Social Anxiety Support

BearFan · 11-02-2009, 05:09 PM

I was wondering what the conversion rate of Effexor XR users to Pristiq were? I found effectiveness with Effexor in reducing social anxiety symptoms, however the sexual side effects were truly debilitating. I did try the Pristiq Sample pack for 2 weeks and it felt like effexor but without the same 'calmness' feeling I felt on Effexor. I know this was not a full trial. I've heard some reports that the sexual side effects were void on Pristiq, is this true for many users or just "wishful thinking"

Thanks

jim_morrison · 11-02-2009, 06:07 PM

My textbook claims that roughly 50% of venlafaxine (effexor) is converted into desvenlafaxine (pristiq) if that helps.

Pristiq has a very similair 5HT(serotonin):NE ratio to cymbalta though, so my guess would be that sexual side effects with pristiq and cymbalta would be pretty comparable.
As for the sexual dysfunction with effexor, it has a wider 5HT:NE ratio than the others so at lower doses it primarily effects serotonin and hence has more sexual sid effects, although some users seem to report that taking above 200 mg of effexor diminishes the sexual side effects, as the strong noradrenaline effects start to kick in at that point.

BearFan · 11-04-2009, 11:48 AM

Someone said that Pristiq it is currently awaiting trials to be approved for anixety and social phobia. Is this true? I felt quite a bit more 'on edge' on the short time I was on Pristiq than when on Effexor.

MavenMI6Agent009 · 11-04-2009, 11:53 AM

I was hoping Prestiq would help me but not really. I didnt get anything out of it.

11-02-2009, 05:09 PM	#1 (permalink)
BearFan Status: SAS Member Join Date: Mar 2008 Posts: 26	Is Pristiq an Effective med for social anxiety and is it truely void of effexor sides I was wondering what the conversion rate of Effexor XR users to Pristiq were? I found effectiveness with Effexor in reducing social anxiety symptoms, however the sexual side effects were truly debilitating. I did try the Pristiq Sample pack for 2 weeks and it felt like effexor but without the same 'calmness' feeling I felt on Effexor. I know this was not a full trial. I've heard some reports that the sexual side effects were void on Pristiq, is this true for many users or just "wishful thinking" Thanks

11-02-2009, 06:07 PM	#2 (permalink)
jim_morrison Status: SAS Member Join Date: Aug 2008 Location: Australia Gender: Male Age: 23 Posts: 1,027	My textbook claims that roughly 50% of venlafaxine (effexor) is converted into desvenlafaxine (pristiq) if that helps. Pristiq has a very similair 5HT(serotonin):NE ratio to cymbalta though, so my guess would be that sexual side effects with pristiq and cymbalta would be pretty comparable. As for the sexual dysfunction with effexor, it has a wider 5HT:NE ratio than the others so at lower doses it primarily effects serotonin and hence has more sexual sid effects, although some users seem to report that taking above 200 mg of effexor diminishes the sexual side effects, as the strong noradrenaline effects start to kick in at that point. __________________ Warning: I am not a trained medical professional. Any information provided by me is based on my own personal experiences and research and is not intended to be used as professional medical advice. Please contact a medical professional before taking any action that may be discussed on this board.

11-04-2009, 11:53 AM	#4 (permalink)
MavenMI6Agent009 Status: Cook Join Date: Aug 2004 Location: EL Crapo, Tx Gender: Male Posts: 13,647	I was hoping Prestiq would help me but not really. I didnt get anything out of it. __________________ "The friend who can be silent with us in a moment of despair or confusion, who can stay with us in an hour of grief and bereavement, who can tolerate not knowing, not curing, not healing and face with us the reality of our powerlessness, that is a friend who cares." (Henri Nouwen) -------------------------------------------------------

11-04-2009, 11:48 AM	#3 (permalink)
BearFan Status: SAS Member Join Date: Mar 2008 Posts: 26	Someone said that Pristiq it is currently awaiting trials to be approved for anixety and social phobia. Is this true? I felt quite a bit more 'on edge' on the short time I was on Pristiq than when on Effexor.