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Old 11-24-2008, 01:50 PM   #1 (permalink)
 
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Default Balance the Immune System (Th1/Th2)

http://www.ei-resource.org/articles/...-(th1%10th2)-/

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CFIDS patients are Th2 activated. This means they over-respond to toxins, allergens, normal bacteria and parasites, and UNDER-RESPOND to VIRUSES (like the epstein barr virus), YEAST (like Candida), cancer and intracellular bacteria (Like that of Lyme's disease). Dr. Cheney suggests six products that can help rebalance the immune system.



Dr. Cheney explained that the immune system has two different modes of attack, based on the type of invader. One is Th1 (T Helper 1). It goes after organisms that get inside our cells ‚ intracellular pathogens. It is also known as cell-mediated immunity. The other is Th2 (T Helper 2). It attacks extracellular pathogens ‚ organisms that are found outside the cells in blood and other body fluids. Some call this humoral or antibody-mediated immunity. A healthy immune system is dynamic, able to switch back and forth as needed, quickly eradicating one threat and then resting before responding to the next.



(Dr. Cheney began this conversation by drawing a large inverted "V". At the top point he wrote "Th0", which he called "Th naught". The left arrow pointed down to "Th1" and the right arrow to "Th2". The arrow on the right was much darker and thicker, indicating that CFIDS patients are Th2 activated.)



Th0 are the naive, or unformed, cells of the immune system. They are resting, just waiting for an invader. When infection occurs, they convert to either Th1 or Th2, depending on the type of threat. When the resting cell is exposed to a virus, cancer, yeast, or intracellular bacteria (like mycoplasma or chlamydia pneumonia), the Th1 response is initiated. (Dr. Cheney wrote these organisms beside the left arrow.) The weapons of the Th1 system include cytotoxic T cells and Natural Killer (NK) cells. (Cheney drew these below "Th1".)



On the other side are normal bacteria, parasites, toxins, and allergens. (Likewise written beside the right arrow.) These trigger a predominately Th2 response. Its weapons include eosinophiles (Eos), polymononuclear cells (PMN), and antibody secreting cells (Ab). (Likewise written below "Th2".)



How does the naive cell know which pathway to take? It depends on the cytokine information received. The presence of any organism from the left side triggers production of a cytokine called Interleukin 12. IL-12 causes the Th0 cell to move down the Th1 path. On the other hand, organisms on the right side trigger the production of Interleukin 10 (IL-10), which causes the Th0 cell to move down the Th2 path. (Cheney added small vertical dotted lines on each side, pointing upward to "IL-12" on the left and "IL-10" on the right. He then drew horizontal dotted arrows from "IL-12" and "IL-10", each pointing inward toward the "Th0", indicating that these cytokines determine whether it will become Th1 or Th2.)



Cheney said this is the point where it gets very interesting. Viruses, especially herpes viruses like EBV, CMV and HHV6, make proteins that mimic IL-10. The virus deceives the immune system into thinking that the threat is coming from the opposite side! So the immune system shifts from the Th1 mode that attacks viruses to the Th2 mode that does not. The virus increases its chances of survival by diverting the immune system. It is now thought that many, if not most, pathogens have this ability. (To represent this effect, Cheney drew a horizontal arrow about half way down the inverted "V", originating from the left side and pointing toward, but not quite touching, the right side. The line was labeled "IL-10 like peptides". Below it he drew a similar arrow from the right side that almost reached the left side. It was labeled "IL-12 like peptides".)



Researchers have demonstrated that most CFIDS patients end up stuck in Th2 mode. This has several consequences. When the Th2 system activates, it blocks the Th1 system. This suppresses the Th1 weapons, particularly NK function. Accordingly, there is also an increase in the Th2 weapons - the white cells and antibodies. Most notable is increased antibody production. Dr. Cheney said that if you measure antibodies to anything a CFIDS patient has ever been exposed to, they will very likely be elevated. (At this point he drew small arrows beside the "weapons": They pointed down on the left side to indicated suppression / lower levels; and they pointed up on the right side to indicate activation / higher levels.)



Cheney notes that other problems ensue. Patients get into trouble on both sides: they overreact to things on the right side and under-react to those on the left. When they are Th2 activated, they no longer have the defense mechanisms to keep dormant all the things they caught in the past. They cannot suppress or control them anymore, and the EBV, chlamydia pneumonia, CMV, etc. reactivate. The yeast also begins to appear.



The only defense against being eaten alive at this point is RNase L. (For more information about RNase L, see The Three Phases of CFIDS and other articles in the Cheney section of our website.) RNase L cannot kill any of these things. It only stops them from reproducing. According to Cheney, "It's a line in the sand saying 'No more replication', and it waits for Th1 to come and kill them. But Th1 never comes. RNase L sits there and grinds away, possibly going up and down as the pathogens activate and reactivate. But they never get wiped out. RNase L holds the line, waiting for the cavalry that never arrives."



While it is valiantly trying to hold the line, it is also chewing up human messenger RNA, inhibiting all the enzymes in the body, disrupting protein synthesis, and generally making patients miserable. As RNase L grinds away, it eventually shifts into "after-burner" desperation mode - the more powerful and deadly low molecular weight form discovered in CFIDS patients by Suhaldonik.



Cheney commented "RNase L is a very good anti-cancer defense. So as long as you're involved in this scenario, you don't get cancer. But a lack of growth hormone will wipe out RNase L, and we now know there is profound loss of growth hormone in CFIDS. Growth hormone is responsible for protein synthesis, and RNase L is a protein. So if you lose growth hormone, you lose protein synthesis, including RNase L. That may explain why, as the disease wears on and you get more injury, you stop seeing high levels of RNase L. You can't make it anymore."



He believes this is a very scary situation. Patients are Th2 activated and Th1 suppressed. The things on the left come out and there is nothing to stop them. There is no Th1, and eventually no Rnase L. He also believes patients need to balance the immune system - to push it a little more towards Th1. That way they will lose some of the overreaction on the right and gain some control on the left.



Cheney recommends the following to help shift the immune system from one mode to another. They are called "right to left shifters". Three of them are published, or near publication.



1) Kutapressin (published, prescription)
Kutapressin is an immune modulator and a broad spectrum anti-viral. Dr. Cheney has found that it is most effective when the dose is varied or "pulsed". The dose should vary from 1 to 4 cc daily; see the section on Isoprinosine for this theory. Dr. Cheney strongly suspects Ampligen is a right-to-left shifter also. He has said in the past that Kutapressin is rather like a weak form of Ampligen.



2) Isoprinosine (published, prescription)
Published for use in CFIDS, this anti-viral enhances NK function. Dr. Cheney believes it would also be good against intracellular bacteria since it is a Th2 - Th1 shifter. It appears to raise IL-12 and lower IL-10, which turns off Th2 and turns on Th1.



It is also called Imunovir and is very nontoxic, very safe. It has been approved in Europe and Canada for just about any viral infection for 18 years. It is not approved in the US (for political reasons, not safety concerns) but is easy to get from Ireland with a prescription. Contact Newport Pharmaceuticals at 353-1-890-3011, fax them at 353-1-890-3016 or email them at info@newport-pharma.comThis e-mail address is being protected from spam bots, you need JavaScript enabled to view it


Week one, take 6 tablets a day, Monday through Friday, and none on the weekend. Week two, take 2 tablets a day, Monday through Friday, and none on the weekend. Repeat this cycle. But do not treat every month. Do two months on and then one month off of this "pulsing" dose. This medicine works best when you do not treat regularly. If you treat continuously at the same dose, it stops working. It is an immune modulator, and Dr. Cheney suspects all immuno-modulators are like this. If taken continuously they stop working. The dose must vary so the immune system never knows what to expect.
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Old 11-24-2008, 01:52 PM   #2 (permalink)
 
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Continued...

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3) Pine Cone Extract (supplement
, www.pinextra.com)
Cheney said, "They make a tea from this in Southern Japan and they have significantly reduced cancer rates. It's thought to work at the gene level in lymphocytes, where it turns on IL-12. It also shuts down IL-10 at the gene level, and that causes a shift towards Th1. Pine Cone extract is expensive, but at just 10 drops a day (in the morning), of all the possibilities, it's probably the cheapest per day." It is called PineExtra, and 1 oz is about $60, but it lasts a long time.



4) Earth Dragon Peptides (supplement, http://www.nutricology.com, http://www.needs.com)
Earth Dragon is round worm peptides. It causes a shift to the left, and is believed to be very similar to IL-12. There has been a huge surge in the use of ED peptides to treat Inflammatory Bowel Disease, specifically Crohn's Disease. One professor at UNC treats all his Crohn's Disease patients with Earth Dragon. It is very non-toxic and safe. This is a good choice for those who want to balance their immune system and also have bowel problems. Earth Dragon is about $36 for 150 caps. The dose is two a day.



5) Heparin (prescription)
Heparin is a Th2 - Th1 shifter. One advantage for many patients is that it is also an anticoagulant. Dr. Cheney only recommends this if a patient has a coagulopathy. About half of his patients do, according to the ISAC test. (See http://www.hemex.com or "Blood Related Disorders in CFS/FM.")



6) Formula 560 Transfer Factor (to be published, supplement, http://www.immunitytoday.com)
Formula 560 is an immune modulator. Dr. Cheney likes this product. It reportedly works against HHV6 and Lyme Disease, as well as other problems. It costs about $585 for the first three months, then the dose drops one-third. It averages out to about $130 a month for the first six months, and $65 thereafter. (The cost of this product has reported dropped since this was first published.)
NOTE: Pro Health is an additional source for the Transfer Factor products (we carry the Formula 560 as well as the exact same product and from the same manufacturer that we call Transfer Factor 6000 and sell it for less).



Which should you use? Cheney recommends that you pick one and see what it does to your NK function. It is a question of whether it will work and how much it costs. NK levels will rise if there is a shift from Th2 towards Th1. Before beginning one of these products it is best to get a baseline on NK function. Then test again after having been on the product for one to three months. Dr. Cheney uses the lab of Mary Ann Fletcher, an NK specialist and colleague of renowned researcher Nancy Klimas, at the University of Miami. Her lab is no more expensive than commercial labs, and is top quality. Cheney emphasizes that you must have a quality lab do this test: do not use just any lab. For test information, phone 305-243-6288 or fax 305-243-4674. The test is called "Natural Killer Cell Function Assay" and costs $350.
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Old 11-24-2008, 02:33 PM   #3 (permalink)
 
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The point here is, no matter how many anti-fungal or anti-candida supplements we buy. No matter how many vinegar enemas we perform, we will never rid ourselves of candida effectively until we regulate the function of the immune system.
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Old 11-24-2008, 03:14 PM   #4 (permalink)
 
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Here's another good link which explains this posted by proximo a while back

http://www.diagnose-me.com/cond/C104791.html



http://grouppekurosawa.com/blog/2005_03_12_

"One of the classic immunological dysfunctions identified rapidly after HIV infections is a shift from the TH1 or cell mediated immune response to the TH2 or antibody based immune response. The nature of this shift has never been conclusively explained. One thing is certain...only TH1 dominant immune responses can clear the HIV and other viruses from their hiding places. Could zinc status be the "switch" that determines the direction of the immune response when confronted with specific pathogens?....

.....in a zinc deficient state, the TH1 response will be impaired, while the TH2 response will be dominant by default. "


http://www.ncbi.nlm.nih.gov/entrez/q..._uids=10944485
Effects of zinc deficiency on Th1 and Th2 cytokine shifts.

"Zinc deficiency in an experimental human model caused an imbalance between Th1 and Th2 functions. "
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Old 11-24-2008, 06:03 PM   #5 (permalink)
 
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Here's more info. on this issue posted by proximo and I over the last few months:

Microbiology Section, Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Italy.

Resistance to Candida albicans infection in mice results from the development of T helper (Th) type 1 cell responses. Cytokines produced by Th1 cells activate macrophages and neutrophils to a candidacidal state. The development of Th2 responses underlines susceptibility to infection, because cytokines produced by Th2 cells inhibit Th1 development and deactivate phagocytic effector cells. With the recognition of the reciprocal influences between innate and adaptive Th immunity, it appears that the coordinated action of these two lines of immune defense is required to efficiently oppose the infectivity of the fungus and to determine its lifelong commensalism at the mucosal level.

------

http://iai.asm.org/cgi/content/full/68/9/5126?

Interleukin 18 Restores Defective Th1 Immunity to Candida albicans in Caspase 1-Deficient Mice

Microbiology Section, Department of Experimental Medicine and Biochemical Sciences, University of Perugia, 06122 Perugia, Italy,1 and Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut 065102

Received 22 February 2000/Returned for modification 1

May 2000/Accepted 20 June 2000

------

T-helper cells are part of the immune system. These are a type of white blood cell. There are two types, 1 and 2. 1 works with cellular immunity. It's the part of the immune system that is activated right away during an infection. It's slower and uses no antibodies, but it activates macrophages. Type 2 is used by the Humoral system. This stimulated B-cells to make antibodies.

According to those links, increased activiy in Th 1 is helps fight candida while increase activity in th2 doesn't. So, in theory, anything that elevated Th1 activity, will help you fight candida.

-----

This th1 th2 imbalance is very important. and you know what else increases th1, SILICA.

References?

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too little Th1 acivity and too much Th2 contributes to aging.

References?

-----

"A failure of the Th1 arm of the immune system and an overactive Th2 arm is implicated in a wide variety of chronic illnesses. These include AIDS, CFS, candidiasis, multiple allergies, multiple chemical sensitivities (MCS), viral hepatitis, gulf war illness, cancer and other illnesses. If these two arms of the immune system could be balanced by stimulating Th1 and
decreasing Th2, then many of the symptoms associated with these chronic illnesses would diminish or disappear and we would have found the answer to immune restoration and balance or the equivalent of a cure."

Found this,

"Transfer Factor, Th1 And Th2

If at all possible, you want to get the yeast under control with things that simulate the
immune system without damaging the liver. Such an agent is the specific transfer factor that Hugh Fudenberg, MD is working with. Transfer factor “ educates” the immune system to express its Th1 (T-cell Helper type 1) response. The Th1 immune response is needed to control viruses, protozoa, and fungus. Transfer factor is a component of mother’ s
first milk (colostrum) that provides immune system messenger molecules. If a transfer factor
is “ specific,” that means it contains immune components specific to a particular pathogen. For
example, if you have a particular strain of yeast overgrowth, a specific transfer factor product
could be made that targets that strain of yeast. However, I don’ t know of any products that
target different strains of yeast that are available to the public at this time."

So, transfer factor, also known as proline-rich polypeptides favors TH1 over th2. Also, Lactoferrin binds to iron making it unavailable to pathogens. This got me thinking. Both these components are found in Colostrum. Colostrum all has immunoglobulins and a whole host of other things. Transfer factor is HELLA expensive and so is lactoferrin. So, why not just take
colostrum???

-------

There are many natural agents available to help restore balance in an underactive Th1 arm. These include:

Omega-3 fatty acids, monounsaturated fats found in olive and hazelnut oils, vitamin A cod liver oil, l-Glutamine, Silica, digestive enzymes, friendly intestinal flora or soil based organisms (SBOs), ginseng (Red Korean or concentrated Siberian Ginseng extract), chlorella (spirulina and some other sea vegetables may have similar benefits), thyroid hormones, garlic (raw or aged extract), l-Glutathione (or products that raise levels), DHEA or AED (androstendiol), UV-A light, vitamin E, transfer factor (antigen specific) - protein immunomodulators extracted from colostrum, colostrum, low dose naltrexone, IP6, lentinian and certain other mushrooms, Thymus extracts, licorice root, dong quai, beta 1,3-glucan, noni, neem, gingko biloba, exercise, water (to aid detoxification), a positive attitude, the ability to forgive and be compassionate, and having long-term goals.

http://www.diagnose-me.com/cond/C104791.html
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Old 11-24-2008, 06:48 PM   #6 (permalink)
 
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Supplements that enhance TH1 immunity.

-Pineextract (web)
-Zinc
-Earth Dragon (amazon)
-LDN
-Thymic immune Factor (lef)
-Astragalus
-AHCC may increase Natural Killer (NK) Cell activity
-NK immune (source naturals)
-IP6
-Rice Bran Arabinoxylan Compound
-Epicor
-beta glucans
-Coconut/Olive oil
-Increased Glutathione
-Glutamine
-Colostrum
-Ginkgo
-Garlic (Fresh and aged)
-Chlorella
-Noni
-neem
-DHEA
-Silicon
-IP6
-Vitamin E
-Heparin
-Transfer factor


FAvors Th2 (need references to prove)
-Fish oil
-Vitamin A
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Old 11-24-2008, 07:19 PM   #7 (permalink)
 
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Thanks Beggiota

This topic definitely requires its own thread.

Th1 th2 imbalance is very important for health candida, anxiety, hypoglycemia and other problems we have.

I can't believe how much progress we have made so far...

I think it is just a matter of time and determination from now on
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Old 11-24-2008, 08:31 PM   #8 (permalink)
 
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Quote:
Originally Posted by proximo20 View Post
I can't believe how much progress we have made so far...

I think it is just a matter of time and determination from now on
I agree. You caught on to this issue early on. I needed to fill in the missing pieces in between to put everything together. Now I'm totally on-board with you.

I think the focus, aside from therapeutic maintenance for things like SAD, indigestion and cognitive problems, should be directed towards the diagnosis of a chronic pathogen and the regulation of the immune system.

From what I'm reading, regulating the th1/th2 function seems to revolve around the thymus gland and doing whatever possible to boost it's function including normalizing vitamin D levels, and maybe using thymus extract.

However, one question still remains.....why is there an imbalance of our immune system??

That's the next step. I hope it's something we already know, like a heavy metal toxicity.

This is one the supplements listed above. Looks promising. http://pine-extra.com/

I'm also trying to get my hands on LDN. But that's going to be hard to come about.

another product http://www.lef.org/Vitamins-Suppleme...e-Factors.html

http://www.proboostmed.com/faq.html

All this stuff, candida, mercury, chronic illness, is all related. Some issues take precedent, like chelating heavy metals from our bodies, removing amalgams, etc. but I think fighting candida is a lost cause unless your immune system is regulated. That said, I'm still doing to to do a 5 day fast/colon cleanse followed by an ACV irrigation...just to see what comes out

I've been on a sort of vacation the last few months. I start school in January once again and I'll have to fly back to the caribbean. This means no time to research and worse, no access to any kind of supplements. So whatever I do, I'll have to do it pronto
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Old 11-25-2008, 12:24 AM   #9 (permalink)
 
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Quote:
CFIDS patients are Th2 activated. This means they over-respond to toxins, allergens, normal bacteria and parasites, and UNDER-RESPOND to VIRUSES (like the epstein barr virus), YEAST (like Candida), cancer and intracellular bacteria (Like that of Lyme's disease).
Quote:
FAvors Th2
-Fish oil
-Vitamin A
No wonder I've been getting indigestion and peeing more frequently lately since I've upped my dosage of fish oil and included vitamin A in my supplement regimen. I've been peeing every 20 min and farting and burping every 30 min lately. It must be the candida acting up cause i've been wreaking havoc on the balance of my immune system.

I also have a benign brain tumor too, so I better start taking more of the the supplements that enhance Th1 immunity and stop taking fish oil and vitamin A for the time being

Anyway, thanks sooo much for the info!!!!
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Old 11-25-2008, 04:08 AM   #10 (permalink)
 
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Thanks for the great info. I have white spots on the finger nails and there is only 2 explanations. One is calcium deficent. Well I consumed alot calcium for some days and they didn't go. Those white spots on my finger nails must show that I am zinc deficient.

Thanks.
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Old 11-25-2008, 05:56 AM   #11 (permalink)
 
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Quote:
Originally Posted by ju_pa View Post
Thanks for the great info. I have white spots on the finger nails and there is only 2 explanations. One is calcium deficent. Well I consumed alot calcium for some days and they didn't go. Those white spots on my finger nails must show that I am zinc deficient.

Thanks.
From http://www.acu-cell.com/dis.html

White Spots on Fingernails: General mineral imbalance, low calcium, low iron, (not low zinc).

But again you might want to google it. Acu-cell is a nice site to see which minerals causes which disorders.
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Old 11-25-2008, 10:48 AM   #12 (permalink)
 
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http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

"Experimentally, Th1 polarization is readily transformed to Th2 dominance through depletion of intracellular glutathione, and vice versa. Mercury depletes glutathione and polarizes toward Th2 dominance. "

This part of the study says fish oil doesn't affect th1/th2 balance

"Several nutrients and hormones measurably influence Th1/Th2 balance, including plant sterols/sterolins, melatonin, probiotics, progesterone, and the minerals selenium and zinc. The long-chain omega-3 fatty acids EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) significantly benefit diverse inflammatory and autoimmune conditions without any specific Th1/Th2 effect."


sparkationsgirl,

If fish oil is giving you indigestion, you're probably not digesting it right. Consider using some digestive enzymes with Lipase or Ox bile and see it that helps. Don't stop fish oil! It's the single best thing you can take for your body.


"t now seems that Th1 cells and the pathway they dominate are heavily reliant on interferon-gamma (IFN-gamma), and to a lesser extent interleukin-2 (IL-2) and interleukin-12 (IL-12). Th2 cells are most heavily reliant on interleukin-4 (IL-4) and sometimes interleukin-5 (IL-5) as well."
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Old 11-25-2008, 11:17 AM   #13 (permalink)
 
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Quote:
sparkationsgirl,

If fish oil is giving you indigestion, you're probably not digesting it right. Consider using some digestive enzymes with Lipase or Ox bile and see it that helps. Don't stop fish oil! It's the single best thing you can take for your body.

oh okay, good thing you cleared things up. anyway, i will take digestive enzymes to see whether it helps with the indigestion!
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Old 11-25-2008, 12:50 PM   #14 (permalink)
 
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Great job!! Very interesting reading despite my severe brain fog today*!! :-)

My candida is getting worse by the minute...these are some great tips. The hypoglycemia turns into severe anxiety for several hours at a time!!Lovely
I also wanted to add that when I take too much fish oil I get hyper. Wonder what that is about...

What about molybedeum (gotta love my spelling) any thoughts on taking that?


In the meantime I am going to try Swedish Bitters for enxymes and will report back. I couldn't take the other enzymes bromelein papain etc. Although I am going to Try Papain on it's own. But I am definately going to try some of the above stuff!!
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Old 11-25-2008, 12:54 PM   #15 (permalink)
 
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Also wanted to ask how many of you are taking q10? I am now positive that it was the 30 mg q10 and the magnesium that took me from a typical CFS to having a normal energy level. I took carnitine for 3 months but it was not until I´took the q10 that Igot a normal energy level back. I can't handle more thant 30 mg because ya you now the hyper wired feelings come......
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Old 11-25-2008, 05:18 PM   #16 (permalink)
 
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http://www.bulkmsm.com/DMG/web12.htm

DIETARY FACTORS THAT SUPPORT Th1 CYTOKINES

Omega 3 fatty acids (N3) found in cold water fish reduce IL-6, tumor necrosis factor and support DTH. Oleic acid, found in olive oil (cold pressed) and hazelnut oil, vitamin A and L-glutamine increases IgA and improve mucosal integrity. The use of two heat-treated strains of lactobacillus - L. Plantarum and L. Casei induces a strong IL-12 response and increases IFN-gamma and strengthen the systemic immune response against all intra-cellular infections and even cancers. The intestinal flora Bifidobacterium longum also increases IgA and improves mucosal immunity. Silica reduces excess IgG and this improves NK function and improves the integrity of the skin and mucus membranes.

1. Omega 3 fatty acids (DHA/EPA) found in all cold water fish, especially in salmon, sardines, mackerel, halibut and trout. Supplements: Max DHA (Jarrow Formulas) Salmon oil capsules, Cod liver oil. DHA - 1500 to 2500 mg daily and EPA - 500 to 1000 mg daily.

2. Oleic acids (Monounsaturated). Best choice is cold pressed olive oil (a therapeutic dose is 4 tablespoons daily), 2nd best - hazelnut or filbert oil. Also green and ripe olives, filberts and hazelnuts. Third - almonds and almond oil.

3. Vitamin A - 2 tablespoons of cod liver oil daily (Dale Alexander emulsified) or 25,000 i.u. daily of Vitamin A with vitamin D plus 1/2 to 1 lb daily of any of the following sourcesof carotenoids: cooked carrots, squash, pumpkin and sweet potatoes (yams).

4. L-Glutamine - 10 to 20 grams or more daily or as directed. Maintenance: 2000 mg daily.

5. Silica - One serving of cooked oatmeal or millet daily and/or the herb horsetail (3 caps 2X) or Bio-Sil (Jarrow Formulas) - the most bio-available form - 10 drops 3 times a day. Maintenance - 10 drops once a day.

6. L-plantarum and/or L casei and B. longum - up to 1 teaspoon of powder 2 or 3 times a day. After 7 to 14 days of use, you may only need to use this 3 days per week.

Other products like Neem, soil based organisms (SBO’s) and supplemental factors that replace glutathione help Th1 responses. The more of the above items you use, the faster you will see results. It is critically important to completely avoid processed vegetable oils and foods cooked with them and other factors that promote Th2 cytokines.
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Old 11-25-2008, 05:19 PM   #17 (permalink)
 
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DIETARY FACTORS THAT INCREASE Th2 CYTOKINES

The three most common factors that drive Th2 cytokine responses are:

1. Faulty digestion leading to absorption of partially digested and unusable proteins and other food particles (increases IgG and IgE antibody responses that are directed against these foreign food particles). Here we see the therapeutic benefits of digestive enzymes, eating slowly mixing lots of saliva with food and eating only when hungry).

2. White sugar and glucose and all processed foods containing these (Coke, canned soda, candy bars, cake, pie, sweet rolls etc.) - directly weakens the functioning of macrophages, natural killer cells and other white blood cells and weakens systemic resistance to all infections.

3. Consuming trans-fatty acids found in most heated and processed vegetable oils (soy, canola, safflower, corn and sunflower) that are high in n-6 fatty acids (linoleic) and food products made with them (i.e. french fries and potato chips). Vegetable oils high in linoleic trans-fatty acids stimulate IL-6 and depress delayed type hypersensitivity (DTH) thus weakening CD8 Killer-T cell activity. The trans-fatty acids are twisted out of their normal “cis” shape and produce cell membranes that are porous and vulnerable to viral infections.

For example, persons who consume canned soda (i.e. Coco-cola) and french fries daily and are already immune compromised will worsen their condition by these dietary choices. Many other factors that stimulate a Th2 response will be discussed later. Some herbs (Echinacea and Astragalus) stimulate both Th1 and Th2 cytokines.
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Old 11-25-2008, 05:23 PM   #18 (permalink)
 
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a. Cayenne - 1 or 2 capsules taken before meals stimulates hunger and digestive enzymes. (support digestion of nutrients for mucosal membrane integrity)

b. Lemon juice or apple cider vinegar - taken with meals stimulates hydrochloric acid for protein digestion. (support digestion of nutrients for mucosal membrane integrity). Vinegar, any type, kills HIV and may other pathogens.

c. B vitamins - several kinds are needed to support hydrochloric acid production that is needed for protein digestion. B6 is very important for CMI.

d. Magnesium - needed by pancreas to produce pancreatin - used to digest proteins.

12. Garlic - raw or aged extract - promotes NK function and IL-2. Raw garlic kills HIV, many kinds of fungus and bacteria including MAC.

13. L-Glutathione - promotes antigen presentation and stimulates CD8 CTL’s. An antioxidant, it neutralizes free radicals. Alpha Lipoic acid, selenium, NAC, cold processed whey proteins, certified raw milk and L-glutamine support increased Glutathione levels.

14. DHEA or AED (androstendiol). - increases IL-2, IFN-gamma and decreases IL-6 and 10.

15. Acupuncture (points ST36, LI11 and RN6) increase IL-2, IFN-gamma and NK function.

16. UVA light - promotes IL-12.

17. Vitamin E - increases IL-2, NK function and IFN-gamma. Reduces NF-kappa B.

18. Transfer factor (antigen specific) - protein immuno-modulators extracted from colostrum from immunologically stimulated animals that promotes DTH and specific immunity to certain antigens (viruses etc.).

19. Colostrum - contains IgA - promotes mucosal immunity and immunity to specific antigens to which the animal was exposed.

20. Naltrexone - promotes NK function and resistance to candida albicans, thus reducing Th2 cytokines.

21. IP6 - found in brown rice and corn - promotes NK function.

22. NK911 - a transfer factor that stimulates NK function.

23. Lentinian and certain other mushrooms - promote Th1 cytokines and NK function.

24. Thy-Mate and thymic factors (Bio-Pro thymic Protein A) - increases IL-2 and T cell counts.

25. DNCB - promotes DTH and CD8 CTL activity

26. Licorice root and Dong Quai - reduces antibody production.

27. Beta 1, 3 glucan - found in the common yeast and in oats and oat sprouts/rye sprouts - stimulates macrophage and neutrophil function. Note: may also spike IL-6 levels indicating a cross-regulatory role.

28. Noni -Tahitian - 2 tablespoons twice daily - promotes NK function and immunity against cancer.

29. Neem - promotes IFN-gamma and increases CD8s - also, a powerful antiviral, antifungal and antibacterial herb.

30. Gingko Biloba - reduces cortisol production that suppresses Th1 cytokines.

31. Exercise - aerobic - light and fun. Walking, gardening, dancing, sports. increases endorphin levels - improves NK function - removes toxins from body.

32. Water- Drink 8 to 12 glasses daily - removes toxins - reduces stress on adrenals, liver and kidneys.

33. Positive attitude and prayer. - ability to forgive, compassionate, willingness to help others. Long term goals, not just daily and a will to live. Reduces stress on the adrenal glands.
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Old 11-25-2008, 05:27 PM   #19 (permalink)
 
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13 TYPES OF ENEMAS

Thirteen types of enemas being considered are

1. Garlic and apple cider vinegar.

2. Aloe vera juice - 1 cup to a enema bag filled with water

3. Witch Hazel - 1 tbsp in a cup of water to make a tea.

4. Lemon Balm - 1 tbsp in a cup of water to make a tea.

5. Chlorophyll - 1/4 cup to an enema bag.

6 Yogurt - plain/sour - add one cup to a 2 qt enema bag.

7. Buttermilk - 1 cup to an enema bag.

8. Ozonated water enema.

9. Urine retention enema. Add one cup of more of your first morning urine to the enema bag and fill the balance with water.

10. Coffee retention enemas.

11. Bitter melon.

12. Black walnut.

13. Charcoal. 1 heaping teaspoon to an enema bag filled with water (about 10 capsules broken open)

The Witch Hazel or Lemon Balm tea is then added to the enema bag and the balance is filled with lukewarm water.

My initial suggestion is to rotate these enemas every 7 days. The anti viral enemas are Garlic and vinegar, Lemon Balm, chlorophyll, charcoal, Bitter Melon, ozonated water and urine. Anti-parasitic enemas are garlic and black walnut. Anti-fungal enemas are garlic, vinegar and black walnut. Enemas to heal the mucus membranes are aloe vera, buttermilk, yogurt and witch hazel. Enema to detoxify the liver is coffee. Enema to implant good bacteria is yogurt. Enema to absorb toxins, viruses and bacteria is charcoal.
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Old 11-25-2008, 05:29 PM   #20 (permalink)
 
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SILICA - an anti-viral and immune booster

Silica is found in horsetail and in whole grain foods - the fiber portion. As a supplement, silica gel is sold over-the-counter; it is manufactured from crystalline quartz. A book called “SILICA - THE AMAZING GEL, by Klaus Kaufman, reports on a case where silica gel applied topically cleared a herpes lesion in 5 days. The author also reports that silica has been used to successfully treat tuberculosis, warts, intestinal infections and increases immunity to cancer as well as stimulates phagocytes (macrophages and neutrophils) and lymphocytes (T cells), claims that are documented from several sources. In Positive Health News, Report No 17, I reported on scientific research that indicates that silica decreases IgG, an immunoglobulin that when in excess diminishes Natural Killer cell activity.

In a surprising discovery, I have read several scientific articles about PCR testing for quantitating HIV particles that mention “silica” and imply that silica particles are used to bind to the HIV RNA proteins to help with the counting of the amount of HIV RNA plates in the blood serum. Another article mentioned “silica-immobilized” in references to Staphylococcus proteins. Silica may immobilize viruses by binding to their proteins. With its ability to bind to viral proteins, it is curious why silica has not been tested as a direct antiviral agent in controlled studies.

I have talked to many persons affected by AIDS and CFIDS who reports excess IgG in their lab reports. Excess IgG keeps the immune system locked in the TH2 cytokine mode. Silica could turn out to be an important discovery as both an anti-viral mineral and an immune modulator to improve NK function and decrease IgG and TH2 cytokine levels. Based on this research, it is more probable than possible that silica will provide immunological benefits for persons affected by AIDS, CFIDS and cancer.

Food sources of silica: Silica is found abundantly in the herb horsetail, millet, oats and the bran portion of whole grains and in onions and red beets. As a supplement, it is sold in health food stores as “Silica Gel.” A highly bio-available form of silica is Bio-Sil by Jarrow Formulas. Kaufman reports in his book that in Russia, a treatment for tuberculosis is to consume 20 grams (about 3/4 ounce) of pureed millet daily which provides 100 mg of soluble silica.
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