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Old 04-20-2006, 07:23 PM   #1 (permalink)
 
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Default Effexor vs. Paxil

Hi! I was searching through the old messages trying to find something that might answer my questions, but I didn't, so here goes:

Has anyone taken both Paxil and Effexor and if so which was better and why?

My dr. is taking my off Paxil because it has pretty much done nothing for me at all, even at 40 mgs, and he wants to start me on effexor.

Any advice you can give?

Thanks!
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Old 04-21-2006, 08:02 AM   #2 (permalink)
 
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Well I'm thinking of making the switch from an SSRI similar to Paxil (Lexapro) to a drug similar to Effexor (Cymbalta). I'll let you know how that goes, if I end up doing it. So far, only Paxil CR (25 mgs) has been the only thing that's worked for me.

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Old 04-21-2006, 09:04 AM   #3 (permalink)
 
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Thanks maggi-

Let's keep each other updated on how the switch works.

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Old 04-21-2006, 01:12 PM   #4 (permalink)
 
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Default Re: Effexor vs. Paxil

Quote:
Originally Posted by christiem
Has anyone taken both Paxil and Effexor and if so which was better and why?
I have, and I'll call it a tie. They were both equally useless.
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Old 04-21-2006, 01:32 PM   #5 (permalink)
 
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Its different for each person. If effexor works its miles ahead of alot of the other ssri's as far as potency goes. Which is also one of its negative points, its so potent that withdrawl from it is pretty painful and scary.
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Old 04-23-2006, 05:36 PM   #6 (permalink)
 
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Isn't different in that effexor is an SSNRI and not just an SSRI? So (and this is just a guess, there are those of you out there that know MUCH more than me) if its affecting more brain chemicals, withdrawal would be more difficult, right? Anyone who knows more or knows for sure, please comment! Thanks!
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Old 04-23-2006, 06:33 PM   #7 (permalink)
 
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Quote:
Originally Posted by christiem
Isn't different in that effexor is an SSNRI and not just an SSRI?
Uh huh.

Quote:
Originally Posted by christiem
So (and this is just a guess, there are those of you out there that know MUCH more than me) if its affecting more brain chemicals, withdrawal would be more difficult, right?
I'm really not sure if that is the reason or not, but Paxil was easy for me to taper off of and Effexor was pretty difficult.
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Old 04-24-2006, 12:44 AM   #8 (permalink)
 
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i took paxil for 2 years and it worked wonderfully. and i probably would of stayed on it if i didn't have to keep upping the dosage. about a year or so later after quitting and swearing i would never touch it again (horrible withdrawal), i tried it again because my pdoc convinced me to - it bombed. my pdoc then had my try effexor - nothing.

i am now on lamictal and am feeling so much better.
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Old 04-26-2006, 08:36 PM   #9 (permalink)
 
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I've been on effexor er for 2 days now and I feel miles different from when I was on paxil. Is it possible to feel effects that fast?
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Old 04-27-2006, 07:15 AM   #10 (permalink)
 
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christiem, I also felt effects after 2-3 days on Effexor. It really caught me by surprise to have it kick in so fast.
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Old 04-27-2006, 09:10 AM   #11 (permalink)
 
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Yes, Effexor can kick in in as little as 3 days for some people, especially if you are switching over from an SSRI (although it usually will take longer). The NRI component is relatively fast-acting.

I have not tried Paxil (don't really want to either), but Effexor worked pretty well for me. Helped a lot with depression. I went up to 150mgs, but stopped. It gave me tinnitus, which I didn't tolerate, otherwise I would have gone up on the dosage.
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Old 05-03-2006, 03:25 PM   #12 (permalink)
 
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I was on paxil for 2 years and now i'm taking effexor. I feel like there real close to the same thing. They both helped me about the same. I would say maybe effexor is a little bit better if any. Also, I have missed a few days worth of doses on both, and the consequences are the same for me; Nausea, dizziness and generally feeling sick.
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Old 05-03-2006, 04:21 PM   #13 (permalink)
 
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Paxil hasn't done anything for me and I've been at 40 mg for a while. Effexor helped me at 150 mg but it made me so, so tired and sweaty. I couldn't handle it.
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Old 05-07-2006, 05:00 PM   #14 (permalink)
 
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20mg of Paxil made me sleep for about 10-11 hours a day which was really crappy..right now I've been on Effexor XR for almost two weeks now..started at 37.5 for a week and have been on 75mg for 10 days with few side effects so far, but not much benefit either. I'll probably keep trying it until my xamples run out and then call my doctor..
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Old 05-07-2006, 05:58 PM   #15 (permalink)
 
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I've been on both, and couldnt continue with either. Paxil I was able to take for a much longer time period, but the weight gain was terrible, and eventually my cholestorol got too high, and they took me off it. I recently took effexor, but only for a month, because my blood pressure shot up.
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Old 05-07-2006, 10:07 PM   #16 (permalink)
 
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Now are we talking about Paxil or Paxil CR, because I found there is a big difference between the two. I did well on Paxil CR, but when it was recalled last year my Dr had to switch me to the non-controlled release tablets. I spiralled downward fast. She referred me to a psychiatrist who switched me to Effexor (I was up to 300mg) and now she's switching me back to the Paxil CR. She thought the Effexor would be better because it might give me more energy during the day. Effexor triggered migraines and appetite loss (I've lost 15 lbs since February & I didn't really want to). And it had no effect on my energy; I can still sleep 15 hours a day after I take it. My psyc also thinks it may have increased my anxiety because my dermatillomania got worse after I started it.

Lupus is right, though, what works well for some might work differently for others. I guess it takes some time to work out the right combo specific to each person's brain chemistry.
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Old 05-07-2006, 10:17 PM   #17 (permalink)
 
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How is Effexor on weight gain?

I run 20mi/week and STILL gained 25-30lbs. Come to think of it, Celexa was almost as bad in terms of weight gain when I was on tfour years ago.

My doctor suggested possibly switching to Effexor now that I am starting to taper off of Paxil a little bit (after being up to 40mg, I am teetering between 20 and 30 on bad days).
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Old 05-12-2006, 09:48 PM   #18 (permalink)
 
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Quote:
Originally Posted by millenniumman75
How is Effexor on weight gain?

I run 20mi/week and STILL gained 25-30lbs. Come to think of it, Celexa was almost as bad in terms of weight gain when I was on tfour years ago.

My doctor suggested possibly switching to Effexor now that I am starting to taper off of Paxil a little bit (after being up to 40mg, I am teetering between 20 and 30 on bad days).
I actually lost my appetite when I was on Effexor. Weight loss is listed as a side effect, but not gain.
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Old 05-12-2006, 09:52 PM   #19 (permalink)
 
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Quote:
Originally Posted by 13times
I'm really not sure if that is the reason or not, but Paxil was easy for me to taper off of and Effexor was pretty difficult.
Really? Tapering off Paxil was hard for me, I experienced headaches and vertigo.
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