't slept since you started the depakote? I'd reconsider its benefits before I dropped the old scripts, i.e. Seroquel.

Travis

"IT can BE what YOU want IT to BE......."

RX: Lithium 600mg, Effexor 150mg, Provigil 200mg, Seroquel 125mg
EgoLost is offline  
post #20 of 30 (permalink) Old 03-02-2006, 10:44 AM
up an down, here we go!!
 
firedancer's Avatar
 
Join Date: Nov 2003
Location: North Carolina
Gender: Female
Posts: 356
I called my pdoc today and he's out of the office until Mon, which is when my appt is.

I'm really considering taking the Seroquel anyway. If I have to take more than the usual 75mg, then I will.

The problem is that I am wired at night. And when I wake up from the 3-4 hours of sleep, I'm wired again (unless I have a migraine, which I still am).

Oh, sorry for the thread hijack.

Dx: BiPolar, Intractable Migraines, Social & General Anxiety, Idiopathic Seizures 7/07

Current Rx: Seroquel, Lamictal, Zanaflex

Rx: I have been on just about everything once. Anti-Depressants, Anti-Convulsants, Anti-Psychotics, Benzos, etc.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.


To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.

firedancer is offline  
Reply

Thread Tools
Show Printable Version Show Printable Version
Email this Page Email this Page



Similar Threads
Thread Thread Starter Forum Replies Last Post
Depakote and GABA transaminase inhibition korey Medication 2 03-15-2009 08:09 AM
Whats the difference between Depakote and Depakene? Noca Medication 2 03-11-2008 11:10 PM
cymbalta depakote, buspar paranoia Medication 7 12-20-2006 11:46 AM
depakote allalone9863 Medication 5 07-28-2006 01:21 PM
Depakote/ Depakene/ Depacon Caedmon Medication 4 05-23-2006 12:56 PM

Posting Rules  
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are Off
Pingbacks are Off
Refbacks are Off

 
For the best viewing experience please update your browser to Google Chrome