Klonopin: Halflife v. Noticable Duration - Social Anxiety Forum
X

Download the SAS Android App

Or switch to mobile version of the forums

X

Download the SAS iPhone App

Or switch to mobile version of the forums

Help/FAQLog InJoin SAS
Go Back   Social Anxiety Forum > Recovery > Medication

Like Tree1 Liked Posts
  • 1 Post By Foh_Teej

Reply
Old 04-11-2007, 09:03 PM   #1 (permalink)
 
Status: SAS Member
Join Date: Jul 2006
Location: Cincinnati, OH
Age: 28
Posts: 357



Default Klonopin: Halflife v. Noticable Duration

Klonopin has a half life of 30-40 hours (says wikipedia, but I think that's at least ballpark right, if not exact). Now, I pop a pill and I get a noticeable effect that lasts between 3-6 hours. Even when I pop a high dosage, the duration is about this long. How can the drug have such a long half life and such a short window of noticeable effect?

Klonopin also seems to have a less noticeable, more subliminal calming effect, but even this seems to last about 12 hours at most.
jakejohnson007 is offline   Reply With Quote
Old 04-12-2007, 05:18 AM   #2 (permalink)
 
Status: Permanently Banned
Join Date: Jul 2005
Location: melbourne australia
Posts: 1,379



Default re: Klonopin: Halflife v. Noticable Duration

these half life figures make no sense to me, K helps me for about 4 hours max
arthur56 is offline   Reply With Quote
Old 04-12-2007, 12:36 PM   #3 (permalink)
 
Noca's Avatar
 
Status: Spectacular Member
Join Date: Jun 2005
Location: Ontario
Gender: Male
Age: 28
Posts: 18,516



Default

Klonopin does 5-6 hours for me.
__________________
“There is a cult of ignorance in the United States, and there has always been. The strain of anti-intellectualism has been a constant thread winding its way through our political and cultural life, nurtured by the false notion that democracy means that "my ignorance is just as good as your knowledge."”
--Isaac Asimov

Quitting while you are ahead isn't the same thing as quitting; lesser known fact
Noca is offline   Reply With Quote
Old 04-12-2007, 07:30 PM   #4 (permalink)
 
Status: SAS Member
Join Date: Jun 2006
Location: New Jersey
Age: 25
Posts: 2,409



Default re: Klonopin: Halflife v. Noticable Duration

the half life of a drug is not how long the effects last but basically how long it takes half of the drug to leave your system. klonopin has a mean half life of 35 hours and it's effects last me about 6-7 hours.
__________________
"I hate to advocate drugs, alcohol, violence, or insanity to anyone, but they've always worked for me." -Hunter S. Thompson
Speak Easy is offline   Reply With Quote
Old 04-12-2007, 07:34 PM   #5 (permalink)
 
Status: SAS Member
Join Date: Jan 2007
Posts: 249



Default re: Klonopin: Halflife v. Noticable Duration

as far as i understand it "halflife" just refers to the time it takes for one half of the original dose of a medication to leave your body. it has nothing to do with how much or for how long you feel the effect of the drug.

but i could be wrong
__________________
dx: bipolar ii, panic disorder, PMDD, SA
rx: mirtazapine 30mg, lamotrigine 200mg, levonorgestrel 150µg, clonazepam prn, propranolol prn.
Jean is offline   Reply With Quote
Old 04-12-2007, 07:37 PM   #6 (permalink)
 
Status: SAS Member
Join Date: Jan 2007
Posts: 249



Default re: Klonopin: Halflife v. Noticable Duration

oops! LDG you beat me to it!
__________________
dx: bipolar ii, panic disorder, PMDD, SA
rx: mirtazapine 30mg, lamotrigine 200mg, levonorgestrel 150µg, clonazepam prn, propranolol prn.
Jean is offline   Reply With Quote
Old 04-12-2007, 08:59 PM   #7 (permalink)
 
Status: SAS Member
Join Date: Jul 2006
Location: Cincinnati, OH
Age: 28
Posts: 357



Default

how long does Xanax XR last? Or is there any other benzo with a longer window of action than Klonopin?

I wish there was a benzo 'patch' or something that kept you on a steady dose of it at all times, controlled release.
jakejohnson007 is offline   Reply With Quote
Old 04-12-2007, 10:11 PM   #8 (permalink)
 
Noca's Avatar
 
Status: Spectacular Member
Join Date: Jun 2005
Location: Ontario
Gender: Male
Age: 28
Posts: 18,516



Default

a drug's half-life is relative to how long it lasts
__________________
“There is a cult of ignorance in the United States, and there has always been. The strain of anti-intellectualism has been a constant thread winding its way through our political and cultural life, nurtured by the false notion that democracy means that "my ignorance is just as good as your knowledge."”
--Isaac Asimov

Quitting while you are ahead isn't the same thing as quitting; lesser known fact
Noca is offline   Reply With Quote
Old 04-13-2007, 01:02 PM   #9 (permalink)
 
Status: SAS Member
Join Date: Jan 2007
Posts: 249



Default

Quote:
Originally Posted by jakejohnson007
I wish there was a benzo 'patch' or something that kept you on a steady dose of it at all times, controlled release.
this sounds like a money maker, so why not? i'd be curious to try it...
__________________
dx: bipolar ii, panic disorder, PMDD, SA
rx: mirtazapine 30mg, lamotrigine 200mg, levonorgestrel 150µg, clonazepam prn, propranolol prn.
Jean is offline   Reply With Quote
Old 04-13-2007, 03:27 PM   #10 (permalink)
 
Noca's Avatar
 
Status: Spectacular Member
Join Date: Jun 2005
Location: Ontario
Gender: Male
Age: 28
Posts: 18,516



Default

Quote:
Originally Posted by Jean
Quote:
Originally Posted by jakejohnson007
I wish there was a benzo 'patch' or something that kept you on a steady dose of it at all times, controlled release.
this sounds like a money maker, so why not? i'd be curious to try it...
I wish all my drugs were patches like my fentanyl 72 hour release patch.
__________________
“There is a cult of ignorance in the United States, and there has always been. The strain of anti-intellectualism has been a constant thread winding its way through our political and cultural life, nurtured by the false notion that democracy means that "my ignorance is just as good as your knowledge."”
--Isaac Asimov

Quitting while you are ahead isn't the same thing as quitting; lesser known fact
Noca is offline   Reply With Quote
Old 04-13-2007, 04:23 PM   #11 (permalink)
 
ThirdEyeGrind's Avatar
 
Status: ThirdEyeGrind
Join Date: Feb 2006
Location: United States
Gender: Male
Age: 28
Posts: 1,284



Default re: Klonopin: Halflife v. Noticable Duration

**** when I take my Klonopin which is 3mg at once, the effects only last for about 2 to 3 hours max. Then its all up to me to try and be my normal self. People even say to me stuff like "i bet you way different at home" and "i'm away from my comfort zone". I pretty much tell them thats pretty much what it is.
ThirdEyeGrind is offline   Reply With Quote
Old 04-14-2007, 02:30 PM   #12 (permalink)
 
Status: Permanently Banned
Join Date: Dec 2006
Posts: 288



Default re: Klonopin: Halflife v. Noticable Duration

I dont notice any effects at all at the 1mg level but if I take like 3mg at once I will feel calm and anxiety free for about 3-4 hours as well. Im assuming that Klonopin only has subtle effects on the brain for the other 36 hours of halflife time that are unaccounted for.
scotthallkevinnash is offline   Reply With Quote
Old 04-14-2007, 03:12 PM   #13 (permalink)
 
UltraShy's Avatar
 
Status: Surrounded by Sadness
Join Date: Nov 2003
Location: Milwaukee, WI (BDSM sadist, Libertarian)
Gender: Male
Age: 41
Posts: 31,265



Default re: Klonopin: Halflife v. Noticable Duration

I wish Scrotacles (the pharmacy student) was around here. This is the perfect question for him.

I remember him once explaining that eventhough Valium (I'm going with an example he used) has the longest half-life of any benzo it actually leaves the brain quite rapidly compared to what you might expect simply based on half life. The half-life of Valium (and active metabolites) is up to 200 hours. As a former Valium user, I can assure you Valium most certainly doesn't last a week nor even close -- it doesn't even last a day.

Since I'm just a pill popper, I can't explain why half-life and actual duration of effect are often so vastly different.
__________________
I wonder what reason I have to live
Desperately I have searched for a meaning
Is it now time for me to let go of the world
UltraShy is offline   Reply With Quote
Old 04-16-2007, 12:52 AM   #14 (permalink)
 
Status: SAS Member
Join Date: Oct 2006
Posts: 11



Default re: Klonopin: Halflife v. Noticable Duration

Wow. When I take .25mg of Klonopin before bed it lasts right into the next day for me. The last time I took it I was a lost zombie the next day at work and couldn't figure out why... my fiance reminded me... by the next day I was ok.

I guess I'm just a sensitive girl.
photogirl is offline   Reply With Quote
Old 04-16-2007, 01:03 PM   #15 (permalink)
 
korey's Avatar
 
Status: SAS Member
Join Date: Apr 2006
Location: Mississippi, USA
Gender: Male
Age: 26
Posts: 1,936



Default

I think half-life is just a way to keep track of a medication's dosing schedule. Back when I was taking zithromax (one of the various antibiotics I tried for acne), I only took it every other day because of its very long half-life.

I think the amount of time it takes for a medication to go through "first pass metabolism" (without any active metabolites, assuming), with respect to its known bioavailability, is the amount of time that a medication is at its most noticably effective level in the body. Taking those factors into consideration makes half-life useless unless you're trying to figure out a proper dosing schedule.

I think, at least
__________________
Rx:
Wellbutrin SR 300mg, Eskalith CR 900mg, Luvox 100mg

Things I have tried:
Lexapro, Zoloft, Celexa, Prozac, Paxil, Effexor XR, Remeron, Wellbutrin SR, Eskalith CR, Topamax, Valium, Xanax, Ativan, Ambien, Restoril, Desyrel, Ritalin, Adderall, Dexedrine, Inderal, Lopressor, Thorazine, Lamictal, Abilify, Depakote, Geodon, Seroquel, doxepin, chloral hydrate
korey is offline   Reply With Quote
Old 08-12-2012, 11:29 AM   #16 (permalink)
 
Status: SAS Member
Join Date: Aug 2012
Posts: 1



Default drugs never leave your body.....ever

half life refers to the amount of time it takes for half the drug to be eliminated by your body........if you cut something in half it never ever reaches 0......it can get close(ie .000000000000000001 etc) but never fully leaves your body. this doesn't mean your withdrawl symptoms won't go away.....but it is just something to think about before ingesting anything......the saying you are what you eat........well to a certain extent is 100% fact.....nothing you consume ever really leaves you =)
ipayattention is offline   Reply With Quote
Old 08-12-2012, 12:06 PM   #17 (permalink)
 
Foh_Teej's Avatar
 
Status: Occasionally Bannned
Join Date: May 2004
Location: DFW
Gender: Male
Age: 34
Posts: 1,402



Default

Did you really just resurrect a 5 year old post to pretty much say what was already said?
basuraeuropea likes this.
__________________
I encourage everyone to read the bible. It is the best way to atheism if you leave your heart to pumping blood and your brain to critical thinking.
Foh_Teej is offline   Reply With Quote
Old 08-12-2012, 03:28 PM   #18 (permalink)
 
Status: Permanently Banned
Join Date: Apr 2012
Location: Oregon, USA
Gender: Male
Posts: 4,394



Default

Quote:
Originally Posted by ipayattention View Post
the saying you are what you eat........well to a certain extent is 100% fact.....nothing you consume ever really leaves you =)

If you are what you eat, I could be you tomorrow.
istayhome is offline   Reply With Quote
Reply

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are Off
Pingbacks are Off
Refbacks are Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
Why is it so noticable that I turn red :( spoox Frustration 19 05-25-2013 09:56 PM
Klonopin - How Long To Kick In & Duration? StampedeTheVash Medication 43 01-08-2013 10:03 PM
Duration at location UltraShy General Discussion 42 07-30-2009 10:28 AM
Duration of SSRI Side Effects Teo Medication 4 07-17-2007 05:58 AM
Halflife 2 : Episode 2 loner2389 Geek Central 3 03-01-2007 09:54 PM

All times are GMT -7. The time now is 04:23 AM.
Powered by vBulletin® ©2000-2014, vBulletin Solutions, Inc.
SEO by vBSEO 3.6.0 ©2011, Crawlability, Inc. User Alert System provided by Advanced User Tagging v3.1.0 (Pro) - vBulletin Mods & Addons Copyright © 2014 DragonByte Technologies Ltd.