[rocknroll714]

Originally Posted by miko

Don't know, but anticholinergics block acetylcholine receptors, and Choline, ACL increase acetylcholine levels. Maybe Nootropics may help if they working on other rules, like piracetam? Oxybutynin is bad becauce it's blocking three M receptors, but it's cheap and available ( Ditropan ). Tricylic blocking mainly M1 receptors in brain, that's they can do excessive sweating, and all M3 blocking Oxybutynin is used in excessive sweating treatment. In Parkinsons, there is no dopamine, and too much acetylcholine, and that's why we have excessive sweating, seborrhea, drooling. M3 acetylcholine receptors respond for glands secretion. There is study on net that's say too much acetylcholine is one of the reasons of depression. Anticholinergics working on me, increase my mood, I think it's because, they somehow increase dopamine.

Indeed they do. Pro-muscarinics inhibit DA release in certain areas and are pro-depressive.

Nice pharmacology tidbits btw.