I recently read about this combination from a customer review at iherb.com (where I buy most of my supps). He stated that this combo increases GABA so I decided to try it. I had already tried L-Glutamine but it tended to worsen my symptoms (not much though).
For those of you who don't know, L-Glutamine is an amino-acid that is a precursor for both glutamate (the main excitatory neurotransmitter) and GABA (the main inhibitory neurotransmitter), whereas Taurine is a non-essential aminoacid with neuromodulator properties, the most important ones (in this case) being:
1 - It is a GABA agonist.
2 - It can mimick the effects of GABA.
3 - It increases GABA degradation time.
4 - Unlike GABA, it seems to cross the blood brain barrier.
My reasoning was as follows:
1 - L-Glutamine will increase GABA and glutamate.
2 - Taurine will make GABA stay more time in the brain until it is degraded.
3 - Taurine will also dampen the activating effects of glutamate.
It seems to work, but it makes me sleepy to the point i really want to go to sleep. It somewhat resembles the effects of a benzo.
A magnesium supplement can further decrease the activating effects of glutamate at the NMDA receptor.
A must try, but be careful about dosages. I tried 500mg of L-Glutamine plus 500mg of Taurine and it has a strong effects. It could probably be better to start at half those dosages.
EDIT (Another interesting post about Taurine):