"Supplementation of Histidine has been shown to cause rapid zinc excretion in rats with an excretion rate 3 to 6 times normal. Some people take histidine in an attempt to raise their histamine levels. Histamine is released under conditions of higher osmolality (dehydration\salt). Raising histamine may be more effective by adapting the body to a higher osmolality by eating sodium without greatly increasing water intake and taking supplements that help the body adapt to those conditions (zinc\taurine\B1\B12). Histidine supplementation likely tricks the body into believing it is producing less histamine and assumes it is well or overhydrated and is better off without the nutrients used to maintain cellular hydration in a hyperosmotic state. Histidine supplementation however is inadvisable because one of the hallmarks of today's chronic diseases (diabetes, Alzheimer's, Parkinson's) is zinc depletion."
"Histidine can convert to histamine, which is a major neurotransmitter in your brain & throughout parts of your nervous system. However, histidine intake does not always increase brain histamine, Low brain histamine levels are associated with hyperactivity, mania, paranoia, hallucinations, & abnormal thoughts. Many brain functions of histamine are poorly understood but it is thought to participate in the secretion of 2 hormones, (prolactin & antidiuretic). It is thought to aid temperature regulation & be involved in the control of automatic nerve response in the central nervous system.*
Vitamin E deficiency will cause the depletion of histidine from muscles. Histidine is involved with the regulation of zinc levels in your body. If zinc is excessive it will lower histidine; if histidine is excessive it will decrease zinc levels. But appropriate levels of histidine enhance zinc levels.* "
Salt is the raw material needed to manufacture stomach acid. Stomach acid is hydrochloric acid that is necessary to digest food, ensure absorption of minerals, activate pepsin (protein digestive enzyme produced by the stomach) and activate the "intrinsic factor" necessary to absorb vitamin B12.
Restricted salt intakes will make you heat intolerant and over the long term will result in digestive problems including belching, burping, intestinal gas and G.E.R.D. (gastro esophageal reflux disease).
Restricted salt diets with the resultant hypochlorhydria (low stomach acid) will increase risks of nutritional deficiency diseases including obesity (reduced absorption of minerals increases the munchies), diabetes, high blood pressure, arthritis, osteoporosis, kidney stones, cataracts, fibromyalgia, etc.