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Old 10-29-2009, 10:51 PM   #1 (permalink)
 
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Default Glutamine medication

Hi All

I recently has a session with my psychiatrist, and whilst I'm coping to a degree with the SA on my present dose of Paroxetine and Zyprexa, I asked about new treatments and research. Apparently there is some development in the area of regulating glutamine (I hope I've got this right). He indicated that if it proves successful, commercial availability would be about 3-5 years from now.

Someone may know something more on this?? Like I said, I hope I've identified the "glutamine" correctly.

Cheers

Adam
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Old 10-29-2009, 11:50 PM   #2 (permalink)
 
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He wasn't referring to Pagoclone was he?

http://en.wikipedia.org/wiki/Pagoclone
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Old 10-30-2009, 01:32 AM   #3 (permalink)
 
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Quote:
Originally Posted by jim_morrison View Post
He wasn't referring to Pagoclone was he?

http://en.wikipedia.org/wiki/Pagoclone
That just sounds like a targeted GABA agonist, unless I'm missing something. Which is entirely possible, I'm kind of scatterbrained and jump between paragraphs without reasons. Although Pagoclone sounds interesting... wondering if I'd get the same hallucinations that zopiclone gives me.

I think he means to say glutamate though rather than glutamine. There are a lot of glutamatergic drugs though so it's difficult to tell which one he could possibly mean without more info.
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Medications I've tried: escitalopram, bupropion, venlafaxine, sertraline, nortriptyline, hydroxyzine, lorazepam, diazepam, temazepam, clonazepam, zopiclone, mirtazapine, trazodone, quetiapine, olanzapine, paliperidone

Currently taking: 2mg nortriptyline hs(tapering), 7.5mg-15mg zopiclone hs, 2mg clonazepam prn
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Old 11-02-2009, 10:03 PM   #4 (permalink)
 
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Yeah, I wonder if you could take zopiclone by night, and pagoclone by day, for more targeted anxiety/insomnia relief.

I definitly think that GABA-A selective α2/α3 agonists are the way forward for future anxiolytics though, rather than stuff like buspar.
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Old 11-02-2009, 10:27 PM   #5 (permalink)
 
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Are we talking L-Glutamine ? I take it every day . 10G's
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Old 11-02-2009, 10:32 PM   #6 (permalink)
 
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Nah, I think he was talking about some form of medication which regulates either glutamine or glutamate, not sure which drug it is though.
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