Here's more info. on this issue posted by proximo and I over the last few months:
Microbiology Section, Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Italy.
Resistance to Candida albicans infection in mice results from the development of T helper (Th) type 1 cell responses. Cytokines produced by Th1 cells activate macrophages and neutrophils to a candidacidal state. The development of Th2 responses underlines susceptibility to infection, because cytokines produced by Th2 cells inhibit Th1 development and deactivate phagocytic effector cells. With the recognition of the reciprocal influences between innate and adaptive Th immunity, it appears that the coordinated action of these two lines of immune defense is required to efficiently oppose the infectivity of the fungus and to determine its lifelong commensalism at the mucosal level.
Interleukin 18 Restores Defective Th1 Immunity to Candida albicans in Caspase 1-Deficient Mice
Microbiology Section, Department of Experimental Medicine and Biochemical Sciences, University of Perugia, 06122 Perugia, Italy,1 and Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut 065102
Received 22 February 2000/Returned for modification 1
May 2000/Accepted 20 June 2000
T-helper cells are part of the immune system. These are a type of white blood cell. There are two types, 1 and 2. 1 works with cellular immunity. It's the part of the immune system that is activated right away during an infection. It's slower and uses no antibodies, but it activates macrophages. Type 2 is used by the Humoral system. This stimulated B-cells to make antibodies.
According to those links, increased activiy in Th 1 is helps fight candida while increase activity in th2 doesn't. So, in theory, anything that elevated Th1 activity, will help you fight candida.
This th1 th2 imbalance is very important. and you know what else increases th1, SILICA.
too little Th1 acivity and too much Th2 contributes to aging.
"A failure of the Th1 arm of the immune system and an overactive Th2 arm is implicated in a wide variety of chronic illnesses. These include AIDS, CFS, candidiasis, multiple allergies, multiple chemical sensitivities (MCS), viral hepatitis, gulf war illness, cancer and other illnesses. If these two arms of the immune system could be balanced by stimulating Th1 and
decreasing Th2, then many of the symptoms associated with these chronic illnesses would diminish or disappear and we would have found the answer to immune restoration and balance or the equivalent of a cure."
"Transfer Factor, Th1 And Th2
If at all possible, you want to get the yeast under control with things that simulate the
immune system without damaging the liver. Such an agent is the specific transfer factor that Hugh Fudenberg, MD is working with. Transfer factor “ educates” the immune system to express its Th1 (T-cell Helper type 1) response. The Th1 immune response is needed to control viruses, protozoa, and fungus. Transfer factor is a component of mother’ s
first milk (colostrum) that provides immune system messenger molecules. If a transfer factor
is “ specific,” that means it contains immune components specific to a particular pathogen. For
example, if you have a particular strain of yeast overgrowth, a specific transfer factor product
could be made that targets that strain of yeast. However, I don’ t know of any products that
target different strains of yeast that are available to the public at this time."
So, transfer factor, also known as proline-rich polypeptides favors TH1 over th2. Also, Lactoferrin binds to iron making it unavailable to pathogens. This got me thinking. Both these components are found in Colostrum. Colostrum all has immunoglobulins and a whole host of other things. Transfer factor is HELLA expensive and so is lactoferrin. So, why not just take
There are many natural agents available to help restore balance in an underactive Th1 arm. These include:
Omega-3 fatty acids, monounsaturated fats found in olive and hazelnut oils, vitamin A cod liver oil, l-Glutamine, Silica, digestive enzymes, friendly intestinal flora or soil based organisms (SBOs), ginseng (Red Korean or concentrated Siberian Ginseng extract), chlorella (spirulina and some other sea vegetables may have similar benefits), thyroid hormones, garlic (raw or aged extract), l-Glutathione (or products that raise levels), DHEA or AED (androstendiol), UV-A light, vitamin E, transfer factor (antigen specific) - protein immunomodulators extracted from colostrum, colostrum, low dose naltrexone, IP6, lentinian and certain other mushrooms, Thymus extracts, licorice root, dong quai, beta 1,3-glucan, noni, neem, gingko biloba, exercise, water (to aid detoxification), a positive attitude, the ability to forgive and be compassionate, and having long-term goals.